Tips from the speed run guys
Raid perks. The new raid perks on the armor help tremendously throughout the entire run. The helmet allows for an instant grenade after a super use. The gloves give a 20% damage bonus on melee kill, which is huge. The class item provides a 25% damage bonus for a specified element ability type, which is also huge. These are the three main perks that speed up every section of the raid... by a lot.
Calus utilizes the skull spawn ratio mechanic. This means that depending on the ratio of people in the realm compared to the people in the throne room, more or less skulls will spawn in the realm. Most previous speedruns utilized a 2:4 throne/realm ratio. We ran an even 3:3 to start. However, once the skulls were about to start spawning, every player killed themselves except for one player in the realm (me) and one player in the throne room (Indica). This allowed for an even 1:1 ratio of skulls.