Both from native virus and the jab.

https://www.mdpi.com/1999-4915/13/10/2056/htm

Quote:

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Our findings provide evidence of the spike protein hijacking the DNA damage repair machinery and adaptive immune machinery in vitro. We propose a potential mechanism by which spike proteins may impair adaptive immunity by inhibiting DNA damage repair. Although no evidence has been published that SARSCoV2 can infect thymocytes or bone marrow lymphoid cells, our in vitro V(D)J reporter assay shows that the spike protein intensely impeded V(D)J recombination. Consistent with our results, clinical observations also show that the risk of severe illness or death with COVID19 increases with age, especially older adults who are at the highest risk [22]. This may be because SARSCoV2 spike proteins can weaken the DNA repair system of older people and consequently impede V(D)J recombination and adaptive immunity. In contrast, our data provide valuable details on the involvement of spike protein subunits in DNA damage repair, indicating that fulllength spikebased vaccines may inhibit the recombination of V(D)J in B cells, which is also consistent with a recent study that a fulllength spikebased vaccine induced lower antibody titers compared to the RBDbased vaccine [28]. This suggests that the use of antigenic epitopes of the spike as a SARSCoV2 vaccine might be safer and more efficacious than the fulllength spike. Taken together, we identified one of the potentially important mechanisms of SARSCoV2 suppression of the host adaptive immune machinery. Furthermore, our findings also imply a potential side effect of the fulllength spikebased vaccine. This work will improve the understanding of COVID19 pathogenesis and provide new strategies for designing more efficient and safer vaccines.

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baron_von_awesome said:

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I think the Novavax vaccine that is coming would be free from this 'unexpected' side effect.

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Is this facetious?

Novavax IS the spike protein. Why wouldn't Novavax cause this side effect, at least for a while.

BusterAg said:

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baron_von_awesome said:

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I think the Novavax vaccine that is coming would be free from this 'unexpected' side effect.

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Is this facetious?

Novavax IS the spike protein. Why wouldn't Novavax cause this side effect, at least for a while.

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I dont know, would it?

BusterAg said:

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baron_von_awesome said:

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I think the Novavax vaccine that is coming would be free from this 'unexpected' side effect.

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Is this facetious?

Novavax IS the spike protein. Why wouldn't Novavax cause this side effect, at least for a while.

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Wouldn't that mean lots of similar vaccines also have the same problem then?

BusterAg said:

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baron_von_awesome said:

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I think the Novavax vaccine that is coming would be free from this 'unexpected' side effect.

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Is this facetious?

Novavax IS the spike protein. Why wouldn't Novavax cause this side effect, at least for a while.

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I was thinking about MAYBE getting Novavax at some point, so it was more wishful thinking than being facetious I guess.

Post this on F84 and see how long your ban would be.

Hope this isn't true.

not jabbed, but got seriously ill from Covid. so that is just as bad to long term health issues as the vax if i read this correctly?

Rapier108 said:

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Post this on F84 and see how long your ban would be.

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On it

BusterAg said:

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baron_von_awesome said:

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I think the Novavax vaccine that is coming would be free from this 'unexpected' side effect.

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Is this facetious?

Novavax IS the spike protein. Why wouldn't Novavax cause this side effect, at least for a while.

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There is a difference though...in that your body isnt producing it. With the Novavax introduces yoru body to it, which then builds defenses against it.

I'd think that's different than teaching your body to make it, and then having your body attack what it's making (mRNA).

Ok, cliff notes for the reading comprehension impaired.

Jab good or bad long term?

AgGrad99 said:

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BusterAg said:

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baron_von_awesome said:

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I think the Novavax vaccine that is coming would be free from this 'unexpected' side effect.

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Is this facetious?

Novavax IS the spike protein. Why wouldn't Novavax cause this side effect, at least for a while.

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There is a difference though...in that your body isnt producing it. With the Novavax introduces yoru body to it, which then builds defenses against it.

I'd think that's different than teaching your body to make it, and then having your body attack what it's making (mRNA).

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Well, yeah, that has been my position all along.

Here is my understanding, happy to be corrected if someone knows more than me:

1) The spike protein itself interrupts DNA repair, which would help with adaptive immunity (being immune to more than one strain of the virus) and just general immune function.

2) With Novavax, you know how long the protein is likely going to hang around in your body. Also, there is a set amount of it. You inject it, and when your immune system eliminates it, there is no more spike protein in your body.

3) With mRNA or adeno viruses, your cells are making the spike protein. Scientists think they have a pretty good idea of how much spike protein your body will make and how long that function will stay around, but I still haven't seen any long term tests.

4) But, if the spike protein is the one interrupting DNA repair, I think that even Novavax would impair immune functions for a couple of weeks to a couple of months.

But with Novavax, you're just introducing your body to the spike protein (ie extremely small sample of it, which your body learns to defeat).

With mRNA, your body is producing it. It has a much bigger presence.

As I read it, It's like comparing a single glass of water which dries up, to a lake that's constantly being filled up.

BusterAg said:

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baron_von_awesome said:

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I think the Novavax vaccine that is coming would be free from this 'unexpected' side effect.

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Is this facetious?

Novavax IS the spike protein. Why wouldn't Novavax cause this side effect, at least for a while.

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it says this;

indicating that full length spike based vaccines may inhibit the recombination of V(D)J in B cells




is Novavax full length?

Any difference with the J&J vaccine?

FriscoKid said:

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Any difference with the J&J vaccine?

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Yes, very curious on this as well.

baron_von_awesome said:

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BoDog said:

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Ok, cliff notes for the reading comprehension impaired.

Jab good or bad long term?

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Bad, that's why it was stupid to skip 6-10 years of long term safety studies.

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Sort of, potentially.

Both the virus and the vaccine have this property. So, getting the virus (i.e. "natural immunity") would have the same impact as getting the vaccine with regard to this activity.

There is no "victory dance" to be done by either "side" here. The only people that this won't impact are people that never get the current vaccines and never get or get exposed to the virus.

I don't know how many people that will eventually actually be (I would bet a somewhat small number, but that is a completely uneducated, wild-ass guess).

All of which assumes that the lab experiments bear out in actual humans, and I have no idea how likely or unlikely that is.

Bottom line is that this is a "feature" of the virus, not the vaccines.

The research may lead to a better (safer) vaccine that does not have this "feature" of the virus.

NOTE: all of the above is from a layman's reading of the study results linked in the OP. I am not in any way, shape or form a scientist, doctor or medical professional, nor do I claim to be. I could be completely off base.

Here is a video I watched a couple days ago that explains it.

CCP Joe Veggie said:

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BusterAg said:

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baron_von_awesome said:

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I think the Novavax vaccine that is coming would be free from this 'unexpected' side effect.

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Is this facetious?

Novavax IS the spike protein. Why wouldn't Novavax cause this side effect, at least for a while.

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it says this;

indicating that full length spike based vaccines may inhibit the recombination of V(D)J in B cells




is Novavax full length?

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This is a good question.

Novavax is a protein sub-unit vaccine, but that doesn't mean that the Novavax spike was doesn't include the entire spike.

Would have to look carefully. Don't have time to now.

Quote:

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3) With mRNA or adeno viruses, your cells are making the spike protein. Scientists think they have a pretty good idea of how much spike protein your body will make and how long that function will stay around, but I still haven't seen any long term tests.

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So having a jab ever 4-6 months would be just adding gasoline to the fire ? ? ?