So, to be honest, I was a little concerned about my new Les Paul for a lack of... percussiveness? to the lower strings. They seemed to disappear when playing to the point that I had to raise the pickups a little on the low end side. Granted, the strings were obviously a little old and I don't know what brand.
Happy to say I finally got around to taking them off, cleaning/polishing the fretboard/frets, and setting the guitar up exactly how I like. Now those strings are nice and clear with a set of NYXL's. It's amazing what a new and good set of strings can do to your guitar, not to mention taking the time to properly set neck relief, string height, and intonation.
I always recommend the NYXL's to anyone who wants a good set of strings. Yeah, they're a little more expensive than others, but they last a LONG time and have such a great openess, clarity, and resonance across all 6 strings. I believe they really help bring out the tone of your guitar and I can go 6 months or more without replacing them on some of my less played guitars.