Trump gathers the FDA, CDC, experts, and the heads of all the large pharma companies into a room and asks what can we as the government do to expedite the process of therapeutic medicine and vaccine development and this is your response? Pathetic. There is an hour long video of this that is public.Shanked Punt said:
It appears a "solid flu vaccine" will not work on the coronavirus.
China Coronavirus Outbreak Spreads; Hundreds Infected As Human-To-Human Transmission
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Anybody have any other mr infectious doozies? Here are a couple that stand out to me.
-warm weather theory debunked because a case showed up in the Dominican Republic
-CV may bankrupt the health insurance industry
-warm weather theory debunked because a case showed up in the Dominican Republic
-CV may bankrupt the health insurance industry
bkag9824 said:tysker said:
23 more? Its as if the Iranian parliament is going around licking each others faces
Praying multiple times a day in very close proximity to a lot of other people miiiiight have something to do with it.
There is more to this story
Do you still believe this?Quote:
Once we have dozens of cases around the country then yes, we should let it go.
Is it time to let it go?
What's the point of terrible takes? Takes away from what should be an informative thread.
I'll stand by those takes.
Come November Trump is going to regret the stock market and initial CV tweets from a couple days ago.
As far as insurance companies go, they won't be able to pay everything out when this goes full pandemic.
Come November Trump is going to regret the stock market and initial CV tweets from a couple days ago.
As far as insurance companies go, they won't be able to pay everything out when this goes full pandemic.
https://marlin-prod.literatumonline.com/pb-assets/journals/research/cell/CELL_S0092-8674%2820%2930229-4.pdf
ACE2 is the entry point and it appears the entry can be blocked by a known protease inhibitor.
Interestingly, other early days studies available online posit that ACE2 is expressed in Asian males in higher concentrations than other race / gender combinations.
ACE2 is the entry point and it appears the entry can be blocked by a known protease inhibitor.
Interestingly, other early days studies available online posit that ACE2 is expressed in Asian males in higher concentrations than other race / gender combinations.
UncoverAg00 said:
Random thought... in the UK, don't they refer to their resumes as "CV"? Do you think that will change because of this?
"Do you have a CV?"
"No, I was just tested"
Resumes are usually 1 page. Curriculum Vitaes, CV's, are much longer and more detailed.
Assuming she is still alive, she would not stand a chance against CV.PJYoung said:Mr.Infectious said:
Presidential candidates needs to be its own category. Can you survive the primaries and CV?
Tulsi Gabbart is playing the long game waiting around for the old white dudes to fall. Smart girl. I'd put $20 on her for the long shot.
The English call all resumes CVs regardless of level of degree they have.TexasAggie_02 said:UncoverAg00 said:
Random thought... in the UK, don't they refer to their resumes as "CV"? Do you think that will change because of this?
"Do you have a CV?"
"No, I was just tested"
Resumes are usually 1 page. Curriculum Vitaes, CV's, are much longer and more detailed.
Our factory in Jiangsu province is back running but schools in Shanghai where most of the workers live (they drive in for the week and stay at dorms) are closed.
South Korea, a first world country, is being overrun. They have near 3,000 cases waiting for a hospital bed. Four have died waiting.rgag12 said:Marcus Aurelius said:
Do you think the NEJM is going to accept a bogus article for publication in their journal? I was in academics for a while and submitted a very good molecular genetics paper to them for publication re familial IPF and it was summarily rejected. Got it published in the AJRCCM. They have intense standards. The mortality data (1.4%) mirrors other recent publications. I think it's legit.
Some people on this thread are having a hard time coming to grips that the Coronavirus is very similar to other respiratory viruses, and is not as deadly to the general public as previously thought.
This is bad. I don't understand the absolute necessity of some of you to downplay this. ETA: Perhaps downplay is the wrong word, rather the need to mock those with concerns.
TexasAggie_02 said:UncoverAg00 said:
Random thought... in the UK, don't they refer to their resumes as "CV"? Do you think that will change because of this?
"Do you have a CV?"
"No, I was just tested"
Resumes are usually 1 page. Curriculum Vitaes, CV's, are much longer and more detailed.
CV (curriculum vitae) details peer-reviewed publications and the like.
My CV is 13 pages.
I wonder if that's in response to the economic impact and the need to get things going again or if that's a true indicator that they are starting to get this wrangled.
