TX Cares Antibody study (natural vs vaccination)

96,170 Views | 629 Replies | Last: 2 yr ago by VaultingChemist
Tabasco
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MiMi said:

Quote:

This study should give some interesting info once its done.
Here is the link to the study dashboard where they update and post their preliminary results. I've been watching it for the past 3 months and it looks like they are only reporting natural antibody positive tests or they are not breaking down the positives into natural and spike protein (vaccine) positive groups. TXCARES Dashboard
Haven't looked yet, but thank you so much for the link! Blue star.
Tabasco
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MiMi said:

Quote:

This study should give some interesting info once its done.
Here is the link to the study dashboard where they update and post their preliminary results. I've been watching it for the past 3 months and it looks like they are only reporting natural antibody positive tests or they are not breaking down the positives into natural and spike protein (vaccine) positive groups. TXCARES Dashboard
Damn, 12K participants, and nothing but white people (90%)
Forum Troll
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AG
I guess I shouldn't be surprised that 70% of the respondents are female.

Also I think Hispanics are lumped in under whites in the race category.
dubi
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CPL emailed me:

Quote:

Hi DUBI,

Your lab results have been released and are ready to be viewed at www.cpllabs.com/sonicmyaccess. Please log on to your account to access your results and learn more about your health.



Quote:

Then when you login it will prob take you to a page that says your results will be uploaded in 48 hrs. But they prob won't, so call 512-339-1275 give them your name DOB and they will uplaod your full results within an hr.
It seems that i wouldn't have to call since them emailed me... Maybe incorrect assumption?
thirdcoast
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Thanks for dashboard link!

Unfortunately, this is disappointing that they didn't utilize the "N" protein as confirmation of prior infection. Why rely on PCR and self reporting when you have that data point for every subject?

What I would like to see is how any self reported "Yes" or "No" to prior infection and how many of each group actually had the natural antibody?

They need a pie chart with 4 groups of seroprevalance:
Vaccinnated only antibody (S)
Vaccinated and prior infection (S & N)
Unvaccinated prior infection (S & N)
Unvaccinated no prior infection (nothing)


Maybe the dashboard will get revised with more useful charts going fwd.

BlackGoldAg2011
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thirdcoast said:

Thanks for dashboard link!

Unfortunately, this is disappointing that they didn't utilize the "N" protein as confirmation of prior infection. Why rely on PCR and self reporting when you have that data point for every subject?

What I would like to see is how any self reported "Yes" or "No" to prior infection and how many of each group actually had the natural antibody?

They need a pie chart with 4 groups of seroprevalance:
Vaccinnated only antibody (S)
Vaccinated and prior infection (S & N)
Unvaccinated prior infection (S & N)
Unvaccinated no prior infection (nothing)


Maybe the dashboard will get revised with more useful charts going fwd.


reading through the dashboard guide, it appears that they did use the N protein. it looks like for the first graph you posted, that is only looking at what percentage of the study group shows antibodies from the virus (not vaccine only) but maybe im reading that wrong. the red and blue pie chart is just what you are asking for, that is self reported yes/no for prior infection. the bar chart right below that shows what percentage of each of those self reporting groups have detectable antibodies from the virus


edit:finally figured out why the image wasnt showing, apparently the autogenerated character string from imgur looked too much like a swear word for TexAgs
dubi
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Moderna x2 Jan and February

MiMi
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S
Why the thumbs down? That's a great spike protein level 6-months post vaccine.
dubi
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MiMi said:

Why the thumbs down? That's a great spike protein level 6-months post vaccine.
I had gripes about having to call CPL just edited my post to show the results.

So that is good?
MiMi
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S
Quote:

So that is good?
Yes, I believe the upper limit of the test is 2500 for the spike protein antibody. You have very good antibody level from the vaccine, especially given the fact that it's been 6 months since your 2nd dose. However, you have no natural antibodies, which means you likely have never had Covid
thirdcoast
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"Self reported" prior infection may be different than actual results confirming N protein. Hopefully not much different though...

I would still like to see the 4 groups as that provides most insight.
Dolphin Roper
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Did my first round of Texas Cares testing yesterday.

