Fully vaxxed 5x less likely to get covid.

3,598 Views | 19 Replies | Last: 3 yr ago by BlackGoldAg2011
PJYoung
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8:01a, 9/11/21
AG
Brand new large study released:

Overall, fully vaccinated people are about five times less likely to become infected with delta, 10 times less likely to be hospitalized with COVID-19 from delta, and 11 times less likely to die from the variant, according to the studies.

https://arstechnica.com/science/2021/09/unvaccinated-are-5x-more-likely-to-catch-delta-11x-more-likely-to-die/


That assessment was based on the largest U.S. study to date of the real-world effectiveness of all three vaccines, involving about 32,000 patients seen in hospitals, emergency departments and urgent care clinics across nine states from June through early August.
While the three vaccines were collectively 86% effective in preventing hospitalization, protection was significantly higher among Moderna vaccine recipients (95%) than among those who got Pfizer-BioNTech (80%) or Johnson & Johnson (60%). That finding echoes a smaller study by the Mayo Clinic Health System in August, not yet peer-reviewed, which also showed the Moderna vaccine with higher effectiveness than Pfizer-BioNTech at preventing infections during the delta wave.

https://www.washingtonpost.com/health/2021/09/10/moderna-most-effective-covid-vaccine-studies/

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KidDoc
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8:56a, 9/11/21
AG
Whoop team Moderna!
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
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bay fan
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In reply to KidDoc • 9:36a, 9/11/21
S
Feeling like the luck of the draw did me well with Moderna too!
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bay fan
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In reply to PJYoung • 9:40a, 9/11/21
S
Wonder if this will slow down the "you're just as likely to get it from someone who is vaccinated" comments and people will begin to connect the dots to fewer contagious vaccinated people in the general population.
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03_Aggie
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In reply to bay fan • 10:06a, 9/11/21
bay fan said:
Wonder if this will slow down the "you're just as likely to get it from someone who is vaccinated" comments and people will begin to connect the dots to fewer contagious vaccinated people in the general population.


Not much considering it dropped from 11 to 4.6. And the time period studied for delta was less than a month. Doesn't do much to dispel the rumor.

Quote:
In terms of infections, fully vaccinated people were about 11 times less likely to get an infection in the pre-delta period, compared with the unvaccinated (with a 95 percent confidence interval of 7.8 to 15.8). That ratio dropped to 4.6 less likely in the post-delta period (with a 95 percent confidence interval of 2.5 to 8.5).
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NicosMachine
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8:56p, 9/11/21
AG
You should see how well people who've had Covid are doing. Natural immunity is the bomb.
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Ol_Ag_02
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11:00p, 9/11/21
AG
We should really stop calling this a vaccine. I realize the CDC recently changed the definition of a vaccine on their website, but for the love. . . .
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The Big12Ag
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In reply to NicosMachine • 10:20a, 9/12/21
NicosMachine said:
You should see how well people who've had Covid are doing. Natural immunity is the bomb.
I find this post a bit oddly worded. If you had Covid before the vaccine was available, or before you were able to get scheduled for the vaccine, I hope the illness wasn't too bad and am glad it has provided you natural immunity - and I hope that immunity is strong and long lasting! But this is worded in a way that suggests one might choose contracting Covid rather than choosing a vaccine in order to boost your immune system, I personally don't think thats a wise choice even though I do agree natural immunity is great - it's what our bodies are designed to do - and is at least comparable to any vaccine triggered immune response. Everyone who had it and survived it with no lasted effects, which IS the vast majority, that is great. But again, I could ask people who've had Covid to see how well they are doing - but like four and a half million wouldn't be able to respond to the question. I think the vaccine is the best choice if still in a position to make that choice.
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GeographyAg
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In reply to NicosMachine • 10:39a, 9/12/21
AG
NicosMachine said:
You should see how well people who've had Covid are doing. Natural immunity is the bomb.


Yeah, it's hit or miss. I have a friend in her thirties, skinny and healthy, who had it back in January and now has it again. She's not the only one I know who has had it twice (not to mention the "long Covid" cases) she's just the latest.
If I’m posting, it’s actually Mrs GeographyAg.
Mr. GeographyAg is a dedicated lurker.
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fightingfarmer09
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In reply to The Big12Ag • 12:20p, 9/12/21
Getting the J&J shot and then getting Covid was the best thing that could happen to me.

Single shot vaccine. And a mild version of delta.

I'll take that as the end of Covid in our house.
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Teslag
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In reply to bay fan • 12:29p, 9/12/21
AG
bay fan said:
Wonder if this will slow down the "you're just as likely to get it from someone who is vaccinated" comments and people will begin to connect the dots to fewer contagious vaccinated people in the general population.


I don't think anyone here has made the claim that "you're just as likely" rather that you're still likely to get it from the vaccinated. Which according to this study is undeniably true.

I got moderna. I'm glad I did. And I didn't get it to stop the spread or protect others. I got it to keep my ass out of the hospital in the rare event I needed to go if I got covid. That's the mindset we all need so we take pressure off hospitals. But we need to drop the illusions that the vaccine will eradicate or even stop the spread of covid.
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In reply to GeographyAg • 1:03p, 9/12/21
Player To Be Named Later
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3:19p, 9/12/21
AG
But yet we still can't get full approval for the Moderna vaccine? How much longer are they going to take on that?
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GeographyAg
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In reply to [removed post] • 3:42p, 9/12/21
AG
SoupNazi2001 said:
GeographyAg said:
NicosMachine said:
You should see how well people who've had Covid are doing. Natural immunity is the bomb.


