AG 2000' said:

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Mr.Infectious said:

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Sorry if you like him. I voted for him too. IMO he doesn't have the personality for this kind of issue. Fighting political fights yes. Handling fast moving situation that requires tact and delicate use of language, not so much.

Patton was a great fierce general on the front lines. Ike was a master strategist w political acumen. Both great men and great at the job in front of them. But switch the roles and you get completely different outcomes.


Trump is Patton. This situation requires Eisenhower type.

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Howabout we start a political coronavirus thread.

Really tired of you showing up to b*tch about Trump every page.

Let's keep this focused on news please.

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I mean obviously we would be better with Biden, he would speak in circles so much and probably call it an Ebola pandemic so we would all get confused and forget Covid-19 us even a thing. Maybe corn-pop can fight the virus with his chain but hopefully his sister wife doesnt get infected....But I mean I think he is actually running for Senate anyways so not sure he is the face we need leading the fight either

I'm not commenting either way, just sounded like Trump's usual rambling stream of verbiage clumsily trying to make a statement.

cisgenderedAggie said:

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I think that's usually what they are doing when they develop vaccines...trying to get a target for the body to react to. That said, developing vaccines is not something I have any experience with.

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I have some experience with it. The biggest problem is, after the development of the vaccines, doing the clinical trials takes a ton of time. Drug trials have to be done to determine how effective they are and how much negative / harmful effects do they cause. That takes time. I strongly believe that it will take us at least 18 months to develop an effective vaccine to this virus. In China, a vaccine could probably be made sooner since they could bypass ethics in testing procedures that our medical personnel would have to follow.

Does anyone else think it would be helpful to have a separate thread that strictly discusses steps we can take as individuals to mitigate our families' risk and prepare for possible healthy or sick self-quarantine?

There is a fair amount of that mixed in on this thread, but such a lengthy news-based thread really isn't useful as a clearinghouse for info about how to manage risks and symptoms.

Tanya 93 said:

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MidTnAg said:

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Probably no human on earth has had any exposure to any portion of this coronavirus that enabled their immune system to produce antibodies against it. Thus, we are at its mercy and hope it doesn't spread like the H1N1 virus did. It may have at least a 15% kill rate in those over 65 with any respiratory problems and a 1% to 3% for all other adults over 30. Hopefully, it will not spread rapidly.

We have very few test kits in the US so we do not have much accurate information on this problem here. No matter, please do not pay any attention to what our POTUS says. Especially, if you have significant flu-like symptoms, please do NOT go to work like the POTUS suggested.

Listen only to the medical experts. PLEASE!

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When did he say it is okay to go to work with flu like symptoms? I have a son with the stomach flu, so I haven't watched the news in the last day

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Quote:

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"Because a lot of people will have this and it's very mild. ... So if, you know, we have thousands or hundreds of thousands of people that get better, just by you know, sitting around and even going to work, some of them go to work, but they get better."

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He is talking about 80%+ of the cases being mild and the fact that some people will go to work and be fine. He didn't say they SHOULD go to work.

Trump is always going to try to put the best spin on a situation like this. And his opponents will always try to use his words against him.

Trumps handling has been extremely disappointing and I'm not sure he is fully understanding what can happen here. I've read even yesterday they aren't even screening people coming in from Italy... how is that possible. All flights from Asia should have been shut down immediately.

Thank you It didn't seem like he would say you should go to work sick.

Shanked Punt said:

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I'm not commenting either way, just sounded like Trump's usual rambling stream of verbiage clumsily trying to make a statement.

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Nowhere in there did Trump say it is ok to go to work. He said even some of them go to work

sawthemoffxx said:

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Trumps handling has been extremely disappointing and I'm not sure he is fully understanding what can happen here. I've read even yesterday they aren't even screening people coming in from Italy... how is that possible. All flights from Asia should have been shut down immediately.

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Eh. People always gripe about the President in a crisis, especially if he's got an R after his name.

MidTnAg said:

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cisgenderedAggie said:

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I think that's usually what they are doing when they develop vaccines...trying to get a target for the body to react to. That said, developing vaccines is not something I have any experience with.

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I have some experience with it. The biggest problem is, after the development of the vaccines, doing the clinical trials takes a ton of time. Drug trials have to be done to determine how effective they are and how much negative / harmful effects do they cause. That takes time. I strongly believe that it will take us at least 18 months to develop an effective vaccine to this virus. In China, a vaccine could probably be made sooner since they could bypass ethics in testing procedures that our medical personnel would have to follow.

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http://ir.inovio.com/news-and-media/news/press-release-details/2020/Inovio-Accelerates-Timeline-for-COVID-19-DNA-Vaccine-INO-4800/default.aspx

Interested in your thoughts on this.

techno-ag said:

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sawthemoffxx said:

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Trumps handling has been extremely disappointing and I'm not sure he is fully understanding what can happen here. I've read even yesterday they aren't even screening people coming in from Italy... how is that possible. All flights from Asia should have been shut down immediately.

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Eh. People always gripe about the President in a crisis, especially if he's got an R after his name.

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Eh, when the death toll starts mounting these won't be gripes.

Clean your damn phone!

sawthemoffxx said:

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techno-ag said:

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sawthemoffxx said:

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Trumps handling has been extremely disappointing and I'm not sure he is fully understanding what can happen here. I've read even yesterday they aren't even screening people coming in from Italy... how is that possible. All flights from Asia should have been shut down immediately.

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Eh. People always gripe about the President in a crisis, especially if he's got an R after his name.

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Eh, when the death toll starts mounting these won't be gripes.

