TX Cares Antibody study (natural vs vaccination)

96,262 Views | 629 Replies | Last: 2 yr ago by VaultingChemist
Charpie
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I just took my daughter in to get tested. She moved to CS for summer school. She has been sicker than a dog the whole time she was there...tested for covid twice and both times were negative. Doc has her on old school antihistamines and is sending her off to get allergy tested. She's never had these many allergy problems in her life. I'm tossing it up to moving to a new area. I remember being sicker than a dog when I moved to Austin so I hope it really is just that.
KidDoc
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We have had a tremendous increase in common respiratory viruses (RSV, parainfluenza, coxsackie, HMV) and, assuming she is college aged, they do things that often lend to massive transmission of these pathogens. That is more likely than grass allergy but the only way to really know is the allergy testing.

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BadMuthaClucka
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Took my first test yesterday, and just got results. Background on me:

29 years old
Not vaccinated.
PCR positive for covid in December 2020.
Somewhat mild case. Felt bad for a few days but recovered shortly after. Lost smell but not taste.

I am a high school teacher and am trying to decide if I should get the vaccine. To the health care workers or experts here, are these numbers good for adequate protection?


KidDoc
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That still shows robust immunity likely don't need vaccine yet. Hard to tell or predict when it will drop off without trending data over time.
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BadMuthaClucka
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Thanks! I will post the results of my next test here.
Kyle Field Shade Chaser
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KidDoc said:

That still shows robust immunity likely don't need vaccine yet. Hard to tell or predict when it will drop off without trending data over time.


Would T Cell and B cell response still provide longer term immunity even when the above numbers drop?
CDub06
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Wife got her results. On immune suppressive therapy. Had her second shot Feb 3.
dubi
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Not a Dr, but looks like she needs a booster ASAP.

Get Moderna.
KidDoc
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This looks like good vaccine response with no wild antibodies, same as myself last check.
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KidDoc
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Motracicletraficificker said:

KidDoc said:

That still shows robust immunity likely don't need vaccine yet. Hard to tell or predict when it will drop off without trending data over time.


Would T Cell and B cell response still provide longer term immunity even when the above numbers drop?

Probably but it is not well defined. Under research over the last 12 months.
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austinAG90
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Results back today. Also positive antibodies in April.

COVID-19 Antibodies, Spike Protein
Most Recent Results:
POSITIVE *
  • Out of range
Reference Range: [NEGATIVE]Jul2021Aug2021

COVID-19 Antibodies, Spike Protein (Quantitative)
Most Recent Results:
357
  • Out of range
Reference Range: [<0.8 U/ML]Jul2021Aug20210250500
August 20, 2021
Test Value : 357
Reference Range: <0.8
Units: U/ML
SARS-CoV-2 (COVID-19) Total Antibodies
Most Recent Results:
POSITIVE *
  • Out of range
Reference Range: [NEGATIVE]Jul2021Aug2021

SARS-CoV-2 (COVID-19) Total Antibodies Quantitative
Most Recent Results:
5.1
Jack Pearson
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I just had it on aug 9th....got my antibodies done on 8/20 and results back yesterday.
I am not vaxxed .


Is that really low Spike protein results?
Tabasco
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Jack Pearson said:

I just had it on aug 9th....got my antibodies done on 8/20 and results back yesterday.
I am not vaxxed .


Is that really low Spike protein results?



That's low but it takes a few weeks to build. Your 2nd draw will be a lot higher.
planoaggie123
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Just signed up. Going to try and go by today or some day this week after work....
Tabasco
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planoaggie123 said:

Just signed up. Going to try and go by today or some day this week after work....
register online (link on page one I think) so you can get the detailed numbers. Otherwise you will only get a positive/negative text.
planoaggie123
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Tabasco said:

planoaggie123 said:

Just signed up. Going to try and go by today or some day this week after work....
register online (link on page one I think) so you can get the detailed numbers. Otherwise you will only get a positive/negative text.

That is what I did. Signed up online. Seemed like a million questions. I had to do it on phone b/c work blocked the site but pretty sure i did it right lol. Got a text too.
MrJonMan
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Edit to ask: why is there such a drastic difference between the Moderna and Pfizer antibody numbers? Obviously I've only had one shot but would've expected it to be higher than that

First Pfizer shot 8/5, so 18 days post shot as I had blood taken yesterday afternoon

Spike
109

Negative for natural

Curious to see how much that spike number changes once I receive the second shot
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GeographyAg
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Hey, KidDoc,

Mr. Geo and I just got our antibody test results this morning. We're both surprised that our natural antibodies are negative because we've been around several people who have tested positive soon after we were with them. It seems our vaccines worked.

He had the Moderna vaccine four months ago and his Spike number is 2194.

I, on the other hand, had the Pfizer five months ago. My Spike number is only 216.

My question for you is, should I try to get a booster or dose of the Moderna if I can?

Also, my parents live with us. They also got the Pfizer a few weeks before I did. Should I try to get them boosters of the Moderna?

They haven't had the antibody tests, but I'm assuming their numbers are like mine. They have not had covid, and they've been living life normally, going out and about as usual (no mask, of course). They're 84 and 81.

I'd appreciate any advice you might be able to give.
If I’m posting, it’s actually Mrs GeographyAg.
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planoaggie123
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Missed going yesterday after work. Had a late request come through and didn't get out till 6.

Going at lunch today.

