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Results
There were 159,560 participants aged 18 years and above not infected with COVID-19 prior to July 7, 2020, from the city of Itaja, Brazil. Among them, 45,716 (28.7%) did not use ivermectin and 113,844 (71.3%) used ivermectin prophylactically. Of the 113,844 participants, 8,325 (7.3%) subjects used ivermectin regularly and 33,971 (29.8%) used ivermectin irregularly. In total, 88,012 subjects were included in the present analysis. The 71,548 (62.8%) remaining participants used intermediate doses between 60 mg and 180 mg and were not included in this analysis.

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Correction
It has come to the attention of the journal that several authors failed to disclose all relevant conflicts of interest when submitting this article. As a result, Cureus is issuing the following erratum and updating the relevant conflict of interest disclosures to ensure these conflicts of interest are properly described as recommended by the ICMJ:

Lucy Kerr: Paid consultant for both Vitamedic, an ivermectin manufacturer, and Mdicos Pela Vida (MPV), an organization that promotes ivermectin as a treatment for COVID-19.

Flavio A. Cadegiani: Paid consultant ($1,600.00 USD) for Vitamedic, an ivermectin manufacturer. Dr. Cadegiani is a founding member of the Front Line COVID-19 Critical Care Alliance (FLCCC), an organization that promotes ivermectin as a treatment for COVID-19.

Pierre Kory: President and Chief Medical Officer of the Front Line COVID-19 Critical Care Alliance (FLCCC), an organization that promotes ivermectin as a treatment for COVID-19. Dr. Kory reports receiving payments from FLCCC. In February of 2022, Dr. Kory opened a private telehealth fee-based service to evaluate and treat patients with acute COVID, long haul COVID, and post-vaccination syndromes.

Jennifer A. Hibberd: Co-founder of the Canadian Covid Care Alliance and World Council for Health, both of which discourage vaccination and encourage ivermectin as a treatment for COVID-19.

Juan J. Chamie-Quintero: Contributor to the Front Line COVID-19 Critical Care Alliance (FLCCC) and lists the FLCCC as his employer on his LinkedIn page.

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The prevalence of intestinal parasitic infections (protozoa and/or helminths) in Brazil was 46% (confidence interval: 39-54%), with 99% heterogeneity.
...
CONCLUSIONS
The prevalence of intestinal parasitic infections is high in Brazil, and anthelmintic drugs should be administered periodically as a prophylactic measure, as recommended by the WHO.

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PerpetualLurker said:

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Why did they exclude a majority of ivermectin users? I couldn't find an explanation. Why wouldn't they show this data? They show irregular usage and no usage, but not this group.

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Results
There were 159,560 participants aged 18 years and above not infected with COVID-19 prior to July 7, 2020, from the city of Itaja, Brazil. Among them, 45,716 (28.7%) did not use ivermectin and 113,844 (71.3%) used ivermectin prophylactically. Of the 113,844 participants, 8,325 (7.3%) subjects used ivermectin regularly and 33,971 (29.8%) used ivermectin irregularly. In total, 88,012 subjects were included in the present analysis. The 71,548 (62.8%) remaining participants used intermediate doses between 60 mg and 180 mg and were not included in this analysis.

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Recommendation
The Panel recommends against the use of ivermectin for the treatment of COVID-19, except in clinical trials ().

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fullback44 said:

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PerpetualLurker said:

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Why did they exclude a majority of ivermectin users? I couldn't find an explanation. Why wouldn't they show this data? They show irregular usage and no usage, but not this group.

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Results
There were 159,560 participants aged 18 years and above not infected with COVID-19 prior to July 7, 2020, from the city of Itaja, Brazil. Among them, 45,716 (28.7%) did not use ivermectin and 113,844 (71.3%) used ivermectin prophylactically. Of the 113,844 participants, 8,325 (7.3%) subjects used ivermectin regularly and 33,971 (29.8%) used ivermectin irregularly. In total, 88,012 subjects were included in the present analysis. The 71,548 (62.8%) remaining participants used intermediate doses between 60 mg and 180 mg and were not included in this analysis.