History: Covid-19 in March 2020 (16+ months ago), no vaccine
S Protein: >2500
N Protein: 100

Question - does anyone know why all tests, even positive/negative, say 'out of range'?
MiMi
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S
Quote:

Question - does anyone know why all tests, even positive/negative, say 'out of range'?
Because their reference range for the qualitative test is 'Negative' and their reference range for the quantitative test is <0.8 for spike protein and <1 for natural antibodies. If your results are outside their established reference range it will be listed as 'out of range.'
Dolphin Roper
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I expected to be positive for both, but surprised by how high the #s are!
thirdcoast
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How bad was your illness?...I would assume pretty bad if there is any correlation to severity and your off the charts immune response.

On a side note. I'm wondering if my next blood test will show an increase in my antibody levels. I think I could have caught delta a few weeks ago before it blew up in news. My symptoms were very mild, slight sore throat and runny nose. I took some Sudafed and benadryl and went on with my weekend. I thought it was allergies, but if my levels go up, I would take that as natural reinfection.
Dolphin Roper
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I would say moderately severe - I did develop pneumonia in both lungs and was hospitalized for a few days. Oxygen level got to low 90s. Ran fever for about two weeks, lot of symptoms (stomach issues, body aches, cough, severe dry mouth, trouble breathing, fatigue, etc). Treatment was minimal at the time since it was so early on - was sick at home for a week with only Tylenol and albuterol, after hospital admission I was put on a lot of antibiotics and HCQ. Sent home after a few days to continue to recover at home.

With my #s being so high, I am wondering if I had a really strong immune response, or if I have been exposed/infected again and didn't know it?

Have been debating if I should get the vaccine, but I'm thinking no at this point?
Charpie
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My results came in.

Vaccinated in February with Moderna

S Protein: 976

N Protein: 0
HeardAboutPerio
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Was this study posted? A friend just sent me this link on antibody stability post infection in Spain:

https://www.usnews.com/news/health-news/articles/2021-08-09/covid-antibodies-stable-7-months-after-infection-study
Tabasco
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Tabasco said:

She finally just called and results posted 10 min later.

Tabasco Wife (Infected Jan '20/Vaccinated Mar' 20 Pfizer)

Feb 2 antibody (post covid, pre-vaccine):
S: (was not yet being measured)
N: 6

Mar 4 antibody (post covid, post vaccine 1 and 2)
S: >2500 (they stop measuring at 2500)
N: 36
Wife just got her 3rd and final results (the second quoted above should be May 4 btw):

August 9 antibody (post covid in Jan 2021, post Pfizer March 21)
S: 1664
N: 14.9
thirdcoast
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I'm not a doctor, but heard a few anecdotal stories of pretty bad responses to vaccines if taken shortly after infection. I would assume a high immune defense system would put up a pretty good fight vs someone like me with much lower levels.

It seems people with no natural infection also had a harder time with 2nd shot. Probably a similar effect to a naturally immune person getting boosted.

My plan is to get a booster if my levels on 2nd sample dont go up. So I'll post my reaction then.
Hopefully they don't scrap the study early.
petebaker
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Immune System IgG IgA Immunoglobulin rapid rise to 'Novel Corona Virus' should not be possible but is measured in the blood of most people already.

IgM slow around 4 weeks would be expected in consensus logic but is not the case
https://www.bitchute.com/video/xGtotlUj1a1f/ Dr Sucharit Bhakdi 12 minutes good faith science

Sucharit Bhakdi
Born
November 1, 1946 (age 74)
Washington, D.C., U.S.
Nationality
Thai-German
Alma mater
Known for
Microbiology,[url=https://en.wikipedia.org/wiki/Sucharit_Bhakdi#cite_note-br24-1][1][/url] fringe ideas about COVID-19[url=https://en.wikipedia.org/wiki/Sucharit_Bhakdi#cite_note-spiegel-2][2][/url]
Awards
Order of Merit of Rhineland-Palatinate, Aronson Prize
Scientific career
Fields
Medicine/surgery, bacteriology and atherosclerosis
Dolphin Roper
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Decided to get my two kids tested as well.