I maybe shouldn't be, but I am sort of surprised how many people are negative for natural 1.5 years in. I hope i am wrong, but to be honest, I expect to be negative for natural. Only can think of two times I have felt sick-ish and no high temps or loss of taste/smell. While I am not licking doorknobs and living wild, I have been back in office for 13 months, family goes out to eat weekly, go to church every Sunday and teach 5 year olds, and go to social gathering frequently, all without a mask. I know others who have hunkered down and still get delivery for food and groceries and wear mask and WFH that have gotten COVID. So confusing.
dubi
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planoaggie123 said:

I know others who have hunkered down and still get delivery for food and groceries and wear mask and WFH that have gotten it. So confusing.
I had a vet med professor who religiously wore a N95 mask whenever she was outside of the house and made her young kids mask. She came down with it and I never wore a mask and didn't.

It is really hit and miss on who gets it.
Charpie
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I asked my pediatrician friend about this. She said it really didn't matter. Your body would kick the antibodies into high gear if it was exposed to COVID.

I got Moderna as well and I was in the 900's.

As far as being exposed to COVID and not having the natural antibodies, the same can be said for my daughter. She was fully vaccinated in May. She's been around lots of teenagers all summer long from summer school and fish camp with COVID. She continues to test negative for the virus and antibodies.
GeographyAg
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Charpie said:

I asked my pediatrician friend about this. She said it really didn't matter. Your body would kick the antibodies into high gear if it was exposed to COVID.

I got Moderna as well and I was in the 900's.

As far as being exposed to COVID and not having the natural antibodies, the same can be said for my daughter. She was fully vaccinated in May. She's been around lots of teenagers all summer long from summer school and fish camp with COVID. She continues to test negative for the virus and antibodies.


That's good to know. Thanks.
If I’m posting, it’s actually Mrs GeographyAg.
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KidDoc
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GeographyAg said:

Hey, KidDoc,

Mr. Geo and I just got our antibody test results this morning. We're both surprised that our natural antibodies are negative because we've been around several people who have tested positive soon after we were with them. It seems our vaccines worked.

He had the Moderna vaccine four months ago and his Spike number is 2194.

I, on the other hand, had the Pfizer five months ago. My Spike number is only 216.

My question for you is, should I try to get a booster or dose of the Moderna if I can?

Also, my parents live with us. They also got the Pfizer a few weeks before I did. Should I try to get them boosters of the Moderna?

They haven't had the antibody tests, but I'm assuming their numbers are like mine. They have not had covid, and they've been living life normally, going out and about as usual (no mask, of course). They're 84 and 81.

I'd appreciate any advice you might be able to give.
They STILL have not released the data on which they based the booster decision. So I have no way to really advise you on this.

There is a lot of consternation about this recommendation, it is not without controversy. At this point I have no intention of getting a booster until there is more data (Moderna dose #2 1/29)
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GeographyAg
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KidDoc said:

GeographyAg said:

Hey, KidDoc,

Mr. Geo and I just got our antibody test results this morning. We're both surprised that our natural antibodies are negative because we've been around several people who have tested positive soon after we were with them. It seems our vaccines worked.

He had the Moderna vaccine four months ago and his Spike number is 2194.

I, on the other hand, had the Pfizer five months ago. My Spike number is only 216.

My question for you is, should I try to get a booster or dose of the Moderna if I can?

Also, my parents live with us. They also got the Pfizer a few weeks before I did. Should I try to get them boosters of the Moderna?

They haven't had the antibody tests, but I'm assuming their numbers are like mine. They have not had covid, and they've been living life normally, going out and about as usual (no mask, of course). They're 84 and 81.

I'd appreciate any advice you might be able to give.
They STILL have not released the data on which they based the booster decision. So I have no way to really advise you on this.

There is a lot of consternation about this recommendation, it is not without controversy. At this point I have no intention of getting a booster until there is more data (Moderna dose #2 1/29)
Gotcha. Thanks.
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planoaggie123
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Just gave my blood....went early as did not want to mess with a "lunch rush"....

Now I wait...
planoaggie123
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that was super fast....negative on all accounts....
Max06
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Got my results today- pretty interesting stuff. I would be interested to know what the 95% CI range of values is.

N: +
N: 60.4
S: +
S: 324
ATXaggie83
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Did my first draw yesterday 8/25
60 years old
2nd Moderna on 3/26

S >2500
N negative
Player To Be Named Later
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I had my 2nd dose of Moderna in January. Where are y'all having your antibody levels tested at?
BadMuthaClucka
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Follow this link.You fill out the survey and go to a local clinic they are partnering with. No appointments, just walk in. I got my results the next day.

https://sph.uth.edu/projects/texascares/
Player To Be Named Later
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Thanks. Got signed up. Now I need to swing in and get my blood drawn.
KidDoc
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Player To Be Named Later said:

I had my 2nd dose of Moderna in January. Where are y'all having your antibody levels tested at?
Post your results if you don't mind. I'm in Aggieland so cannot really enroll in the study and my 2nd dose of Moderna was 1/29/21.

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MiMi
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S
Anyone in Texas can enroll in the study. I live in College Station and participated. There is a CPL lab in the medical building next to St. Joe hospital on Rock Prairie.
dubi
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MiMi said:

Anyone in Texas can enroll in the study. I live in College Station and participated. There is a CPL lab in the medical building next to St. Joe hospital on Rock Prairie.
We have several CPL's in BCS.
KidDoc
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Good to know! When I glanced at the website it only listed the major metro centers to enroll.
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