Vaccination-Associated Myocarditis in Children Ages 12-17

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samurai_science
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10:49p, 9/8/21
The rate of hospitalization for a cardiac adverse events was 2 to 6 times HIGHER than if the child had contracted COVID-19

https://www.medrxiv.org/content/10.1101/2021.08.30.21262866v1.full.pdf
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samurai_science
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10:52p, 9/8/21
https://www.bbc.com/news/health-57496074

Covid: Children aged 12-17 unlikely to be offered vaccine in UK
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lobopride
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4:24a, 9/9/21
I see no reason for my children to be vaccinated. I am vaccinated but I just don't see the upside for them.
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fightingfarmer09
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6:02a, 9/9/21
This is the myopreicarditis data on children from the CDC. Literally posted less than a month ago. This is not just another vaccine for kids. It's actually pretty dangerous in comparison to other vaccines.


https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2021-08-30/03-COVID-Su-508.pdf

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AggieHusker
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10:21a, 9/9/21
AG
This study contradicts the OP's article and finds the exact opposite. Cases of myocarditis are higher from the virus than from the vaccine.

https://www.medrxiv.org/content/10.1101/2021.07.23.21260998v1

This is not peer reviewed either, so take that for what it's worth.

Quote:
Conclusions Myocarditis (or pericarditis or myopericarditis) from primary COVID19 infection occurred at a rate as high as 450 per million in young males. Young males infected with the virus are up 6 times more likely to develop myocarditis as those who have received the vaccine.
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TXTransplant
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In reply to AggieHusker • 10:34a, 9/9/21
AggieHusker said:
https://www.medrxiv.org/content/10.1101/2021.07.23.21260998v1

This is not peer reviewed either, so take that for what it's worth.

Quote:
Conclusions Myocarditis (or pericarditis or myopericarditis) from primary COVID19 infection occurred at a rate as high as 450 per million in young males. Young males infected with the virus are up 6 times more likely to develop myocarditis as those who have received the vaccine.


I just want to point out that the sample set used to draw all the conclusions in that paper was 276. The CDC slides only reported on about 1300 data points.

And from that they extrapolated the rate of CAEs into the larger population.

I'm not saying these observations are not cause for concern and further study, but the sample sets are VERY small. And it's know that this age group cohort is much less likely to get vaccinated - and the ones who are getting the vaccine are more likely to have (or think they have) pre-exiting conditions that make them "high-risk".

So, in addition to being very small, the data set is not randomized or controlled and is skewed to a specific cohort.

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AggieHusker
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In reply to TXTransplant • 10:38a, 9/9/21
AG
Just to clarify, the article I posted was not using VAERS data, it used health records from the TriNetX Research Network, aggregating electronic health records from 48 mostly large U.S. Healthcare Organizations (HCOs).

The 276 you mention is from the OP's article.
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TXTransplant
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In reply to AggieHusker • 10:44a, 9/9/21
AggieHusker said:
Just to clarify, the article I posted was not using VAERS data, it used health records from the TriNetX Research Network, aggregating electronic health records from 48 mostly large U.S. Healthcare Organizations (HCOs).

The 276 you mention is from the OP's article.


You are correct. My mistake - two very similar-looking articles with similar links. Looks like the data set for the article you posted was about 14,000.

They did conclude that the results suggest the risk of myocarditis from Covid infection itself exceeds the risk from vaccination "by a considerable margin" for 12-19 year old males and females.
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AggieHusker
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In reply to TXTransplant • 10:54a, 9/9/21
AG
No worries, my original post wasn't very clear. I've edited to make it more clear that what I posted contradicts the OP's article.

The OP's article doesn't even compare apples to apples. They're comparing their calculated myocarditis risk to the hospitalization risk. What they need to compare is the risk of myocarditis from the virus compared to the risk of myocarditis from the vaccine.
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TXTransplant
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In reply to AggieHusker • 10:59a, 9/9/21
AggieHusker said:
No worries, my original post wasn't very clear. I've edited to make it more clear that what I posted contradicts the OP's article.

The OP's article doesn't even compare apples to apples. They're comparing their calculated myocarditis risk to the hospitalization risk. What they need to compare is the risk of myocarditis from the virus compared to the risk of myocarditis from the vaccine.


Good point. And to clarify, the study you posted included 14000 data points on kids who have had Covid-19 (not 14000 vaccinated kids). They looked at the rate of myocarditis in kids who were diagnosed with Covid and compared that to data reporting of myocarditis in vaccinated kids.
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gunan01
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In reply to fightingfarmer09 • 11:22a, 9/9/21
AG
Your conclusion is not compatible with what the data represents. The sample sizes are tiny in those CDC slides.
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TXTransplant
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11:31a, 9/9/21
If you believe the data in the study posted on the OP, the rate of CAEs in vaccinated boys aged 12-17 ranges between 94-162 per million. That's out of a sample set of 276

According to the article posted by AggieHusker, the rate of myocarditis in boys aged 12-17 who have had a Covid infection is about 450 per million. That's out of a sample set of 14000

Also, the study in the OP estimated the rate of hospitalization for kids who contract Covid and have no comorbidities (including obesity and asthma) to be 44.4 per million. The rate for kids with at least one comorbidity who get Covid is 210.5 million.

