Do we know for sure that the vaccines won't cause issues later in life?

19,858 Views | 189 Replies | Last: 3 yr ago by Trucker 96
bay fan
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S
Windy City Ag said:

Quote:

I posted my opinion on a message board. Like it or not, that's what TexAgs is...a place for opinions. I chose not to read all 5 pages, and instead, post my opinion. If it triggered you, go change your mask, yell at the clouds, and kindly go away. Nothing any of the doctors here have to say will change my mind, because I'm doing what I feel is right for me.
You probably did not read the big post at the top titled "Please read before posting" . . . . this board was specifically designed to not be "a place for opinions". This forum was designed to filter out gut feelings and politically motivated screeds and allow posters direct access to qualified medical opinions.

Hence in that post, from the moderators


Quote:

To be clear: This is not a place to post your opinion as fact or to post information not rooted in clear facts. This is not a place to have political arguments or to detail your opinions about how well or poorly the government is handling the issue. This is not a place to rant about media conspiracies. This is not a place to critique other people for their level of concern or efforts to prepare. There are forums for (some of) those conversations, but they don't belong here.

Again, our goal is to highlight some of the helpful information from doctors, public health experts, and others that is already appearing in other forums and to give our community a specific place to ask questions and get helpful, accurate answers.
So don't take it so personally when you viewpoints are taken very seriously here. It was designed for educated medical professionals and those looking to ask them questions rather than argue all night long.
Sadly that rule seems terribly diluted now.
Infection_Ag11
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AG
TXTransplant said:

Infection_Ag11 said:

I disagree with much of what has been implemented in many states and at the national level since last May or so. And the mask debate is effectively a moot point because far too small a percentage of the public wears them correctly to actually assess efficacy.

For example, the claim that we don't know whether the vaccines decrease asymptomatic transmission is just not true. We know from international studies, most notably those in Israel and South Korea, that it dramatically decreases such transmission. And unless we assume this virus behaves distinctly differently from essentially every other RNA virus we've ever discovered, we already knew that would be the case.

Probably my biggest gripe overall has been this sort of intentionally obtuse mindset from many in the scientific community whereby we grant this virus magical powers that make it wholly unique among RNA respiratory viruses. There's just never been any evidence at any point along the way that the response to natural infection or vaccine would be unpredictable or different than to other similar viruses.


This right here is what's made me want to pull my hair out, especially the last few months since the vaccine was released.

I'm not a doctor, but I am an engineer with working knowledge of microbiology and biochemistry.

As an engineer, I live and die, not by the "science" but by the DATA - specifically the trends in the data (and NOT the outliers).

I understand doctors who treat individual patients being hesitant to use aggregate data. However, doctors and disease specialists who work in public policy have an obligation to look and the data and interpret it in a way that best benefits society as a whole.

I'm so disappointed and frustrated by the extreme narrative that's been pushed under the guise of "if it saves just one life..."

I definitely can see the light at the end of the tunnel with this virus, but I am afraid that the medical community and various government officials have set a very bad precedent for how we handle future situations similar to this.

And after that ridiculous press conference yesterday, I have lost all faith in the CDC. Prior to this, I often gave deference/the benefit of the doubt to doctors and researchers. I have a PhD, so I know what it takes to become an objective expert in your field. Sadly, over the last year, I have begun to question the motives of many people we call "experts" and "professionals".


Assuming we continue reigning this pandemic in, the biggest longterm consequence of COVID19 may end up being the irreparable harm done to the perception of and trust in medical science. Some of the things done/said have given the conspiracy theorists and those with a baseline distrust of modern medicine/general authority all the ammo they'll ever need.

I've always dealt with vaccine hesitancy/anti-vaccine stuff, but it's gone to a whole different level now. The suspicion so many patients have towards anything I try to do for them is getting really hard to overcome.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
TXTransplant
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I hear you. As an engineer/scientist/researcher, I can't get over the outright lies that are being spread.

And this has also opened my eyes to the garbage/fear porn that gets spewed on other topics - specifically the safety of the food we eat and certain consumer products (ie, "clean beauty").

I always knew that subculture was out there, but I just kind of ignored it. Now, I'm just disgusted and am trying to actively support people who are dedicated to refuting this nonsense.
tysker
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AG
Infection_Ag11 said:

TXTransplant said:

Infection_Ag11 said:

I disagree with much of what has been implemented in many states and at the national level since last May or so. And the mask debate is effectively a moot point because far too small a percentage of the public wears them correctly to actually assess efficacy.

For example, the claim that we don't know whether the vaccines decrease asymptomatic transmission is just not true. We know from international studies, most notably those in Israel and South Korea, that it dramatically decreases such transmission. And unless we assume this virus behaves distinctly differently from essentially every other RNA virus we've ever discovered, we already knew that would be the case.

