LinkQuote:
Texas has run out of its supply of monoclonal antibodies, and infusion centers in the state will be unable to offer the treatment until more shipments are sent out in January.
Infusion centers in Austin, El Paso, Fort Worth, San Antonio and The Woodlands have all gone through their supply of sotrovimab, the only antibody treatment believed to be effective against the omicron variant, the Texas Health and Human Services Commission said on Monday.
The agency said infusion centers in Texas will be unable to offer the treatment until "federal authorities ship additional courses of sotrovimab to Texas in January."
Texas out of monoclonal antibodies?
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73 Replies |
Last: 4 yr ago by MisterShipWreck
All because Joe is unnecessarily rationing them and shipping them to blue states.
Clown show, clown shoes….however you want to call it.
...take it easy on me, I'm a normal horn
He's had how long to ramp up production and distribution? Feds should just get out of the way.
Well, New York City has 25% of all Covid cases as of last week so most of the treatments should probably be sent to a blue state right now.HowdyTAMU said:
All because Joe is unnecessarily rationing them and shipping them to blue states.
TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
FJB
I read somewhere Biden has stopped shipping the antibodies because they we not sure if they were effective against Omicron.
You may not be a moron, but some people think you are.
TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
This is true, it is just a cold for 99% of people. Unfortunately the government and media fear porn has everyone worried it's Ebola, so people run out and get whatever treatment they can right away, regardless of how sick they actually are.
Not aware of a single poster who thinks the elderly and obese/diabetic etc. are not at risk. Nice try.TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
Some people are forced to test to be able to merely work or travel. But having a test option could be a serious problem for them, whether they want to test or not.
For those at risk (i.e., the fat and old), the treatment is a wonderful therapy.TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
For the rest of us, the shanghai sniffles have been a non-starter since the beginning.
You sound like you want to injure the elderly? Is that true?
There we're plenty of posts this week from people who saw nothing wrong with going out shopping, to family Christmas, etc when ill.SB 43rd STREET OG said:Not aware of a single poster who thinks the elderly and obese/diabetic etc. are not at risk. Nice try.TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
The monoclonal antibodies are largely ineffective against Omicron. They are running into the same issues the vaccines are.
https://www.tandfonline.com/doi/full/10.1080/22221751.2021.2023330
https://www.tandfonline.com/doi/full/10.1080/22221751.2021.2023330
Quote:
Consistently, of the eight approved or authorized antibodies, all but sotrovimab has lost their neutralizing activity against the Omicron pseudovirus [8]. Sotrovimab binds to a cryptic RBD epitope [9] that seems to be less affected in Omicron, thus its neutralizing potency against Omicron only dropped by 3-fold [8]. Similarly, neutralizing efficacy of convalescent sera were reduced against Omicron psedovirus by 8.4-folds on average [10].
Quote:
Recent results, however, indicate that Omicron significantly escapes two-doses' vaccines, ranging from complete loss to 33- to 44-fold reduction of neutralizing activities [8, 12] Sera from people who received the third dose of vaccines maintained about 10% of the neutralizing activity, and such neutralizing activity was completely lost after 3 months [12].
These findings may temper the prospect of controlling spread of Omicron and the future SARS-CoV-2 variants by vaccination, especially if the virus continues to enhance its abilities in immune evasion and transmissibility. On Dec 20, 2021, the CDC estimated that Omicron may have 1.6-fold increased transmissibility compared to Delta
Quote:
Omicron has revealed to us that SARS-CoV-2 has the potential go beyond the protective threshold provided by vaccines and antibodies. Playing catchup to SARS-CoV-2 selects for more resistant and transmissible variants and may not be successful in the long run. Besides updating vaccines against Omicron or its future derivatives, we need to speed up the development of novel antivirals.
So, which therapeutic properties are most impactful against COVID19? A recent modelling study has pointed out that while reducing COVID19 severity, mortality, or preventing hospitalization are all beneficial, reducing duration of infectiousness would provide three-times the beneficial impact of any of the other properties [18].
A future COVID19 therapy should ideally meet three criteria: 1.) it should have high potency and resistance barrier; 2.) it should be effective at reducing viral replication and minimize viral spreading; 3.) it should be effective against all SARS-CoV-2 variants, including the future ones, and avoid introducing additional selective pressure towards resistant variants.
There is nothing wrong with going out in public. I am unvaccinated, have had Covid, and do not wear masks.
Should I wear a star to so indicate?
Should I wear a star to so indicate?
End Of Message said:For those at risk (i.e., the fat and old), the treatment is a wonderful therapy.TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
For the rest of us, the shanghai sniffles have been a non-starter since the beginning.
You sound like you want to injure the elderly? Is that true?
Don't you understand the mindset of liberals?
Not sure where you got that. I said "if true this is not good" and you came to "want to injure the elderly" lol. Fantastic reasoning!End Of Message said:For those at risk (i.e., the fat and old), the treatment is a wonderful therapy.TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
For the rest of us, the shanghai sniffles have been a non-starter since the beginning.
You sound like you want to injure the elderly? Is that true?
Missed those last two words in my post.End Of Message said:
There is nothing wrong with going out in public. I am unvaccinated, have had Covid, and do not wear masks.
Should I wear a star to so indicate?
