Monoclonal Antibodies - IV or Injection?

2,162 Views | 9 Replies | Last: 3 yr ago by TexAg2001
TexAg2001
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AG
I took a PCR COVID test yesterday and am waiting on the results. I decided to take an at-home rapid test this morning and it came back positive. I have a fever (101 degrees), body aches, loss of smell, very minor cough, and pretty much no other symptoms. The fever is easily reduced using OTC drugs but comes back every 4-5 hours. My symptoms started Saturday evening. I'm vaccinated (J&J)

I've been looking into getting the monoclonal antibodies and have been on hold with Houston Methodist waiting for a virtual appointment. I've been waiting for an hour and their system shows I have at least another 2 hours to wait. In the meantime, I found a place called "Breathe MD" that offers it via IV infusion or injection. The injection is less expensive ($125) and I can make an appointment tomorrow morning. The IV is $175 and soonest available appointment is in 3 days.

Is there a difference between receiving it via IV or Injection? Is one delivery method more effective than the other?
TexAg2001
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AG
A 6/4/21 press release on Regeneron's website states: "As part of the updated EUA, REGEN-COV should be administered by intravenous (IV) infusion; subcutaneous (SC) injections are an alternative when IV infusion is not feasible and would lead to a delay in treatment."

So, it sounds like IV infusion is preferred, but injection is just OK?
Duncan Idaho
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Not a doctor but I'd probably lean towards time to treatment over delivery of treatment.

Basically the first available
Ribbed Paultz
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Also not a doctor but I think that SC is only an option if they can't get an IV in the person for some reason.
TexAg2001
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AG
My PCR test came back positive late yesterday. Fortunately, I was able to get into Houston Methodist this afternoon to get the Monolonal Antibodies IV infusion. Their setup was very efficient and they were treating ALOT of people. There were at least 30-40 other people in the same room as me, which was essentially a large meeting room with dividers between chairs. The infusion took about 30 minutes and then had to wait an hour before being released.

My symptoms have been pretty mild so far. A 101 degree fever every 4-5 hours (easily controlled by meds), body aches (this is the worst symptom so far), loss of smell and taste, minor cough, headache. They took vitals 4 times during and after the infusion and my oxygen levels were between 98-100 each time.
Texas Aggies 12
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TexAg2001 said:

My PCR test came back positive late yesterday. Fortunately, I was able to get into Houston Methodist this afternoon to get the Monolonal Antibodies IV infusion. Their setup was very efficient and they were treating ALOT of people. There were at least 30-40 other people in the same room as me, which was essentially a large meeting room with dividers between chairs. The infusion took about 30 minutes and then had to wait an hour before being released.

My symptoms have been pretty mild so far. A 101 degree fever every 4-5 hours (easily controlled by meds), body aches (this is the worst symptom so far), loss of smell and taste, minor cough, headache. They took vitals 4 times during and after the infusion and my oxygen levels were between 98-100 each time.

How many days after initial symptoms did you have this infusion? How many days can you wait until after first symptoms these infusions aren't effective?

Guy on a Buffalo
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AG
1). Go to Pushhealth.com

2). Get ivermectin

3). ?????

4). Profit

-----------------------
Truth without love is brutality. Love without truth is compromise.
TexAg2001
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AG
My symptoms started Saturday night and I got the infusion on Tuesday afternoon, so about 3 days. From what I've read and been told, the infusion is only effective if you get it done within 10 days of symptom onset, and it's much more effective the sooner you get it done.

After the infusion yesterday, my fever spiked to around 101.3 and stayed there until falling asleep for the night, even after taking Tylenol. I was a little worried and it was weird because I didn't feel "feverish". However, I ended up sleeping through the night for the first time since Friday and woke up this morning fever free and my other symptoms seem to have gotten better. Body aches are significantly less, no headache, still a slight cough.

Things seem to be improving so I remain cautiously optomistic.
Texas Aggies 12
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Good to hear.

So you had the tele conference with Methodist got your PCR test and then they scheduled you for the antibodies infusion.

Did you have a choice on locations to have this done or they just booked you where first available?
GuatemalanAg
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AG
Glad to hear you are doing better
TexAg2001
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AG
My timeline of events:
  • Saturday, 8/28: 101 degree fever started around 8pm
  • Sunday, 8/29: Took PCR Test at CVS, fever persisted, lost sense of smell, body started aching
  • Monday, 8/30: Took rapid at home test (positive), previous symptoms became worse, taste started becoming "muted", but not lost. Began taking additional supplements (zinc, vitamins). Set up virtual appointment with Houston Methodist. After 3 hours on hold I spoke with a nurse practitioner (NP) about 7pm. While on hold I received the positive results from the PCR test. I asked for, and the NP prescribed, Albuterol, plus a prescription cough suppressant, Benzonatate. The NP asked that I email my positive PCR test results to them and she gave my info to their referral service to schedule the infusion. They would not schedule it without a positive test in their files.
  • Tuesday, 8/31: Symptoms much worse than day before. 8am - I hadn't heard from Methodist so I tried to schedule infusion with Breathe MD, but soonest available was Friday, 9/3. I sent them an email asking if they could squeeze me in sooner. 10:30am - got call from Houston Methodist, who then scheduled the infusion for 1pm same day. While receiving infusion at Methodist, Breathe MD replied to my email saying they could squeeze me in for that day, which means I would have had another option if Methodist didn't come through like they did.
  • Today: Feeling great. Nearly all symptoms are gone. Fever gone, aches mostly gone, no headache, extremely minor cough, no issues breathing. I still can't smell anything, but I feel like 90%. It seriously feels like a miracle.

I did the infusion at The Medical Center. TMC happens to be close to me, but I was willing to drive to anywhere to make sure I got it done sooner rather than later. I should add that I think Houston Methodist will only do the infusion if you have at least 1 risk factor. I'm relatively healthy and don't have any pre-existing conditions, but qualified due to my BMI.
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