That's a 4.7 fold increase in risk of hospitalization if a kid gets Covid and has comorbidities. THAT'S what everyone should be talking about!
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TXTransplant
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11:39a, 9/9/21
But even the hospitalization data in the article in the OP is skewed.

If I understood that study correctly, they authors just estimated the rate of comorbidities to be 33%, which is in line with what's "observed" among the general population. They got the raw data on pediatric Covid hospitalizations and applied this assumption to it.

The reality is, probably way more than 33% of pediatric Covid hospitalizations have comorbidities. Because we know the virus disproportionately affects people with pre-existing conditions more severely.
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AggieHusker
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12:55p, 9/9/21
AG
MIS-C appears to be a bigger risk than myocarditis from Covid.

https://covid.cdc.gov/covid-data-tracker/#mis-national-surveillance
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PJYoung
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2:52p, 9/9/21
AG
OP continues to post misleading (at best) links.
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Diggity
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8:59a, 9/10/21
AG


Samarai change his name? wonder why?
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aggiemike02
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In reply to Diggity • 9:02a, 9/10/21
AG
so fing weird
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gunan01
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In reply to PJYoung • 9:14a, 9/10/21
AG
PJYoung said:
OP continues to post misleading (at best) links.
He's a known Forum 16 troll. I always wonder what the end game is for those guys to post these kinds of misleading narratives. Do they want people to be sick because of MAH FREEDOMS?
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WolfCall
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4:18p, 9/12/21
WolfCall
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4:18p, 9/12/21
AG
I have a few citations for recent journal articles I obtained from a PubMed (National Library of Medicine) search using the following search terms phrase: Covid Vaccine AND Heart.

Some of you may be confronted with the decision about whether or not to vaccinate your children......

Citations follow with title of journal article in bold text and abbreviated journal name italicized.
Quote:
Quote:
Items 1-29 of 29 (Display the 29 citations in PubMed)

1: Sivakumaran P, Sunny J, Tsagkridi A, Khanji MY. Myopericarditis following SARS-CoV-2 mRNA vaccine: the role of cardiac biomarkers and multimodality imaging. Eur Heart J Cardiovasc Imaging. 2021 Sep 6:jeab183. doi: 10.1093/ehjci/jeab183. Epub ahead of print. PMID: 34487161.

2: McFadyen JD, Peter K. The known knowns and known unknowns of vaccine-induced thrombotic thrombocytopaenia. Cardiovasc Res. 2021 Sep 2:cvab275. doi: 10.1093/cvr/cvab275. Epub ahead of print. PMID: 34472568.

3: Tate C, Demashkieh L, Hakmeh W. Isolated Tachycardia Presenting After Pfizer- BioNTech COVID-19 Vaccination. Cureus. 2021 Jul 28;13(7):e16706. doi: 10.7759/cureus.16706. PMID: 34466331; PMCID: PMC8397831.

4: Lee E, Chew NWS, Ng P, Yeo TJ. Reply to "Letter to the editor: Myocarditis should be considered in those with a troponin rise and unobstructed coronary arteries following PfizerBioNTech COVID-19 vaccination". QJM. 2021 Aug 31:hcab232. doi: 10.1093/qjmed/hcab232. Epub ahead of print. PMID: 34463770.

5: Ford GA, Hargroves D, Lowe D, Hicks N, Lip GYH, Rooney G, Oatley H. Targeted atrial fibrillation (AF) detection in COVID-19 vaccination clinics. Eur Heart J Qual Care Clin Outcomes. 2021 Aug 27:qcab061. doi: 10.1093/ehjqcco/qcab061. Epub ahead of print. PMID: 34448836.

6: Shazley O, Alshazley M. A COVID-Positive 52-Year-Old Man Presented With Venous Thromboembolism and Disseminated Intravascular Coagulation Following Johnson & Johnson Vaccination: A Case-Study. Cureus. 2021 Jul 14;13(7):e16383. doi: 10.7759/cureus.16383. PMID: 34408937; PMCID: PMC8362796.

