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Spike protein inhibits DNA repair
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Last: 3 yr ago by Ranger222
So we all eventually die anyway.
Wait wasn't that true before the pandemic?
Wait wasn't that true before the pandemic?
No way this virus wasn't man made.
"Our findings reveal a potential molecular mechanism by which the spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines."
"This suggests that the use of antigenic epitopes of the spike as a SARSCoV2 vaccine might be safer and more efficacious than the fulllength spike. Taken together, we identified one of the potentially important mechanisms of SARSCoV2 suppression of the host adaptive immune machinery. Furthermore, our findings also imply a potential side effect of the fulllength spikebased vaccine. This work will improve the understanding of COVID19 pathogenesis and provide new strategies for designing more efficient and safer vaccines."
Seems sort of contradicting.
I feel like the more info that is out there, the more of a wash it is for the young and healthy to get the shot until a few more years.
"This suggests that the use of antigenic epitopes of the spike as a SARSCoV2 vaccine might be safer and more efficacious than the fulllength spike. Taken together, we identified one of the potentially important mechanisms of SARSCoV2 suppression of the host adaptive immune machinery. Furthermore, our findings also imply a potential side effect of the fulllength spikebased vaccine. This work will improve the understanding of COVID19 pathogenesis and provide new strategies for designing more efficient and safer vaccines."
Seems sort of contradicting.
I feel like the more info that is out there, the more of a wash it is for the young and healthy to get the shot until a few more years.
So the virus is bad for us, and the vaccine is bad for us? Is that what this paper says?
I am no scientist, but anything that inhibits DNA repair (they are saying both virus and jab do here) seems very bad. Is this permanent or just temporary or what? It would seem that if this applies to humans at large, outside of laboratory petri dishes, that cases of cancer and other deadly illnesses would potentially skyrocket in the coming years if DNA cannot repair itself.snowdog90 said:
So the virus is bad for us, and the vaccine is bad for us? Is that what this paper says?
I am hoping someone with more scientific credentials than me can come on here and explain how this is nothig to worry about.
Are we now finding out why the lockdowns and nonsense for 1.5 years over a virus that has a 99.97% survival rate? This has been by concern along that this thing is 100% fatal..it only take a little longer.
My key takeaway was:Quote:
So the virus is bad for us, and the vaccine is bad for us? Is that what this paper says?
Seems to be saying certain patients with severe cases do not develop an adaptive immune response and the reason for that was a mystery. The author is trying to explain away that mystery with his theory that the spike protein inhibits the DNA Repair process that is part of the process that allow the adaptive immune system to add this bug to its hit list.Quote:
Clinical studies have indicated that patients with severe COVID19 exhibit delayed and weak adaptive immune responses; however, the mechanism by which SARSCoV2 impedes adaptive immunity remains unclear. Here, by using an in vitro cell line, we report that the SARSCoV2 spike protein significantly inhibits DNA damage repair, which is required for effective V(D)J recombination in adaptive immunity.
The author then goes on to theorize that the type of spike protein used in the vaccination process should be considered given this fact and says we should tweak the process of vaccine design to ensure maximum adaptive immune response.
This really shouldn't be a surprise - it's what viruses do. And it's more prevalent in RNA viruses - which include coronavirus, HIV, and Hep C.
They have to hijack healthy cells in order to replicate. Over the long term, that can cause damage to our cells. Think the HPV virus and cervical cancer or Hep C and liver, head, and neck cancers.
If you have insomnia tonight, you can take a look at this article from 2016.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808796/
They have to hijack healthy cells in order to replicate. Over the long term, that can cause damage to our cells. Think the HPV virus and cervical cancer or Hep C and liver, head, and neck cancers.
If you have insomnia tonight, you can take a look at this article from 2016.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808796/
This post sure isn't getting much traction here. I wonder if those that believe in "science" are ****ting their pants.
Is the survival rate of stomach cancer less than covid?
Is the survival rate of stomach cancer less than covid?
Boo Weekley said:I am no scientist, but anything that inhibits DNA repair (they are saying both virus and jab do here) seems very bad. Is this permanent or just temporary or what? It would seem that if this applies to humans at large, outside of laboratory petri dishes, that cases of cancer and other deadly illnesses would potentially skyrocket in the coming years if DNA cannot repair itself.snowdog90 said:
So the virus is bad for us, and the vaccine is bad for us? Is that what this paper says?
I am hoping someone with more scientific credentials than me can come on here and explain how this is nothig to worry about.
Easy enough. Even if the spike protein inhibits DNA repair, which isn't definitely proven by this study btw, it's still not a problem. The vaccine causes you to produce spike proteins for about a day, and those spike proteins hang around a few weeks. That's nothing on a cancer time-scale, so it would be very surprising if either the virus or the vaccine caused any noticeable increase in cancer.