SK seems to be using hospitals as their containment centers whether or not the infected patients need hospitalization or not (instead of isolating the healthier infected at home or somewhere else). Not to downplay the scenario, SK has kind of created their own hospital room shortage by putting everyone in the hospital. Luckily the US seems to be learning from these mistakes as we've seen from attempts by WA state officials to isolate some patients in motels/hotels.Illuminaggie said:South Korea, a first world country, is being overrun. They have near 3,000 cases waiting for a hospital bed. Four have died waiting.rgag12 said:Marcus Aurelius said:
Do you think the NEJM is going to accept a bogus article for publication in their journal? I was in academics for a while and submitted a very good molecular genetics paper to them for publication re familial IPF and it was summarily rejected. Got it published in the AJRCCM. They have intense standards. The mortality data (1.4%) mirrors other recent publications. I think it's legit.
Some people on this thread are having a hard time coming to grips that the Coronavirus is very similar to other respiratory viruses, and is not as deadly to the general public as previously thought.
This is bad. I don't understand the absolute necessity of some of you to downplay this. ETA: Perhaps downplay is the wrong word, rather the need to mock those with concerns.
I read in their media that they are trying to do100% hospitalization as a containment measure. I think it's not working well - capacity isn't sufficient for the goal. But I don't think we can say they have that many people who *need* to be hospitalized clinically.
The virus would take one look at her and go, nope, no way, and promptly run in the opposite direction.Quote:
Assuming she is still alive, she would not stand a chance against CV.
"If you will not fight for right when you can easily win without blood shed; if you will not fight when your victory is sure and not too costly; you may come to the moment when you will have to fight with all the odds against you and only a precarious chance of survival. There may even be a worse case. You may have to fight when there is no hope of victory, because it is better to perish than to live as slaves." - Sir Winston Churchill
Still waiting on your answers.........Quote:
Some people on this thread are having a hard time coming to grips that the Coronavirus is very similar to other respiratory viruses, and is not as deadly to the general public as previously thought.
Illuminaggie said:South Korea, a first world country, is being overrun. They have near 3,000 cases waiting for a hospital bed. Four have died waiting.rgag12 said:Marcus Aurelius said:
Do you think the NEJM is going to accept a bogus article for publication in their journal? I was in academics for a while and submitted a very good molecular genetics paper to them for publication re familial IPF and it was summarily rejected. Got it published in the AJRCCM. They have intense standards. The mortality data (1.4%) mirrors other recent publications. I think it's legit.
Some people on this thread are having a hard time coming to grips that the Coronavirus is very similar to other respiratory viruses, and is not as deadly to the general public as previously thought.
This is bad. I don't understand the absolute necessity of some of you to downplay this. ETA: Perhaps downplay is the wrong word, rather the need to mock those with concerns.
So a 4 in 3, 000 rate = 0.1%...or about the same as the seasonal flu.
Seasonal flu is closer to .01%. And most of those 3,000 cases don't have outcomes yet. So, no.
No, four died waiting for a hospital bed. Right now they're 28 deaths, 5186 confirmed cases (851 new yesterday).
Average of averages of studies says ~17 days on average from symptom onset to death.
They also only have 34 recovered and 27 in serious or critical condition.
Average of averages of studies says ~17 days on average from symptom onset to death.
They also only have 34 recovered and 27 in serious or critical condition.
tehmackdaddy said:Illuminaggie said:South Korea, a first world country, is being overrun. They have near 3,000 cases waiting for a hospital bed. Four have died waiting.rgag12 said:Marcus Aurelius said:
Do you think the NEJM is going to accept a bogus article for publication in their journal? I was in academics for a while and submitted a very good molecular genetics paper to them for publication re familial IPF and it was summarily rejected. Got it published in the AJRCCM. They have intense standards. The mortality data (1.4%) mirrors other recent publications. I think it's legit.
Some people on this thread are having a hard time coming to grips that the Coronavirus is very similar to other respiratory viruses, and is not as deadly to the general public as previously thought.
This is bad. I don't understand the absolute necessity of some of you to downplay this. ETA: Perhaps downplay is the wrong word, rather the need to mock those with concerns.
So a 4 in 3, 000 rate = 0.1%...or about the same as the seasonal flu.
Death isn't the only endpoint that should be concerning. I don't know what SK's numbers are, but Chinese data report a very large proportion of those hospitalized suffering severe complications and requiring critical care for an extended duration. Even providing supportive care off site to those that aren't as severe is a sap on resources.
The mortality is probably not as damaging as the potential to overload critical systems. Awareness, preparation, and vigilance are a good thing. Coherent messaging from authorities that isn't dead wrong tomorrow would be too.
The fact that kids don't seem to get it and there are huge unknown numbers of asymptomatic folks I am guessing when we have better data after this initial season the death rate will be much closer to the flu.
"Fort Worth where the West begins...and Dallas is where the East peters out!"