7: Li C, Chen Y, Zhao Y, Lung DC, Ye Z, Song W, Liu FF, Cai JP, Wong WM, Yip CC, Chan JF, To KK, Sridhar S, Hung IF, Chu H, Kok KH, Jin DY, Zhang AJ, Yuen KY. Intravenous injection of COVID-19 mRNA vaccine can induce acute myopericarditis in mouse model. Clin Infect Dis. 2021 Aug 18:ciab707. doi: 10.1093/cid/ciab707. Epub ahead of print. PMID: 34406358.

8: Kim IC, Kim H, Lee HJ, Kim JY, Kim JY. Cardiac Imaging of Acute Myocarditis Following COVID-19 mRNA Vaccination. J Korean Med Sci. 2021 Aug 16;36(32):e229. doi: 10.3346/jkms.2021.36.e229. PMID: 34402228; PMCID: PMC8369314.

9: King WW, Petersen MR, Matar RM, Budweg JB, Cuervo Pardo L, Petersen JW. Myocarditis following mRNA vaccination against SARS-CoV-2, a case series. Am Heart J Plus. 2021 Aug;8:100042. doi: 10.1016/j.ahjo.2021.100042. Epub 2021 Aug 9. PMID: 34396358; PMCID: PMC8349733.

10: Jain SS, Steele JM, Fonseca B, Huang S, Shah S, Maskatia SA, Buddhe S, Misra N, Ramachandran P, Gaur L, Eshtehardi P, Anwar S, Kaushik N, Han F, Chaudhuri NR, Grosse-Wortmann L. COVID-19 Vaccination-Associated Myocarditis in Adolescents. Pediatrics. 2021 Aug 13:e2021053427. doi: 10.1542/peds.2021-053427. Epub ahead of print. PMID: 34389692.

11: Sung JG, Sobieszczyk PS, Bhatt DL. Acute Myocardial Infarction Within 24 Hours After COVID-19 Vaccination. Am J Cardiol. 2021 Oct 1;156:129-131. doi: 10.1016/j.amjcard.2021.06.047. Epub 2021 Jul 12. PMID: 34364657; PMCID: PMC8272970.

12: Park JY, Kim JH, Lee IJ, Kim HI, Park S, Hwang YI, Jang SH, Jung KS. COVID-19 vaccine-related interstitial lung disease: a case study. Thorax. 2021 Aug 6:thoraxjnl-2021-217609. doi: 10.1136/thoraxjnl-2021-217609. Epub ahead of print. PMID: 34362838.

13: Das BB, Moskowitz WB, Taylor MB, Palmer A. Myocarditis and Pericarditis Following mRNA COVID-19 Vaccination: What Do We Know So Far? Children (Basel). 2021 Jul 18;8(7):607. doi: 10.3390/children8070607. PMID: 34356586; PMCID: PMC8305058.

14: Fanni D, Saba L, Demontis R, Gerosa C, Chighine A, Nioi M, Suri JS, Ravarino A, Cau F, Barcellona D, Botta MC, Porcu M, Scano A, Coghe F, Orr G, Van Eyken P, Gibo Y, La Nasa G, D'aloja E, Marongiu F, Faa G. Vaccine-induced severe thrombotic thrombocytopenia following COVID-19 vaccination: a report of an autoptic case and review of the literature. Eur Rev Med Pharmacol Sci. 2021 Aug;25(15):5063-5069. doi: 10.26355/eurrev_202108_26464. PMID: 34355379.

15: Andraska EA, Kulkarni R, Chaudhary M, Sachdev U. Three cases of acute venous thromboembolism in females following vaccination for COVID-19. J Vasc Surg Venous Lymphat Disord. 2021 Aug 2:S2213-333X(21)00392-9. doi: 10.1016/j.jvsv.2021.07.009. Epub ahead of print. PMID: 34352418; PMCID: PMC8327605.

16: Pepe S, Gregory AT, Denniss AR. Myocarditis, Pericarditis and Cardiomyopathy After COVID-19 Vaccination. Heart Lung Circ. 2021 Oct;30(10):1425-1429. doi: 10.1016/j.hlc.2021.07.011. Epub 2021 Jul 31. PMID: 34340927; PMCID: PMC8324414.

17: Das BB, Kohli U, Ramachandran P, Nguyen HH, Greil G, Hussain T, Tandon A, Kane C, Avula S, Duru C, Hede S, Sharma K, Chowdhury D, Patel S, Mercer C, Chaudhuri NR, Patel B, Khan D, Ang JY, Asmar B, Sanchez J, Bobosky KA, Cochran CD, Gebara BM, Gonzalez Rangel IE, Krasan G, Siddiqui O, Waqas M, El-Wiher N, Freij BJ. Myopericarditis following mRNA COVID-19 Vaccination in Adolescents 12 through 18 Years of Age. J Pediatr. 2021 Jul 30:S0022-3476(21)00736-8. doi: 10.1016/j.jpeds.2021.07.044. Epub ahead of print. PMID: 34339728; PMCID: PMC8321962.