Yeah, it's hit or miss. I have a friend in her thirties, skinny and healthy, who had it back in January and now has it again. She's not the only one I know who has had it twice (not to mention the "long Covid" cases) she's just the latest.


Just having it twice means nothing. Is it mild?
She's sicker than the first time. First time was mostly a bad headache and some mild cold symptoms. This time she's been very achy and feverish and a lot more miserable. That's what her husband has reported, anyway. He used the words "I'm more worried about her" and he's the one who had the antibody infusion.
If I’m posting, it’s actually Mrs GeographyAg.
Mr. GeographyAg is a dedicated lurker.
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KidDoc
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In reply to Player To Be Named Later • 4:56p, 9/12/21
AG
Player To Be Named Later said:
But yet we still can't get full approval for the Moderna vaccine? How much longer are they going to take on that?


My understanding is that the FDA wanted larger studies and to look at different doses primarily due to the myocarditis reports in young patients. The original Pfizer EUA was only 1000 teens and didn't find the myocarditis risk until more patients were vaccinated. They don't want to authorize prematurely which I greatly appreciate.

I suspect with time it will end up being two half doses or even a single dose for young patients.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
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Player To Be Named Later
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In reply to KidDoc • 5:02p, 9/12/21
AG
I hear a lot about the myocarditis in people potentially occurring in people who have received Moderna more so than Pfizer. These are both mRNA vaccines correct? How would the course of action be any different in the two, or is it just dosage issue?
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htxag09
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In reply to Teslag • 6:06p, 9/12/21
AG
Salute The Marines said:
bay fan said:
Wonder if this will slow down the "you're just as likely to get it from someone who is vaccinated" comments and people will begin to connect the dots to fewer contagious vaccinated people in the general population.


I don't think anyone here has made the claim that "you're just as likely" rather that you're still likely to get it from the vaccinated. Which according to this study is undeniably true.

I got moderna. I'm glad I did. And I didn't get it to stop the spread or protect others. I got it to keep my ass out of the hospital in the rare event I needed to go if I got covid. That's the mindset we all need so we take pressure off hospitals. But we need to drop the illusions that the vaccine will eradicate or even stop the spread of covid.

There are several people on here saying you're just as likely to get it, that it doesn't help prevent the spread at all. Hell, some are saying your more likely to get it and spread it.
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KidDoc
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In reply to Player To Be Named Later • 6:07p, 9/12/21
AG
Player To Be Named Later said:
I hear a lot about the myocarditis in people potentially occurring in people who have received Moderna more so than Pfizer. These are both mRNA vaccines correct? How would the course of action be any different in the two, or is it just dosage issue?


The current theory is dosing. It is the same theory as to why moderna is so far more effective in adults. Dose titration over time depending on age and immune status will be critical long term to maximize effectiveness vs side effects in my opinion.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
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KidDoc
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6:09p, 9/12/21
AG
Dose comparison and Pfizer rationale for lower dose on roll out.

https://news.yahoo.com/pfizer-picked-covid-19-vaccine-125332549.html
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94chem
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6:58p, 9/12/21
Anecdotally, my wife had J&J and got a headache for a day when our 11 year old brought it home from Pine Covid. My breakthrough case with Pfizer was apparently an hour nap one afternoon. Both vaccines did their job. But yeah, J&J wasn't quite as strong. Either way, winning.
94chem,
That, sir, was the greatest post in the history of TexAgs. I salute you. -- Dough
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BlackGoldAg2011
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9:37a, 9/13/21
AG
While I always appreciate new additional information, I do wish these studies would break their "unvaccinated" group into "unvaccinated-recovered" and "unvaccinated-nave". Not doing that paints a partially incorrect picture as we track vaccine effectiveness over time. If we believe that recovering from COVID provides some level of immunity then it would make sense that as a larger and larger group of the population gets COVID the difference in likelihood of getting covid between vaxxed and unvaxxed would get smaller. Because a larger and larger portion of the unvaxxed group actually has antibodies. This would make the vaccine appear to be losing effectiveness over time even if it were not moving at all.

now, there were not enough covid infections in the time between the pre-delta and active delta study periods to move the needle as much as it did, but for instance during delta, if you just look at the two groups, you get a roughly 78% efficacy of the vaccine. If you assume 35% of the "unvaccinated" group had recovered from covid and actually had immunity equal to being vaccinated, that boosts the calculated vaccine efficacy to 85% because there was actually much larger spread in the covid naive group that the initial numbers would imply. using the same method and assumptions, the pre-delta period would have put vaccine efficacy at 94% (vs 91% not counting covid recovered immunity). Now these are basic numbers that get further confounded when acknowledging that some of the vaccinated are also covid recovered and likely have "super immunity" so trying to guess at exactly how it all untangles gets super messy. But also, if these studies would simply attempt to break out each group into covid-naive, and covid-recovered, the data would really be much more meaningful in absolute metrics, rather then simply being limited to relativistic conclusions.
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