It's weird everyone has this desire to draw an equivalence to the flu. I don't think there's evidence favoring that.
CDC says about half the people who have the flu go see a doctor, so the flu estimates for mortality are guessing that we only see half the cases.
But what's key, at least in my mind, is not the total number of cases and deaths. What's important, I think, is the comparison of the cases we see. In other words, if you're right that requires the range of outcomes to be much broader than the flu on both sides.
Hypothetically let's say SARS-CoV-2 has more mild cases than seasonal flu, and only 1% of people who get it go see the doc. That's what we "see" so the observed guesstimate of 1% mortality is really only 0.01%, same as the flu. Is that really better if the 1% that is going to see the doc are 20% severe, 5% requiring ICU? The flu doesn't have those numbers even considering the portion that we see.
CDC says about half the people who have the flu go see a doctor, so the flu estimates for mortality are guessing that we only see half the cases.
But what's key, at least in my mind, is not the total number of cases and deaths. What's important, I think, is the comparison of the cases we see. In other words, if you're right that requires the range of outcomes to be much broader than the flu on both sides.
Hypothetically let's say SARS-CoV-2 has more mild cases than seasonal flu, and only 1% of people who get it go see the doc. That's what we "see" so the observed guesstimate of 1% mortality is really only 0.01%, same as the flu. Is that really better if the 1% that is going to see the doc are 20% severe, 5% requiring ICU? The flu doesn't have those numbers even considering the portion that we see.
South Korea also has drive thru testing for this in all major cities, and is testing everyone with any sort of symptoms at all. They've also closed schools for the month of March, told people to work from home, canceled mass gatherings (concerts, sporting events, etc.), and basically told everyone to stay home to let it die out.
The CDC? Bungled the test kits, still trying to roll them out, and any doctor/ER who thinks they have an infected patient is having to call a CDC coronavirus hotline and ask for permission to refer the person for testing.
AND the CDC is only granting those under the idiotic, outdated criteria that the person traveled to China in the past month (as if anyone has at this point) or who has had close contact with someone who has been diagnosed with the infection.
We're still letting people travel in from other parts of Italy (as if corona is just limited to the Milan area or someone can't hop on a train). Still allowing travelers from the EU (despite cases in Italy, Spain, France, and the ease of travel from Italy to other EU nations). Still allowing people from Canada despite the outbreak there due to Iranian travel (and Trudeau not restricting travel from Iran to Canada).
Our national response is being led by a pack of idiots at the CDC.
The CDC? Bungled the test kits, still trying to roll them out, and any doctor/ER who thinks they have an infected patient is having to call a CDC coronavirus hotline and ask for permission to refer the person for testing.
AND the CDC is only granting those under the idiotic, outdated criteria that the person traveled to China in the past month (as if anyone has at this point) or who has had close contact with someone who has been diagnosed with the infection.
We're still letting people travel in from other parts of Italy (as if corona is just limited to the Milan area or someone can't hop on a train). Still allowing travelers from the EU (despite cases in Italy, Spain, France, and the ease of travel from Italy to other EU nations). Still allowing people from Canada despite the outbreak there due to Iranian travel (and Trudeau not restricting travel from Iran to Canada).
Our national response is being led by a pack of idiots at the CDC.
OK I will amend my statement to just we are way over estimating the death rate at this time, how about that?
"Fort Worth where the West begins...and Dallas is where the East peters out!"
https://www.google.com/amp/s/nypost.com/2020/03/03/bronx-jewish-day-school-closes-for-suspected-coronavirus-case/amp/
2nd confirmation in NY and some schools starting to close
2nd confirmation in NY and some schools starting to close
You may be end up being right, but not because of the characteristics of the coronavirus versus the flu.Agnzona said:
The fact that kids don't seem to get it and there are huge unknown numbers of asymptomatic folks I am guessing when we have better data after this initial season the death rate will be much closer to the flu.
The whole world is actively engaged in developing vaccines, drug treatments, and other measures to fight this disease. It remains to be seen if these can be developed and implemented in time to alleviate the effects in countries like SK, Italy, Iran, and the U.S.
Don't forget in middle east culture it is normal for men to kiss cheek to cheek, rub noses, and hold hands.bkag9824 said:tysker said:
23 more? Its as if the Iranian parliament is going around licking each others faces
Praying multiple times a day in very close proximity to a lot of other people miiiiight have something to do with it.
Right, but other than optimism what are you basing that on? Put another way, what is going to cause a significant shift in over / under reporting of minor cases? If there are cases that are so minor that people aren't going to see a doc (i.e., fever of <102 lasting a day or two - same as a minor case of the flu wouldn't prompt a doctor visit) why would they become reported in the future?
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