China Coronavirus Outbreak Spreads; Hundreds Infected As Human-To-Human Transmission

3,235,172 Views | 21764 Replies | Last: 2 mo ago by Stat Monitor Repairman
scottimus
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Here it is...
jpd301
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Chinese doctors say coronavirus 'like a combination of SARS and AIDS', can cause irreversible lung damage
Quote:

Chinese doctors say autopsies of coronavirus victims suggest the deadly illness is "like a combination of SARS and AIDS" that can cause "irreversible" lung damage even if the patient recovers.

The grim finding was reported on by Communist Party mouthpiece the Global Times on Friday, after a paper by Wuhan doctors published in the Journal of Forensic Medicine earlier in the week went viral on Chinese social media.

"The influence of COVID-19 on the human body is like a combination of SARS and AIDS as it damages both the lungs and immune systems," Peng Zhiyong, director of the intensive care unit of the Zhongnan Hospital of Wuhan University in Wuhan, told the Global Times.


More info in the article
scottimus
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That has definitely been a topic of conversation on this thread. Raises a lot questions.
scottimus
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Notre Dame Brings Back 106 Faculty and Staff from Italy....Told to quarantine for 14 days....

How many is A&M bringing back?

https://www.wndu.com/content/news/ND-student-speaks-about-leaving-Italy-due-to-coronavirus-568492641.html?fbclid=IwAR07sL7v7NhSMioILyQfmf0PkXhPJSFeSCuCdBf2V9E65LemUkLrwBSAYvA

Quote:

NOTRE DAME, Ind. (WNDU) - More than 100 University of Notre Dame students have made it safely out of Italy, where the coronavirus cut short their study abroad program.

University officials say most of the 106 students arrived stateside on Sunday, while the last trickled in on Tuesday.

Notre Dame junior Jennifer Trzaska was wearing a smile instead of a mask in the picture she took in Italy the day before she and her classmates returned home.
"I wouldn't say scared is the right word; tensions were definitely higher just in general around the city. They were doing a lot of, like, industrial cleaning through the city, so there were areas that were kind of just like reeked of rubbing alcohol, which I think was the worst part," Trzaska said in a phone interview with 16 News Now.

Trzaska says things in Italy have since become worse and she's relatively glad to be back at her family home in Ohio, riding out a mandated two-week quarantine for spending seven memorable months in Italy.

"During these two weeks I'm just kind of hanging out and, you know, listening to my siblings having fun from the other room, a lot of passing notes under doors and, yeah, binge-watching TV," Trzaska said.



jagvocate
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SARS and AIDS?

We had an article about this being weaponized and showing gene sequences with HIV pretty early on this journey and it was fairly roundly dismissed.

aild246
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I have nothing to contribute if not maybe a bit of levity.

scottimus
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Lol, Is that Billy Bob's son or what?
bmks270
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Nuclear Scramjet said:

https://www.thegatewaypundit.com/2020/03/breaking-report-congressional-staffer-tests-positive-for-coronavirus/

Congressional staffer diagnosed with it. Also lots may have been exposed at AIPAC.


Senate must be freaking out.
flakrat
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I hope that's an Arkansas fan!
scottimus
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San Jose pulling a China...

https://sanfrancisco.cbslocal.com/2020/03/04/coronavirus-san-jose-good-samaritan-hospital-surge-tents-influx-cases-covid19/?fbclid=IwAR0MkWT5KjnP3lJQpAPjSm6R3ttfORgILmgczvKvVJcSMoyiqNefM2_SG5o

Quote:

SAN JOSE (KPIX 5) Good Samaritan Hospital in San Jose is prepping "surge tents" to handle a possible influx of coronavirus cases.



The tan-colored tents are currently erected on the southern border of the hospital's property, facing Samartian Drive, directly adjacent to the emergency room's paramedic entrance and the public sidewalk.

The footprint of the two identical structures measures 15 feet by 30 feet and stands about 10 feet tall in the center. Each one is large enough to handle up to six patients at a time while still allowing the minimum "six foot exclusion zone," the distance

health officials say is sufficient to prevent human-to-human transmission of the disease.
"To keep them safe and make sure they are not co-mingling together," said Mark Brown, Chief Nursing Officer for Good Samaritan Hospital.

The surge tents, which are owned by the hospital, are typically brought out during flu season. But Brown pushed to erect the tents early in light of the steady increase of COVID-19 cases in the Bay Area.

"We're taking an overabundance of caution to do the right thing, and we feel for our patient population and for our community, this is the best way to serve them," said Brown.
Diyala Nick
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Fairview said:

Total dick move.