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Yeah but it's a political thing more than anything. The President is not out there killing people, despite what the media would have you believe.

MidTnAg said:

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cisgenderedAggie said:

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I think that's usually what they are doing when they develop vaccines...trying to get a target for the body to react to. That said, developing vaccines is not something I have any experience with.

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I have some experience with it. The biggest problem is, after the development of the vaccines, doing the clinical trials takes a ton of time. Drug trials have to be done to determine how effective they are and how much negative / harmful effects do they cause. That takes time. I strongly believe that it will take us at least 18 months to develop an effective vaccine to this virus. In China, a vaccine could probably be made sooner since they could bypass ethics in testing procedures that our medical personnel would have to follow.

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Trials can move quick when the conditions are right. There's loads of old people in nursing homes probably in the early stages of panic, so recruitment wouldn't need to be a bottleneck. I'm curious how much efficacy can really be warranted. I don't see how it's ethical to run a controlled trial on an infectious disease, especially one with this kind of propensity for severe complications.

Is there a reason that a small stage safety trial can't be implemented, just to show that it isn't causing cytokines storms or something very dangerous, then immediately go into post-marketing like trials? Regulatory decisions are always risk/benefit. For some populations, the risk/benefit makes sense here. I'd worry that manufacturing and distribution are the most problems bottlenecks.

If they are in ICU, they probably were infected 10 days ago.

akaggie05 said:

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MidTnAg said:

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cisgenderedAggie said:

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I think that's usually what they are doing when they develop vaccines...trying to get a target for the body to react to. That said, developing vaccines is not something I have any experience with.

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I have some experience with it. The biggest problem is, after the development of the vaccines, doing the clinical trials takes a ton of time. Drug trials have to be done to determine how effective they are and how much negative / harmful effects do they cause. That takes time. I strongly believe that it will take us at least 18 months to develop an effective vaccine to this virus. In China, a vaccine could probably be made sooner since they could bypass ethics in testing procedures that our medical personnel would have to follow.

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http://ir.inovio.com/news-and-media/news/press-release-details/2020/Inovio-Accelerates-Timeline-for-COVID-19-DNA-Vaccine-INO-4800/default.aspx

Interested in your thoughts on this.

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Exactly. The risk is it is more dangerous than the disease or is shown to be clearly useless. Then you have to scale production. I don't see FDA standing in the way absent an alternative.

VaultingChemist said:

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If they are in ICU, they probably were infected 10 days ago.

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And probably exposed dozens or hundreds of people by now.

aginlakeway said:

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Shanked Punt said:

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I'm not commenting either way, just sounded like Trump's usual rambling stream of verbiage clumsily trying to make a statement.

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Did you listen to that? Do you think the twitter statement is accurate? Or do you not care how misleading (wrong) it is?

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I said it was a rambling statement, which it was. I didn't say I agreed with the tweet. That was the first video clip I found of the statement, and felt it was very relevant to hear what Trump said rather than go off of other's statements on the matter.

So early on in the US, I think there was an infected person on the verge of death that was given some sort of antiviral as a last ditch effort... which ended up saving the person's life.

In the case of new vaccines, can the same approach be used or is it too late in the process for a vaccine to work at that point?

Italy getting hit hard

Mr.Infectious said:

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When you say "things are trickling in" what do you mean? What type of products? Finished consumer goods, dog food, clothing, furniture, pharmaceuticals, components for machinery, etc????

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Specialty apparel.

UncoverAg00 said:

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So early on in the US, I think there was an infected person on the verge of death that was given some sort of antiviral as a last ditch effort... which ended up saving the person's life.

In the case of new vaccines, can the same approach be used or is it too late in the process for a vaccine to work at that point?

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Yeah. Does Tamiflu help?

Trump last week (at presser):

"We only have 15 cases and soon we'll have less."

Trump this week:

Looking forward to the update next week. :/

New York is going to get dicey pretty quick it seems. And a 40 yr old in ICU isn't a good sign either....

hoosierAG said:

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New York is going to get dicey pretty quick it seems. And a 40 yr old in ICU isn't a good sign either....

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With their dependence on public transportation, I could see it spreading fairly quickly. That is one thing about Houston. Almost everyone drives

My daughter got a prescription for Tamiflu a few weeks ago, before I was really following this. Pharmacist filled an extra bottle with the prescription. Thought it was odd, but maybe they knew something. I'm not sure there's any reason to think it would work, but am thankful to have it just in case.

No. Tamiflu is a monoculture of antibodies for influenza viruses. Basically just floods your body with synthetic antibodies. Won't work on anything other than influenza.

Edit: I am an idiot and this post is incorrect.

k2aggie07 said:

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No. Tamiflu is a monoculture of antibodies for influenza viruses. Basically just floods your body with synthetic antibodies. Won't work on anything other than influenza.

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Tamiflu is not antibodies. It's an inhibitor that blocks an enzyme used in viral production.

https://en.m.wikipedia.org/wiki/Oseltamivir

I don't know if coronaviruses use this mechanism

College roommate is an MD. First he told me that some avian flu caused death in Canada when people had a flu shot that year (dirty lie but it maybe had a negative effect) and now this about tamiflu. Can't trust docs, man.

Quote:

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Specialty apparel.

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Obligatory : How you doin'?



It will be interesting to see which products have delays, shut downs vs those that make it in easier. Irish is reporting his poultry is making it in. Your apparel is on the board.

I've got a friend w cable assembly/wire harnesses for medical devices that are delayed due to component shortages. Same w a friend in paper and plastic restaurant supplies.