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Then why did the NIH recently add ivermectin as a medicine that is now approved to treat covid?

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Hoosegow said:

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Just got sick a heck. Deep cough. Started the FLCCC ivermectin protocol yesterday. No fever today. Cough is a lot better. And no, I'm not dumb enough to get tested. But... tonight, my cough is almost gone. I only feel a little bit sick.

Completely anecdotal, but I felt a lot better about 4 hours taking my first dose of Ivermectin and damn near feel normal after my second.

And then again it all could be the pseudo effect

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Samuel Bankman-Fried's bankrupt and scandal-plagued cryptocurrency empire gave $18.25 million to early COVID-19 researchers whose findings cast doubt on the benefits of ivermectin and hydroxychloroquine for patients with COVID-19.
The FTX Foundation provided initial funding worth $3.25 million and followed it with another $15 million grant, according to a press release issued May 16.
"The FTX Foundation is excited to commit $15 million to funding additional trial arms in the TOGETHER Trial and its growing global network of sister trials," said Ross Rheingans-Yoo, from the FTX Foundation.
"Our initial $3.25 million grant to expand the trial network's core infrastructure has helped bring the model from Brazil to key sites across the globe, and we look forward to finding further opportunities to support the consortium's growth and help prevent future pandemics," he said.
Together Trial's research included a study that found ivermectin's benefits for patients suffering from COVID-19 were unclear and a study that concluded hydroxychloroquine did not show any benefit in decreasing hospitalizations. Both studies were influential amid debates over the use of conventional, inexpensive treatments as opposed to expensive mRNA injections developed by the large pharmaceutical companies, like Pfizer, Moderna, and Johnson & Johnson.

Both drugs were floated early in the pandemic as potential treatments for those suffering from the virus, but they quickly became politically polarizing when they received support from President Donald Trump and podcaster Joe Rogan. Mainstream physicians and the media raced to discredit the cheap, safe drugs that have been used for decades for a host of other diseases. Both of these studies were led by Dr. Gilmar Reis.

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Guardian Angel said:

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Ivermectin and HCQ always worked

Bankrupt FTX Gave $18.2M to Early COVID-19 Researchers Who Cast Doubt on Ivermectin and Hydroxychloroquine

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Samuel Bankman-Fried's bankrupt and scandal-plagued cryptocurrency empire gave $18.25 million to early COVID-19 researchers whose findings cast doubt on the benefits of ivermectin and hydroxychloroquine for patients with COVID-19.
The FTX Foundation provided initial funding worth $3.25 million and followed it with another $15 million grant, according to a press release issued May 16.
"The FTX Foundation is excited to commit $15 million to funding additional trial arms in the TOGETHER Trial and its growing global network of sister trials," said Ross Rheingans-Yoo, from the FTX Foundation.
"Our initial $3.25 million grant to expand the trial network's core infrastructure has helped bring the model from Brazil to key sites across the globe, and we look forward to finding further opportunities to support the consortium's growth and help prevent future pandemics," he said.
Together Trial's research included a study that found ivermectin's benefits for patients suffering from COVID-19 were unclear and a study that concluded hydroxychloroquine did not show any benefit in decreasing hospitalizations. Both studies were influential amid debates over the use of conventional, inexpensive treatments as opposed to expensive mRNA injections developed by the large pharmaceutical companies, like Pfizer, Moderna, and Johnson & Johnson.

Both drugs were floated early in the pandemic as potential treatments for those suffering from the virus, but they quickly became politically polarizing when they received support from President Donald Trump and podcaster Joe Rogan. Mainstream physicians and the media raced to discredit the cheap, safe drugs that have been used for decades for a host of other diseases. Both of these studies were led by Dr. Gilmar Reis.

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Among outpatients with mild or moderate COVID-19, treatment with ivermectin, with a targeted maximum dose of 600 g/kg daily for 6 days, was not shown to improve time to sustained recovery compared with placebo. These findings do not support the use of ivermectin in outpatients with COVID-19.

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