I imagine Interstellar to be typical Nolan, but in space. Almost like Inception in space, as somebody else said. Actually, maybe more like a combination of Lord of the Rings and the Dark Knight, but in space...not the same sort of world obviously, but similar in its broad scope, phenomenal detail, and dark, violent uncertainty that runs throughout the plot.
This movie will be long. It will begin slowly to set up the world in which it is set, with characters that are compelling (and well cast). More and more will be revealed throughout the film, and the viewer will slowly be made aware of an extremely dark interstellar conspiracy or evil presence that must be dealt with by the protagonists, who come to realize their backs are up against the wall at the same pace the audience does.
I'm predicting it will be a two-part epic or a trilogy. Nolan can't explore an idea this massive in one movie.