Some of these hurt me on a personal level either because they are considered the signature song, or because they are not recognized as awesome, or both. Examples:
REM -- Everybody Hurts - correct, not their greatest, but sig song is "The One I Love"
Joy Division - Love Will Tear Us Apart -- I can't. One of the greatest club dance tunes ever.
The Smiths -- How Soon Is Now? -- Sig song is "There is a Light That Never Goes Out"; and both are awesome
The Pixies -- Where is My Mind" -- I say "Here Come's Your Man" is sig, but Where Is is awesome
Depeche Mode -- Personal Jesus -- Not a sig, even for that album -- Enjoy the Silence. Not terrible either. Sig? Too Many others to name, but maybe Everything Counts. All awesome
GNR - Paradise City, way less sig than Sweet Child and Welcome to the Jungle. But agree, don't like that one.
Queen - Bohemian Rhapsody. Uh, We Will Rock You says hi.
Bill Withers -- Lean on Me. What? How can you not like that song?
The Cure -- Friday I'm in Love. One of my least favorite Cure songs but not their sig. Boys Don't Cry.
New Contributions:
Alanis Morissette -- Ironic
Beach Boys -- California Girls; David Lee Roth -- same