Jerry of the day!!!
lead
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scottimus said:

San Jose pulling a China
more like San Jose pulling a San Jose
Quote:

The surge tents, which are owned by the hospital, are typically brought out during flu season. But Brown pushed to erect the tents early....
Cancelled
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claym711
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queso1 said:




So by this logic the mortality rate for seasonal flu is what like .001%?
unmade bed
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jpd301 said:

Chinese doctors say coronavirus 'like a combination of SARS and AIDS', can cause irreversible lung damage
Quote:

Chinese doctors say autopsies of coronavirus victims suggest the deadly illness is "like a combination of SARS and AIDS" that can cause "irreversible" lung damage even if the patient recovers.

The grim finding was reported on by Communist Party mouthpiece the Global Times on Friday, after a paper by Wuhan doctors published in the Journal of Forensic Medicine earlier in the week went viral on Chinese social media.

"The influence of COVID-19 on the human body is like a combination of SARS and AIDS as it damages both the lungs and immune systems," Peng Zhiyong, director of the intensive care unit of the Zhongnan Hospital of Wuhan University in Wuhan, told the Global Times.


More info in the article


Quote from article below doesn't jive with sensational headline:

Quote:

"However, since the natural history of COVID-19 pneumonia is yet to be fully explored, it is too early to label these lung changes as irreversible fibrosis," the researchers wrote.
n_touch
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Vendor who sold concessions at Seattle XFL game tests positive for coronavirus

Quote:

A vendor who sold concessions at CenturyLink Field during the February 22 Seattle Dragons XFL game has tested positive for COVID-19, but authorities say it is unlikely the stadium employee spread the coronavirus to anyone at the game.

"We have worked with the employee and the operator of the stadium, First and Goal, to evaluate potential exposures at the Feb. 22 Seattle Dragons game, and we've determined that the risk of infection to attendees from this person was low," a spokesman for Seattle's public health department told the Seattle Times. "We are following up with a few co-workers with close contacts of the employee at the February 22nd game to provide guidance on appropriate precautions"
Snap E Tom
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IrishTxAggie said:

OldArmy71 said:

I don't understand how Israel and other countries can say they are about to produce a vaccine and the US says 12-18 months.


They don't have to follow our FDA protocol. Ultimately, I wonder if Trump could/would use an executive order to fast track after a successful P1 and P2 instead of waiting for a P3 trial.
Hmmm... COVID-19 or flipper babies, COVID-19 or flipper babies.... Tough choice.
Hogties
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claym711 said:

queso1 said:




So by this logic the mortality rate for seasonal flu is what like .001%?

No. What Brett is saying in the clip is that you can't simply do the math of reported COVID19 deaths divided by confirmed positive cases of COVID19 and give a death rate because many cases of COVID19 are not counted because they are relatively benign and don't get tested.

The numbers of US flu hospitalizations and deaths and death rate for seasonal flu is an estimated number based on modeling. It is not based only on actual reported seasonal flu illness and deaths. It is a model that tries to account for under reporting of flu and extrapolate out to the population. So the estimate of seasonal flu at .1% death rate is based on modeled numbers, not actual seasonal flu reporting. So CDC already is accounting for the unreported positive seasonal flu cases in their numbers.

https://www.cdc.gov/flu/about/burden/how-cdc-estimates.htm

There's not enough data to fully model COVID19, but Brett is cautioning the media to not simply do the math of reported actual COVID19 deaths divided by actual reported positive COVID19 cases because you will miss a large number of people who had COVID19 but were never tested and therefore aren't accounted for in the reported numbers. That's the denominator problem, as he put it.

What he is saying is that doing a death rate estimate using only actual numbers will overestimate the fatality rate. You can't simply say - The worldwide toll as of 2:30 am on March 6 is 98,436 confirmed cases and 3,387 deaths therefore the fatality rate is 3.4%. That would greatly overestimate the death rate because many infected people will never be positively tested for COVID19 even though they had it.

StrickAggie06
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Rapier108 said:

Guy and his female "partner" return to New Zealand from, where else, northern Italy. While sick he goes to a freaking rock concert.

https://www.nzherald.co.nz/nz/news/article.cfm?c_id=1&objectid=12314491

I swear, stupid people are more dangerous than a nuclear bomb.

Son of a *****! I'm leaving for Auckland TODAY. New Zealand was supposed to stay nice and safe!
StrickAggie06
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cisgenderedAggie said:

flakrat said:

What type of equipment and personnel are needed to perform the tests (re: the post by Abbott about Texas being able to do 125 per day once things are ramped up)?

I'm wondering if this equipment and personnel are mostly located in research universities here in the states and the process of pooling all of those resources in a system like ours might be insanely difficult and time consuming compared to doing the same in a small country like South Korea where (assumption) the facilities and personnel all report to the federal government?