No clue what you are talking about. I think the vast majority of humans think if you have cold or flu you should not knowingly try to infect others.TXAGFAN said:There we're plenty of posts this week from people who saw nothing wrong with going out shopping, to family Christmas, etc when ill.SB 43rd STREET OG said:Not aware of a single poster who thinks the elderly and obese/diabetic etc. are not at risk. Nice try.TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
They told me that was the case at my doc appointment today.
TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
Sounds like you strawmanned your way into choosing "our" narrative for us.
TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
Just so we have you on the record, is Omicron a cold or Airborne Ebola Super AIDS?
Remember when they said the state governors should get out of the way?LostInLA07 said:
He's had how long to ramp up production and distribution? Feds should just get out of the way.
Obtuse and actually quite misinformed. Congrats!TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
Now please explain how for a vast majority of people it is just the sniffles but there are those vulnerable that this is a miracle treatment at the behest of their doctor.
Stop trying to look through a straw and open your ****ing eyes!
He knows at least 50 people who have died from omicron already.Maroon Dawn said:TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
Just so we have you on the record, is Omicron a cold or Airborne Ebola Super AIDS?
You must be new here. This is just the one I commented on, there was another thread or two with similar sentiments about just carrying on as normal even when sick.SB 43rd STREET OG said:No clue what you are talking about. I think the vast majority of humans think if you have cold or flu you should not knowingly try to infect others.TXAGFAN said:There we're plenty of posts this week from people who saw nothing wrong with going out shopping, to family Christmas, etc when ill.SB 43rd STREET OG said:Not aware of a single poster who thinks the elderly and obese/diabetic etc. are not at risk. Nice try.TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
https://texags.com/forums/16/topics/3261697/
My 78 year old mother in law was turned down in The Woodlands after her doctor ordered it for her last week. Was told they were saving the doses.
How do they know which variant you have? Does that come back on all PCR tests?
How do they know which variant you have? Does that come back on all PCR tests?
The only antibody treatment which is still effective against Omicron is the one made by GlaxoSmithKline as it targets part of the virus which doesn't mutate. The ones by Regeneron and Eli Lilly don't have much effect because the part they targeted mutated with Omicron.
The US didn't purchase much of the GSK product, although Florida bought some on their own after Biden cut off their supplies of the one made by Regeneron.
The US didn't purchase much of the GSK product, although Florida bought some on their own after Biden cut off their supplies of the one made by Regeneron.
It requires specific lab test to determine which variant. None of the tests just to see if you have it will tell you the variant.Darth Randy said:
My 78 year old mother in law was turned down in The Woodlands after her doctor ordered it for her last week. Was told they were saving the doses.
How do they know which variant you have? Does that come back on all PCR tests?
That was my recollection of what happened in Florida as well. Wonder what Abbott will do?Rapier108 said:
The only antibody treatment which is still effective against Omicron is the one made by GlaxoSmithKline as it targets part of the virus which doesn't mutate. The ones by Regeneron and Eli Lilly don't have much effect because the part they targeted mutated with Omicron.
The US didn't purchase much of the GSK product, although Florida bought some on their own after Biden cut off their supplies of the one made by Regeneron.
That's what I thought. I have no idea why she was told no other than they were saving it. And also she was told her symptoms were not severe enough apparently.
But was then told to go to Walgreens (while positive, mind you, *gasp*) to get some OTC cold and flu meds.
I'm so sick of this ****ing virus. Nothing makes any ****ing sense.
But was then told to go to Walgreens (while positive, mind you, *gasp*) to get some OTC cold and flu meds.
I'm so sick of this ****ing virus. Nothing makes any ****ing sense.
Exactly what we should've done from the onset. Protect the vulnerable but the rest continue to live and participate in life.TXAGFAN said:You must be new here. This is just the one I commented on, there was another thread or two with similar sentiments about just carrying on as normal even when sick.SB 43rd STREET OG said:No clue what you are talking about. I think the vast majority of humans think if you have cold or flu you should not knowingly try to infect others.TXAGFAN said:There we're plenty of posts this week from people who saw nothing wrong with going out shopping, to family Christmas, etc when ill.SB 43rd STREET OG said:Not aware of a single poster who thinks the elderly and obese/diabetic etc. are not at risk. Nice try.TXAGFAN said:
What's the concern? It's just a cold and perfectly safe to go about normal business and interactions according to many on F16.
If true this is not good, but you guys need to pick a narrative.
https://texags.com/forums/16/topics/3261697/
This is what FJB means when he said "its up to the states to solve it". He's going to withhold treatments and funding unless the states become the bad guys and implement the democrats fascist plans.
Its the way tyrants work, and 81,000,000, including tens of thousands of aggies wanted this and actively promote it on this website.
Its the way tyrants work, and 81,000,000, including tens of thousands of aggies wanted this and actively promote it on this website.
My guess is there probably is some benefit, but just not enough to justify giving it to everyone who tests positive. They're likely saving what is left for people who would fall into the extremely high risk category.Darth Randy said:
That's what I thought. I have no idea why she was told no other than they were saving it. And also she was told her symptoms were not severe enough apparently.
But was then told to go to Walgreens (while positive, mind you, *gasp*) to get some OTC cold and flu meds.
I'm so sick of this ****ing virus. Nothing makes any ****ing sense.
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