NICU Dad said:
No unless you want total kidney failure.
Kidney failure is COVID patients is almost entirely driven by the combination of persistent hypoxia and renal microthrombi. Remdesivir is a largely a confounder in that equation, as it's usually reserved for patients on at least 4-6 L NC (varies by facility). When accounting for severity of illness and correcting for other things, rates of kidney damage attributable to remdesivir are relatively low. MUCH lower than many of the antibiotics we give people all the time.
Now, the more data that emerges the less benefit it seems remdesivir has. Anecdotally (admittedly a worthless data point) I don't see it benefiting most of my patients who get it. But it's safety concerns are vastly overblown by those who wish to contrast it with things like HCQ and ivermectin.
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