18: Sokolska JM, Kurcz J, Kosmala W. Every rose has its thorns - acute myocarditis following COVID-19 vaccination. Kardiol Pol. 2021 Jul 31. doi: 10.33963/KP.a2021.0075. Epub ahead of print. PMID: 34331307.

19: Boscolo Berto M, Spano G, Wagner B, Bernhard B, Hner J, Huber AT, Grni C. Takotsubo Cardiomyopathy After mRNA COVID-19 Vaccination. Heart Lung Circ. 2021 Jul 15:S1443-9506(21)01133-1. doi: 10.1016/j.hlc.2021.06.521. Epub ahead of print. PMID: 34330629; PMCID: PMC8279960.

20: Tano E, San Martin S, Girgis S, Martinez-Fernandez Y, Sanchez Vegas C. Perimyocarditis in Adolescents After Pfizer-BioNTech COVID-19 Vaccine. J Pediatric Infect Dis Soc. 2021 Jul 28:piab060. doi: 10.1093/jpids/piab060. Epub ahead of print. PMID: 34319393; PMCID: PMC8344528.

21: Williams CB, Choi JI, Hosseini F, Roberts J, Ramanathan K, Ong K. Acute Myocarditis Following mRNA-1273 SARS-CoV-2 Vaccination. CJC Open. 2021 Jul 14. doi: 10.1016/j.cjco.2021.07.008. Epub ahead of print. PMID: 34308326; PMCID: PMC8278869.

22: Bozkurt B, Kamat I, Hotez PJ. Myocarditis With COVID-19 mRNA Vaccines. Circulation. 2021 Aug 10;144(6):471-484. doi: 10.1161/CIRCULATIONAHA.121.056135. Epub 2021 Jul 20. PMID: 34281357; PMCID: PMC8340726.

23: Singh B, Kaur P, Cedeno L, Brahimi T, Patel P, Virk H, Shamoon F, Bikkina M. COVID-19 mRNA Vaccine and Myocarditis. Eur J Case Rep Intern Med. 2021 Jun 14;8(7):002681. doi: 10.12890/2021_002681. PMID: 34268277; PMCID: PMC8276934.

24: Shaw KE, Cavalcante JL, Han BK, Gössl M. Possible Association Between COVID-19 Vaccine and Myocarditis: Clinical and CMR Findings. JACC Cardiovasc Imaging. 2021 Sep;14(9):1856-1861. doi: 10.1016/j.jcmg.2021.06.002. Epub 2021 Jun 16. PMID: 34246586; PMCID: PMC8245050.

25: Al-Ahmad M, Al-Rasheed M, Shalaby NAB. Acquired thrombotic thrombocytopenic purpura with possible association with AstraZeneca-Oxford COVID-19 vaccine. EJHaem. 2021 May 18:10.1002/jha2.219. doi: 10.1002/jha2.219. Epub ahead of print. PMID: 34226899; PMCID: PMC8242544.

26: Deb A, Abdelmalek J, Iwuji K, Nugent K. Acute Myocardial Injury Following COVID-19 Vaccination: A Case Report and Review of Current Evidence from Vaccine Adverse Events Reporting System Database. J Prim Care Community Health. 2021 Jan-Dec;12:21501327211029230. doi: 10.1177/21501327211029230. PMID: 34219532; PMCID: PMC8255555.

27: Lee E, Chew NW, Ng P, Yeo TJ. A spectrum of cardiac manifestations post Pfizer-BioNTech COVID-19 vaccination. QJM. 2021 Jun 30:hcab177. doi: 10.1093/qjmed/hcab177. Epub ahead of print. PMID: 34191024.

28: Habib MB, Hamamyh T, Elyas A, Altermanini M, Elhassan M. Acute myocarditis following administration of BNT162b2 vaccine. IDCases. 2021 Jun 16;25:e01197. doi: 10.1016/j.idcr.2021.e01197. PMID: 34189042; PMCID: PMC8220234.

29: Kim HW, Jenista ER, Wendell DC, Azevedo CF, Campbell MJ, Darty SN, Parker MA, Kim RJ. Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination. JAMA Cardiol. 2021 Jun 29:e212828. doi: 10.1001/jamacardio.2021.2828. Epub ahead of print. PMID: 34185046; PMCID: PMC8243258.
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Zobel
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In reply to WolfCall • 4:53p, 9/12/21
AG
Quit spamming this search vomit everywhere please.
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spherical
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In reply to samurai_science • 11:41p, 9/13/21
AG
https://sciencebasedmedicine.org/dumpster-diving-in-vaers-doctors-fall-into-the-same-trap-as-antivaxxers/
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AggieHusker
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In reply to spherical • 8:28a, 9/14/21
AG
Fantastic article. Thanks for posting.
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