All the viral-related cancers I can recall involve much longer infections. Things like HPV, HIV, hep c and the like are present for years. Now EBV lasts weeks and increases risk for cancer, but it does it in a completely unique way that has nothing to do with COVID
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
I think this is the biggest misunderstanding over on F16 and elsewhere. Lots of folks have convinvned themselves that the vaccine keeps generating spike proteins for long periods and there is some big shoe to drop.Quote:
The vaccine causes you to produce spike proteins for about a day, and those spike proteins hang around a few weeks.
For example from our friends on the other forum.
Quote:
"One of the bad effects of the mRNA vaccines, I think, is that there has not been testing (too my knowledge) of how long cells keep pumping out spike proteins. If there are some cells that keep feeding your system the spike for a long time, it could seriously impact your immune system."
"With mRNA or adeno viruses, your cells are making the spike protein. Scientists think they have a pretty good idea of how much spike protein your body will make and how long that function will stay around, but I still haven't seen any long term tests."
"But with Novavax, you're just introducing your body to the spike protein (ie extremely small sample of it, which your body learns to defeat).
With mRNA, your body is producing it. It has a much bigger presence.
As I read it, It's like comparing a single glass of water which dries up, to a lake that's constantly being filled up"
"I have seen studies that suggests the vaccine keeps "working" long past when they should, which would be bad.
This is bad because you have a chance to not catch covid, but with the vaccine it looks like you are guaranteeing DNA damage. So yes, I will take a victory dance."
ramblin_ag02 said:Boo Weekley said:I am no scientist, but anything that inhibits DNA repair (they are saying both virus and jab do here) seems very bad. Is this permanent or just temporary or what? It would seem that if this applies to humans at large, outside of laboratory petri dishes, that cases of cancer and other deadly illnesses would potentially skyrocket in the coming years if DNA cannot repair itself.snowdog90 said:
So the virus is bad for us, and the vaccine is bad for us? Is that what this paper says?
I am hoping someone with more scientific credentials than me can come on here and explain how this is nothig to worry about.
Easy enough. Even if the spike protein inhibits DNA repair, which isn't definitely proven by this study btw, it's still not a problem. The vaccine causes you to produce spike proteins for about a day, and those spike proteins hang around a few weeks. That's nothing on a cancer time-scale, so it would be very surprising if either the virus or the vaccine caused any noticeable increase in cancer.
All the viral-related cancers I can recall involve much longer infections. Things like HPV, HIV, hep c and the like are present for years. Now EBV lasts weeks and increases risk for cancer, but it does it in a completely unique way that has nothing to do with COVID
This. I should have edited my post to clarify.
The viruses that cause long-term damage are ones that stay in our bodies for a long time. If you contract Hep C or HIV, there is no cure - you are infected forever (the virus may or may not be dormant).
Based on what we know now, our bodies are capable of clearing Covid. Meaning, at some point after infection, you test negative. Doesn't mean you won't get reinfected, but hasn't been shown to be a virus that stays in the body.
My bigger point, though, was that viruses cause disruption of our DNA. That's how all viruses replicate.
I think if people fundamentally understood that, this whole situation would be a lot less frightening.
Agree, but just nitpicking to say that HepC is curable now!
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
The more info that comes out, the more I'm convinced I made the right decision. I got covid and took the treatments. I will likely contract it again.
ramblin_ag02 said:
Agree, but just nitpicking to say that HepC is curable now!
I didn't know that! Thanks for correcting me.
Robin Hood Was A Thief said:
This post sure isn't getting much traction here. I wonder if those that believe in "science" are ****ting their pants.
Is the survival rate of stomach cancer less than covid?
People on this forum basically ignore anything posted by the OP. He and petebaker are the number one source vaccine misinformation on this website. There's not point engaging.
This study is in vitro. Don't read into it too much. Plenty of things work one way in vitro and a different way in vivo. Needs more investigation.
I doesn't help that he ran over here on a ban bet from another F16 poster.Quote:
People on this forum basically ignore anything posted by the OP. He and petebaker are the number one source vaccine misinformation on this website. There's not point engaging.
https://texags.com/forums/16/topics/3249514
Rapier108
11:33a, 11/15/21
Post this on F84 and see how long your ban would be.
baron_von_awesome
In reply to Rapier108 11:35a, 11/15/21
On itQuote:
Rapier108 said:
Post this on F84 and see how long your ban would be.
ramblin_ag02 said:
Agree, but just nitpicking to say that HepC is curable now!
Ehhhhh....herpes and ebv would like to have a word with you. Im outta my lane here, but I believe there are numerous viruses that create latent reservoirs that would not be detected in a test.
Edit to add HPV....it's very widespread, most people suppress most forms of it after the initial infection, but it's certainly there.
A few weeks? Hopefully not as in like two weeks to flatten the curve. I'm sure they are diligently and transparently tracking this and definitely not silencing any evidence otherwise.
FYI -- MDPI is a horrible publisher / journal system that does very little, if any peer review.
Would not take any publication from any of those journals seriously.
Would not take any publication from any of those journals seriously.
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