44mAG
LoDo is fine before midnight; after midnight you can find trouble if you're looking for it just like any downtown. There are definitely more homeless people downtown than in Aggieland. Wife and I go out in LoDo around Union Station, Larimer Street between 14 and 15th, and several areas in Uptown. Steubens is a very cool restaurant in Uptown on 17th, and it's right next to ACE which is also a cool restaurant and ping pong hall; both have great food, drinks, vibe, and people watching. Again, if you're over 40, she'll like Cherry Creek more and if you're under 40 she'll like Lower Highlands more; see prior posts for specifics.
Counterpoint
Ralphie will run; and it's an awesome sight.
I'm sitting in the shade on my front patio, it's 85 and it feels perfect, almost chilly out of the sun. Low humidity is a thing. Pack a light jacket to wear in the evenings when it cools down. Sun is also a thing here; it's intense so sunscreen, sunglasses, and a hat for the game is no joke.