I find it telling that I made a observation about people not believing in science when it doesn't fit their preferences and multiple posts seemed to think that was somehow politically pointed.
Are you saying we're headed towards 50% likely infected or you think/have read that we're there already?k2aggie07 said:
Percent infected? Likely north of 50%, no new evidence is pushing the transmission rate down (if anything it is going up - if we take the Stanford study at face value eventual infection will be quite high).
Depending on people infected, that is a huge difference in deaths. And it is beginning to look like it will be < .5%. The difference in .3-.2% and 1% is the difference in shutting down the economy and not doing so. That model is utterly useless.k2aggie07 said:
Explain policies end up being wrong? I mean, how are you going to quantify that? With models.
The "growing sense" of pessimism is based off of... what, exactly?
The numbers are not difficult. Percent infected, times percent fatality, times population. Anyone can do this math. Population is probably widely agreed.
Percent infected? Likely north of 50%, no new evidence is pushing the transmission rate down (if anything it is going up - if we take the Stanford study at face value eventual infection will be quite high).
And percent fatality. Well, this is the whole ballgame here. And nothing new has been learned since early March when we settled on a 0.5-1% range. The only thing to narrow this (or disprove it) is serology testing, and we have barely begun getting results on that.
Seeing as no new information has come in, the growing sense is basically only due to lack of what most people would consider affirming experience. As in - "I don't see people dying in my city." But that's silly, they didn't see people dying in their city a month ago. It's not new information, it's driven by a lack of understanding of what to expect. The biggest problem we have is a lack of straight talk from leadership about what to expect.
PS Epidemic modeling is not a new field. That's why I think it's pretty likely the unmitigated models that most people handwave away probably have the highest predictive value. From there, things get shaky because you're modeling human behavior.
its way too early to say any policies on COVID have been wrong. that is NOT what i said.k2aggie07 said:
Explain policies end up being wrong? I mean, how are you going to quantify that? With models.
The "growing sense" of pessimism is based off of... what, exactly?
The numbers are not difficult. Percent infected, times percent fatality, times population. Anyone can do this math. Population is probably widely agreed.
Percent infected? Likely north of 50%, no new evidence is pushing the transmission rate down (if anything it is going up - if we take the Stanford study at face value eventual infection will be quite high).
And percent fatality. Well, this is the whole ballgame here. And nothing new has been learned since early March when we settled on a 0.5-1% range. The only thing to narrow this (or disprove it) is serology testing, and we have barely begun getting results on that.
Seeing as no new information has come in, the growing sense is basically only due to lack of what most people would consider affirming experience. As in - "I don't see people dying in my city." But that's silly, they didn't see people dying in their city a month ago. It's not new information, it's driven by a lack of understanding of what to expect. The biggest problem we have is a lack of straight talk from leadership about what to expect.
PS Epidemic modeling is not a new field. That's why I think it's pretty likely the unmitigated models that most people handwave away probably have the highest predictive value. From there, things get shaky because you're modeling human behavior.
Thanks, that's what I thought you were saying, I just wanted to be sure.k2aggie07 said:
We'll get there eventually, over ?? months (6? 12? 18??)
we've had a steady drip of antibody testing results over the past several days that, while not remotely sufficient to draw conclusions yet, are certainly 'new information' that has come in. these tests are consistently indicating vastly larger infection rates, which significantly reduces the death rate, which significantly impacts the modeling assumptions and projections. i don't know of a single antibody result to date that indicates an infection rate in the same order of magnitude as the early model assumptions.k2aggie07 said:
Seeing as no new information has come in, the growing sense is basically only due to lack of what most people would consider affirming experience.
k2aggie07 said:
This is my point. Beginning to look like <0.5% based on what?
That model is useless - what model?
i'm referencing that original model (2M US, 500K UK) that caused so much policy shift. the later models incorporated human behavior changes and the most recent revs appear pretty accurate. its not clear that, had this current projection been originally used, policy would not have been nearly so restrictive.k2aggie07 said:
Unfortunately there's been only one actual paper released about antibody testing as far as I can find, but I very well could be missing some. If you have links to any, I very much would like to read them. The one paper has some potentially serious issues.
We have a handful of press releases about results, but no papers, and none are using an FDA approved test kit. The USC and Stanford trials are being done by an overlapping team (USC doc worked on the Stanford paper) using the same Chinese manufactured kit. That kit has sensitivity and specificity measurements all over the map, (63.7-92.7% and 87%-99.5% respectively). So who knows what to make of both of those studies.
Media reports are not evidence, and they're also not models. That's the whole problem. We live in an era of fake news, rapidly disseminated information (often false), and widespread pandemic of the Dunning-Kruger effect.
The IC model is pretty interesting, as it said for total deaths with an R0 of 2.6, the range of predicted fatalities was 12,000 to 48,000 over a two year period. UK is at 17,337 right now. On what basis can we say this model was pessimistic?
k2aggie07 said:
I don't trust my gut on this. And frankly, I don't trust yours either.
Yet the mortality numbers are right in line with what was expected, <70yo COVID is not an issue, Nothing to fear.fig96 said:
We're getting into the part of the argument that a lot of us predicted weeks ago.
If the mortality numbers are lower than projected, people will complain about sheltering in place rather than realizing that sheltering in place is a large part of why the mortality numbers are lower than expected.