I.e. stop all research and other work you are doing on that equipment and run COVID-19 tests 24x7
  • USA Researcher: Da***?
  • SK Researcher: Whatever you say, boss!



I don't understand the throughput issues. These are supposed be quantitative RT-PCR assays and the equipment is pretty standard in a modern molecular biology lab. I've never used a machine that couldn't run at least 96 reactions at a time and a run probably doesn't take longer than 3 hrs from setup to results. Assuming their running 5 replicates for positive and negative controls and each test, there should be room for 10-15 tests for each 96 well run.

Every research university in the state probably has at least a dozen machines for this, but the lab space and maintenance might not be up to specs. All short term problems for an emergency.

I was wondering the same thing. In graduate school at A&M, we had a 386 well plate rt-PCR machine. Just by myself, I could run 160-240 tests per day, assuming the same number of replicates you mentioned.

That's one machine, in one lab, run by one person. And the most the entire state of Texas can do is 125 per day? Makes zero sense, even if you consider competing research demand for the machines and labor.
joerobert_pete06
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Looks like two Microsoft employees have contracted the coronavirus, it is for sure coming to my building now

https://www.cnbc.com/2020/03/06/microsoft-says-two-employees-have-been-diagnosed-with-coronavirus.html
Quote:

Two Microsoft employees in Washington state have contracted the coronavirus.
They are among the more than 95,000 COVID-19 cases around the globe, according to the World Health Organization.

Both employees are located in Puget Sound, the area that includes Microsoft's Redmond headquarters, a Microsoft spokesperson told CNBC in an email on Thursday evening. One is an employee of Microsoft subsidiary LinkedIn who works remotely, a LinkedIn spokesperson told CNBC in an email.
"Local health experts have determined that this individual had no known contact with other employees while infected and, based on that fact, there is no risk to those who work at LinkedIn from this case," the LinkedIn spokesperson wrote. "We are doing everything we can to support our colleague and will continue to keep the health and safety of our employees, customers and partners as our top priority, working closely with public health officials globally."
On Wednesday, Microsoft instructed employees in the Puget Sound and California's Bay Area to work from home if they can over the next few weeks. The company also limited employee travel.
On the same day, Facebook said a contractor based at one of the company's offices in Seattle tested positive for the virus.
gonemaroon
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jpd301 said:

Chinese doctors say coronavirus 'like a combination of SARS and AIDS', can cause irreversible lung damage
Quote:

Chinese doctors say autopsies of coronavirus victims suggest the deadly illness is "like a combination of SARS and AIDS" that can cause "irreversible" lung damage even if the patient recovers.

The grim finding was reported on by Communist Party mouthpiece the Global Times on Friday, after a paper by Wuhan doctors published in the Journal of Forensic Medicine earlier in the week went viral on Chinese social media.

"The influence of COVID-19 on the human body is like a combination of SARS and AIDS as it damages both the lungs and immune systems," Peng Zhiyong, director of the intensive care unit of the Zhongnan Hospital of Wuhan University in Wuhan, told the Global Times.


More info in the article

I keep being told by internet geniuses that this is no worse than the common flu - personally I cannot afford to get irreversible damage to my body. Hopefully in 2-3 weeks they will have more data - either good or bad. Until then I am laying low, and will re-evaluate then. There's too much good and bad information coming out to know what's fact - every government has their own agenda at this point.
Stat Monitor Repairman
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Definitely something off about how all this is playing out.
IDAGG
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Hogties said:

claym711 said:

queso1 said:




So by this logic the mortality rate for seasonal flu is what like .001%?

No. What Brett is saying in the clip is that you can't simply do the math of reported COVID19 deaths divided by confirmed positive cases of COVID19 and give a death rate because many cases of COVID19 are not counted because they are relatively benign and don't get tested.

The numbers of US flu hospitalizations and deaths and death rate for seasonal flu is an estimated number based on modeling. It is not based only on actual reported seasonal flu illness and deaths. It is a model that tries to account for under reporting of flu and extrapolate out to the population. So the estimate of seasonal flu at .1% death rate is based on modeled numbers, not actual seasonal flu reporting. So CDC already is accounting for the unreported positive seasonal flu cases in their numbers.

https://www.cdc.gov/flu/about/burden/how-cdc-estimates.htm

There's not enough data to fully model COVID19, but Brett is cautioning the media to not simply do the math of reported actual COVID19 deaths divided by actual reported positive COVID19 cases because you will miss a large number of people who had COVID19 but were never tested and therefore aren't accounted for in the reported numbers. That's the denominator problem, as he put it.

