Also the American Journal of Medicine supports the guidelines laid forth in the Covid Home Treatment Guidelines.
https://www.amjmed.com/article/S0002-9343(20)30673-2/fulltextCombination mix of anti-viral medicines with Monoclonal antibody therapy started as soon as symptoms occur. Medicines to decrease inflammation, such as corticosteroids (called immunomodulators). Anticoagulant therapy to prevent blood-clots that can cause strokes, heart attacks, kidney shut-down, and death. Non-prescription supportive treatments with zinc, vitamin D, vitamin C, electrolyte drinks. Home-based oxygen support, such as with an oxygen concentrator.
Antiviral Agents: These must be started quickly at STAGE 1 (Days 1-5): Symptoms include sore throat, nasal stuffiness, fatigue, headaches, body aches, loss of taste and/or smell, loss of appetite, nausea, diarrhea, fever. These medicines stop the virus from (1) entering the cells and (2) from multiplying once inside the cells, and they reduce bacterial invasion in the sinuses and lung:
*Hydroxychloroquine (HCQ) with azithromycin (AZM) or doxycycline OR Ivermectin with azithromycin (AZM) or Doxycycline. Either combination above must also include zinc sulfate or gluconate, plus supplemental vitamin D, vitamin C & B complex. Monoclonal antibody therapy (tocilizumab) should also be started in stage 1.
Anti-inflammatory Agents - Corticosteroids ("steroids"): Oral and Nebulized. These are started at STAGE 2 (Days 3-14) to reduce inflammation, the cause of added damage to the lungs and critical organs. Symptoms include worsening cough, difficulty breathing, chest heaviness/tightness or chest pain. As inflammation damages the airways interfering with normal oxygen-carbon dioxide exchange, blood oxygen levels drop and people experience loss of focus, drowsiness, confusion, difficulty concentrating, low energy and severe fatigue. The exaggerated Inflammation response in COVID further increases the risk of blood clots.
Prescription medicines and other support added now to Stage I medicines are:
nebulized budesonide to help penetrate the lungs and reduce inflammation, oral prednisone, methylprednisolone, dexamethasone, colchicine may also be added to reduce inflammation, full strength adult aspirin 325 mg to reduce inflammation and risk of blood clots, home oxygen concentrator may be needed to improve oxygen levels.
Stage 3 Prescription Anticoagulants ("blood thinners"): STAGE III (Day 7 and beyond): Symptoms seen in Stage II intensify. Difficulty breathing becomes extreme, oxygen levels drop sharply, risk of heart attack or stroke increases. At this point, people are critically ill. The medicines to be added to Stage 1 and 2 medicines now include:
Aspirin 325 mg unless told not to take by your doctors And/or low molecular weight heparin injections (e.g. enoxaparin [Lovenox]) OR apixaban (Eliquis), or rivaroxaban (Xarelto), or dabigatran (Pradaxa) or Edoxaban (Savaysa) in standard doses for 5 to 30 days If these added steps do not lead to improvement, or the patient becomes unstable, a 911 call is warranted for ER evaluation and hospital admission so that more aggressive IV medications (such as Remdesivir, Regeneron, and others) should be considered, and more intensive ventilation regimens are possible in ICU settings.
Stage 4 Vitamins, Supplements, and Oxygen. Zinc sulfate, gluconate or citrate. These forms are available in pharmacies, health food stores, and sold online. Zinc sulfate 220 mg provides 50 mg elemental zinc, the recommended anti-viral dose. Zinc in the form of zinc picolinate form is not recommended following reports of liver damage and tumors from studies about 20 years ago. Following these reports, the German Commission that regulates supplements used in medical practice in Germany banned this form of zinc. Vitamin D3, preferable in oil in capsules for better absorption. Recommended doses for anti-viral benefit vary from 5000 IU or more for 5-30 days Vitamin C with bioflavonoids for antioxidant, anti-inflammatory effects. Dose recommendations from our contributors vary from 1000 mg (1 gram) once or twice a day up to 4 or more times a day. Vitamin C IV drips are also a option as well.