So am I. That's the point, there is a persistent misunderstanding about this. The model never changed. There was no later model. The original 2M / 500k was a baseline, and in the original paper was taken as unlikely because it didn't assume for spontaneous response. The original model is intact, is what is being used, and wasn't revised. Here, read it - note the date.Quote:
i'm referencing that original model (2M US, 500K UK) that caused so much policy shift. the later models incorporated human behavior changes and the most recent revs appear pretty accurate. its not clear that, had this current projection been originally used, policy would not have been nearly so restrictive.
Trump made this argument very clearly yesterday (his last question) when he projected hundreds of thousands or millions of deaths would have resulted had we not locked down.fig96 said:
We're getting into the part of the argument that a lot of us predicted weeks ago.
If the mortality numbers are lower than projected, people will complain about sheltering in place rather than realizing that sheltering in place is a large part of why the mortality numbers are lower than expected.
Ok. Let say 10,000 deaths. Than gives me a 1 in 3,000 chance. I'm still risking it. 30,000 deaths? So 1 in 1,000. Guess what? I'm still risking it.HouAggie2007 said:
You do realize it's 1,000 with a large amount of social distancing?
i understand your point and that the baseline IC model assumptions were modified to incorporate social distancing following the policy changes (the model assumptions were changed, if that is better terminology - sorry to be pedantic but a model with different assumptions incorporated mathematically into its parameters is a different model).k2aggie07 said:So am I. That's the point, there is a persistent misunderstanding about this. The model never changed. There was no later model. The original 2M / 500k was a baseline, and in the original paper was taken as unlikely because it didn't assume for spontaneous response. The original model is intact, is what is being used, and wasn't revised. Here, read it - note the date.Quote:
i'm referencing that original model (2M US, 500K UK) that caused so much policy shift. the later models incorporated human behavior changes and the most recent revs appear pretty accurate. its not clear that, had this current projection been originally used, policy would not have been nearly so restrictive.
The hooplah pushback and accusation that it was "revised down" started with Alex Berenson's twitter account and blew up. The lead author (Ferguson) actually had to take to twitter to clear the score. Didn't work, lie was shouted, retraction whispered.
There's only been one paper for antibody testing, and thats the Stanford one. USC and Chelsea haven't been published - no error bars, no test info. The TR was PCR, and is incredibly useful - but this isn't new. 56% asymptomatic is a far cry from what Stanford is saying which is 98%+ (50x reported)!
I wish it were that black and white. The problem with that line of thinking is that people who just don't care one bit and are going to behave as if nothing was going on could quite conceivably cause problems for people who are trying to be cautious by becoming spreaders.The_Fox said:Ok. Let say 10,000 deaths. Than gives me a 1 in 3,000 chance. I'm still risking it. 30,000 deaths? So 1 in 1,000. Guess what? I'm still risking it.HouAggie2007 said:
You do realize it's 1,000 with a large amount of social distancing?
Texans should be given the the chance to make their own cost/benefit calculation and then the individual choice to risk it or not. Period.
No, this is incorrect. The original paper took a baseline and studied the effect of intervention against the baseline. The model assumptions were not changed. There was no modification. There was no first or second publication. Just the one.Quote:
i understand your point and that the baseline IC model assumptions were modified to incorporate social distancing following the policy changes (the model assumptions were changed, if that is better terminology - sorry to be pedantic but a model with different assumptions incorporated mathematically into its parameters is a different model).
Yes. Next question.Player To Be Named Later said:I wish it were that black and white. The problem with that line of thinking is that people who just don't care one bit and are going to behave as if nothing was going on could quite conceivably cause problems for people who are trying to be cautious by becoming spreaders.The_Fox said:Ok. Let say 10,000 deaths. Than gives me a 1 in 3,000 chance. I'm still risking it. 30,000 deaths? So 1 in 1,000. Guess what? I'm still risking it.HouAggie2007 said:
You do realize it's 1,000 with a large amount of social distancing?
Texans should be given the the chance to make their own cost/benefit calculation and then the individual choice to risk it or not. Period.
Unless you think it's 100% black and white and anyone who wants to be cautious just shouldn't come out of their homes at all.
If I were 100% confident that the only people who would be affected by carrying on as normal were the ones carrying on as normal, then I'd be completely ok with wishing you the best of luck.
People use this, along with "Americans are selfish and won't change naturally in response to a deadly pathogen" as strawmen.fig96 said:
I quit listening to the pressers a few weeks back so I'll take your word for it
But you're right, Sweden is definitely the outlier and an interesting case study in all this I think in order to really compare we'll need to evaluate how different what they were doing actually was vs how society lent itself to that (high speed internet, lots of tech that easily works remotely, large single population, voluntary social distancing) and that's going to be tougher to quantify.
How is it a strawman?NASAg03 said:People use this, along with "Americans are selfish and won't change naturally in response to a deadly pathogen" as strawmen.fig96 said:
I quit listening to the pressers a few weeks back so I'll take your word for it
But you're right, Sweden is definitely the outlier and an interesting case study in all this I think in order to really compare we'll need to evaluate how different what they were doing actually was vs how society lent itself to that (high speed internet, lots of tech that easily works remotely, large single population, voluntary social distancing) and that's going to be tougher to quantify.
Thankfully American cities are unique and isolated enough to confidently make this comparison. Silicon valley very much fits that description, and they had the hardest and earliest lockdown in the US. As such, we can gain much when this is all over between the Swedish model and SV, for example.