This stuff has taken over my back yard. I put down Amaze in March and it still came up. I sprayed 2-4 D from the premixed hose attachment bottle last week and it killed some other weeds, but he Gripe weed Is totally unphased. Any recommendations to kill it?

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In the lawn: If you have St. Augustine, centipede or zoysia, spot treat with Atrazine during the summer.

It is too hot to apply over the entire lawn, but you can spray spots or patches of the chamberbitter weeds where they occur. Make two applications following label directions. Atrazine also serves as a preemergence herbicide, so the areas where you have treated twice should not see much regrowth (do not use Atrazine in beds).

For best control, spray the lawn with Atrazine in early to mid-May before it gets so hot. Then, spot treat during the summer if needed. Isoxaben (see above) could be applied to the lawn in early summer as a preemergence herbicide to prevent seeds of this weed from sprouting and growing.

Also, mow your lawn at the highest recommended height to make it more competitive St. Augustine at 3 inches, centipede and zoysia at 2 inches.

A bad chamberbitter infestation in a lawn may indicate a lawn that is in poor vigor. Chamberbitters have a harder time establishing in a thick, healthy, vigorous lawn. Make sure you provide your lawn with proper care (mowing, watering, fertilizing, sun) to minimize chamberbitter problems.

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http://www.lsuagcenter.com/portals/blogs/southerngarden/chamberbitter-weeds

Is this still the best way to treat this stuff? I stayed on schedule this year with fall/winter/spring fertilizer and fall/spring pre-emergent and I sprayed 2-4D in May, but this stuff started popping up in June when it was already too hot to spray 2-4D. The little area I tried lost some St. Augustine even though I applied it early in the morning before the temp was over 90. I've never seen it before, but it started showing up in my beds and then sod last year and this year it's gotten even worse. I hand pull a lot of it, but there's thousands of these sprigs everywhere. My lawn is the healthiest it's ever been and a mix of St. Augustine and Zoysia. Located in Longview for Latitude reference.