Been on these fake pouches but off the good stuff for around 3 years now. Northerner.com sells them cheaper than the gas stations. I buy 25 pack at a time.
SAHE is serious adverse health effectsQuote:
The only SAHE from NRT exposure we identified was an increase in respiratory congenital abnormalities reported in one study. Limited evidence indicated a lack of effect between NRT exposure and SAHEs for CVD and various reproduction/developmental endpoints. For cancer, stroke and other SAHEs, the evidence was inadequate to demonstrate any association with NRT use. Our conclusions agree with recent statements from authoritative bodies.
https://www.ahajournals.org/doi/full/10.1161/01.cir.94.5.878Quote:
Background Insulin sensitivity and cardiovascular risk profile were examined in 20 healthy, nonobese, middle-aged men who were long-term users of nicotine-containing chewing gum and in 20 matched control subjects who did not use nicotine.
Methods and Results Long-term use of nicotine-containing chewing gum was associated with insulin resistance and hyperinsulinemia. The degree of insulin sensitivity correlated negatively to the extent of nicotine use measured as plasma cotinine levels.
Conclusions These findings suggest that nicotine is the major constituent in cigarette smoke that leads to insulin resistance, metabolic abnormalities associated with the insulin resistance syndrome, and increased cardiovascular morbidity. Thus, the use of nicotine replacement therapy during smoking cessation should be transient and limited.
I'm not injecting nicotine into my bloodstream. There may be some dermal ingestion via gum, but most of it is swallowed. This research suggests that gum may be safer than a nicotine pouch which is mostly dermal absorption.Quote:
At present, it is not possible to draw a conclusion whether nicotine itself may act as a complete carcinogen. In mice studies with NNK as an initiator, nicotine acts as a promoter after injection or dermal absorption, but not after oral administration. In drinking water experiments, there is considerable first-pass metabolism of nicotine before nicotine enters the systemic circulation. As a result, serum concentration is much lower after ingestion than after i.p. administration. Nicotine enhanced tumor growth and progression after injection of malignant cells in mice. Enhancements were found both after exposure of nicotine by i.p. injection, oral, and skin administration. Moreover, cotinine did also enhance tumor growth.
Depending on the brand they come in 1.5, 2, 3, 4, 6, 8 mg per pouch.BurnetAggie99 said:
There's like 20 pouches in a can. I usually do 2 at a time. Each pouch is 6mg of nicotine.
nealan said:
Black Buffalo is a decent alternative. They have with and without nicotine. One downside is that you have to order it online