What he is saying is that doing a death rate estimate using only actual numbers will overestimate the fatality rate. You can't simply say - The worldwide toll as of 2:30 am on March 6 is 98,436 confirmed cases and 3,387 deaths therefore the fatality rate is 3.4%. That would greatly overestimate the death rate because many infected people will never be positively tested for COVID19 even though they had it.


Yeah they have been stating as much for a few weeks now, that is the "denominator problem" I'll wait more before I panic. It is definitely serious, but I think they will have much better data in a few weeks.
IrishTxAggie
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MouthBQ98
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If they died before they could heal, they would show damage.

What stuns me, and yet not that much, is all the selfish complete ass holes that go about spreading this stuff recreationally
MouthBQ98
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I also think it's a bit alarming how people are so cavalier about this only killing "old people".
IrishTxAggie
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You know, because shipping and manufacturing has been brought to a grinding halt
Signel
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UncoverAg00 said:

My oldest has severe asthma... requiring biological injections to control it. My fear is she may be one of the ouliers. The age argument helps, but doesn't completely put me at ease. Make sense? This is a respitory illness and thus is very real for my family... I do my best to not panic, but until it's proven my girls' condition isn't something I need to fuss over regarding this virus, I'm going to worry.
Same here! My daughter has to do zolair shots bi-weekly, and the monthly round of allergy shots. We almost lost her to swine flu. We were in the hospital for 2 weeks when that one hit. There is a reason I have a pile of N95 masks, and I am very concerned.
bmks270
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MouthBQ98 said:

If they died before they could heal, they would show damage.

What stuns me, and yet not that much, is all the selfish complete ass holes that go about spreading this stuff recreationally


People with flu - stay in bed, rest.

People with corona virus - travel the world, visit ski resorts, attend concerts, go on cruises.
Signel
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Stat Monitor Repairman said:

Definitely something off about how all this is playing out.
HIMSS was just canceled yesterday. It is a huge Healthcare conference. Many of the large corporations like IBM and Amazon backed out earlier this week. Furthermore, the leadership said they were concerned many of the attendees were going to be needed back home to help patients.
AgsMyDude
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Rapier108 said:

AgsMyDude said:

LostInLA07 said:

Premium said:

So two of the ones in Houston are supposedly at Memorial Hermann in The Woodlands.


Source? Personal knowledge?


I saw information about this on reddit. Something like 10 people in Houston were all part of that tour group to Egypt
And everyone from the group is quarantined and being tested.


How long have they been under quarantine? They've been back for weeks.

The Rice student has now come up positive was on campus for a couple of days before quarantine.


https://emergency.rice.edu/news/rice-alert-coronavirus-alert
Proposition Joe
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Yeah I often wonder how isolated these people's lives are... Like, I'm really not that concerned what will happen to me if I manage to get the virus - my fear is that i don't want to be around my 70 year old parents if they are at a high risk.
cisgenderedAggie
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The "mutation" paper is now receiving calls for retraction.

http://virological.org/t/response-to-on-the-origin-and-continuing-evolution-of-sars-cov-2/418

Some excerpts:

Quote:


It is, however, important to appreciate that finding a majority of samples with a particular mutation is not evidence that viruses with that mutation transmit more readily. To make this claim would, at very minimum, require a comparison to be made to expectations under a null distribution assuming equal transmission rates. As this has not been performed by the authors, we believe there is insufficient evidence to make this suggestion, and that it is incorrect (and irresponsible) to state that there is any difference in transmission rates. Differences in the observed numbers of samples with and without this mutation are far more likely to be due to stochastic epidemiological effects.
-snip-
Evidence from the widespread media uptake (35 articles at last count), and many comments on social media in response to this article, suggests that the unsupported claims made by Tang et al. have already spread undue fear.



Quote:


When interpreting their results, Tang et al. do not consider that sequencing error could be a driver of a relative excess of singleton nonsynonymous mutations. This possibility is important because sequencing errors will be at low frequency as they are rare and cannot be transmitted, but real mutations observed mutations can be at any frequency because they can be transmitted. Additionally, purifying selection can only act on real mutations, and not sequencing errors. Therefore it is very possible that sequencing error will have a higher nonsynonymous to synonymous ratio, and these mutations will be at low frequency, which will mimic the action of purifying selection suppressing the frequency of nonsynonymous mutations.



Quote:

Given these flaws, we believe that Tang et al. should retract their paper, as the claims made in it are clearly unfounded and risk spreading dangerous misinformation at a crucial time in the outbreak



Lots of other jargon, but mostly saying that the results are largely a result of small sample size, creation of definitions that are self-reinforcing, overinterpretation of functional result of such changes.
B-1 83
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KorbinDallas said:



Unbelievable...
Yes it is. I'm checking my CBP source on that one......
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