Kid #1:
S Protein: negative
N Protein: 60.8

Kid #2:
S Protein: negative
N Protein: negative

Neither are old enough for vaccination, and neither have been diagnosed with Covid, though it looks as though Kid #1 must've had it at some point? Not sure why S protein is negative, though, with N protein being positiive - would've expected both to be positive.
Tabasco
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Dolphin Roper said:

Decided to get my two kids tested as well.

Kid #1:
S Protein: negative
N Protein: 60.8

Kid #2:
S Protein: negative
N Protein: negative

Neither are old enough for vaccination, and neither have been diagnosed with Covid, though it looks as though Kid #1 must've had it at some point? Not sure why S protein is negative, though, with N protein being positiive - would've expected both to be positive.
The S-protein number is vax antibodies (spike protein), so they should be zero.

My daughters numbers for N were 35 (feb), 20 (may), 5 (aug), but we don't know when she got it. She was probably asymptomatic.

Dolphin Roper
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Your daughter was negative for S protein on all of her tests?

Maybe with mild/asymptomatic infection that is normal? I am not vaccinated but my S protein # is >2500 over a year after infection.
Tabasco
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She was negative for s-protein until she got the vaccine, then she was >2500 for s.

I'm fairly certain N-protein is the actual natural Covid antibodies, and the S is for vaccine. If anyone has a positive S-protein value, it means they got the vaccine.

If I understand you correctly, that you got Covid (I know you did, I remember you posting your experience), but ha e not gotten the vaccine, your S-protein should be zero. If you maintain you have not gotten vaccine, but got a s-protein result, I would assume that was not your sample.

I'm not an expert with this, but that has been my understanding all along. I will bow out and let others weigh in.

Tabasco
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And if my sample swap theory is correct, I am going to predict your sample 2 is going to have a low N (under 10), and an S at 0, just to be on record. Again, not my field at all, but just a hunch (as rare and absurd as swapping samples would be). CLP seemed pretty unprofessional, at least her one I went to in sugar land. Never verified my name or identifying information before putting a sticker on vile (I don't recall them putting one on, and pretty sure they didn't even alcohol swap my arm).
Zobel
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S is for the spike, and N is for the nucleocapsid. If you had infection, would expect to have both. The vaccines only deal with spike, which is what the virus uses to attach to your cell, so if you have been vaccinated you should have S but not N.
Tabasco
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Zobel said:

S is for the spike, and N is for the nucleocapsid. If you had infection, would expect to have both. The vaccines only deal with spike, which is what the virus uses to attach to your cell, so if you have been vaccinated you should have S but not N.


Thanks for clarifying. I miss understood and stand corrected. Thanks for info.
Tabasco
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And to further eat crow, I went back and looked at page one, and saw OP have Covid and no vaccine, and had both S and N values above zero. Not sure what I was thinking.
jograki
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How long did it take for y'all to see your dashboard after getting your results in the text? My text came yesterday but I still see nothing on the report link. Thanks for info
Tabasco
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jograki said:

How long did it take for y'all to see your dashboard after getting your results in the text? My text came yesterday but I still see nothing on the report link. Thanks for info
immediate. Call them or email. Links are on page one I believe. they respond fast after you contact them.
Tabasco
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jograki said:

How long did it take for y'all to see your dashboard after getting your results in the text? My text came yesterday but I still see nothing on the report link. Thanks for info
and did you set up the online account (link posted page one)?
jograki
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Thanks! Called and left a message. Yes I had setup my login account before going to the lab, so maybe they just need to click one more thing for me.
TarponChaser
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So I tested positive for covid (mild case) on like November 30 of last year. Had repeated exposures since then and nothing. Just went to CVS an hour ago and did the antibody test and still positive for the IgG Covid antibodies.

At least in this guy we're looking at 9 months that they're showing up post-infection.
jograki
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From all the results everyone else is posting, it's hard to determine a trend. I just got access to my dashboard and I have S >2500 and N 4.6. Got Pfizer in March/April and had Covid with only "allergy" symptoms 3-4 weeks ago. Weird that my N is so low.
 
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