Probably my biggest gripe overall has been this sort of intentionally obtuse mindset from many in the scientific community whereby we grant this virus magical powers that make it wholly unique among RNA respiratory viruses. There's just never been any evidence at any point along the way that the response to natural infection or vaccine would be unpredictable or different than to other similar viruses.


This right here is what's made me want to pull my hair out, especially the last few months since the vaccine was released.

I'm not a doctor, but I am an engineer with working knowledge of microbiology and biochemistry.

As an engineer, I live and die, not by the "science" but by the DATA - specifically the trends in the data (and NOT the outliers).

I understand doctors who treat individual patients being hesitant to use aggregate data. However, doctors and disease specialists who work in public policy have an obligation to look and the data and interpret it in a way that best benefits society as a whole.

I'm so disappointed and frustrated by the extreme narrative that's been pushed under the guise of "if it saves just one life..."

I definitely can see the light at the end of the tunnel with this virus, but I am afraid that the medical community and various government officials have set a very bad precedent for how we handle future situations similar to this.

And after that ridiculous press conference yesterday, I have lost all faith in the CDC. Prior to this, I often gave deference/the benefit of the doubt to doctors and researchers. I have a PhD, so I know what it takes to become an objective expert in your field. Sadly, over the last year, I have begun to question the motives of many people we call "experts" and "professionals".


Assuming we continue reigning this pandemic in, the biggest longterm consequence of COVID19 may end up being the irreparable harm done to the perception of and trust in medical science. Some of the things done/said have given the conspiracy theorists and those with a baseline distrust of modern medicine/general authority all the ammo they'll ever need.

I've always dealt with vaccine hesitancy/anti-vaccine stuff, but it's gone to a whole different level now. The suspicion so many patients have towards anything I try to do for them is getting really hard to overcome.
Historically doctors have a higher trust rating than most other professions but I think the public has been more skeptical of the larger industrial medical complex for years now especially given such a large recent increases in insurance premiums. And that skepticism is just filtering down more often. People trust their doctors but often not the larger industry.

And I think there is research saying the public that interacts with medical professionals more often has a higher satisfaction and higher opinion of doctors than than that dont often see medical professionals which may a self-serving opinion both ways. But as more of the pubic cannot afford to see doctors, specialist, receive treatments, medications etc., one wonders how this will this will affect public perception of medical professionals over time.
FratboyLegend
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Irwin M. Fletcher said:

aTm2004 said:

mrmill3218 said:

Just a thought experiment:

How do we know the covid vaccines are safe long term? Do we know that there won't be and side effects or health issues months or years from now? I know they are emergency use approved by the FDA, but they're not officially FDA approved from what I understand.
We do not know, which is why I am not going to get one. If I was 65, it would be a different story. I'd be in a much higher risk group, and if something happened 10 years down the road, what difference would it really make since I had lived majority of my life? Much different for someone in their 30s.

Certainly your choice but do we know the long term effects of COVID itself. Or do we know the patients in their 30's that have had a major decrease in lung function will this ever resolve? I'm just using your logic for not getting it to saying the same can be said the other way around.
As I have said many times regarding vaccination: there is a single risk equation, and it has two unknowns.
#CertifiedSIP
Windy City Ag
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AG
Quote:

As I have said many times regarding vaccination: there is a single risk equation, and it has two unknowns.
Agreed . . a good framework. From my perspective, the estimation of the two unknowns is all over the place on a personal level.

I have known three people that died of the disease and four long haulers with symptoms ranging from the annoying and benign (phantosmia - she smells a cigarette smoke odor all day long five months after her recovery) to the frightening (a 40 year old triathelete that has had persistent blood clot and inflammation issues that impact his ability to walk 7 full months after his recovery). I am probably seeing that and overestimating my personal risk.

I also see people ignore a lot of the vetting and analysis and history of these new vaccine concepts and anchor on some general undefined negative outcome could still be out there maybe. I personally think they are overestimating risk.

So I weighed these two and went and got the vaccine. I am sure others feel differently.
FarversFight
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jpb1999 said:

I admit I skipped pages 2 and 3 of this thread, so forgive me if already covered, but (1) are you saying this mRNA type vaccine has been used before in other vaccines? If so, which ones and how long ago? (2) So is it not true that previous animal testing (on other mRNA type of vaccines) caused deaths in the animals that were re-exposed to the virus they were vaccinated for? (3) What about people with differing types of auto-immune disorders. Is there a risk there to trigger auto-immune reponses or are there still unknowns there?


I am just going to bump these questions as I had them myself - mainly 1 and 2. Thanks
Windy City Ag
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AG
This AP Fact check talked about this and interviewed an MRNA researcher name Drew Weissman. He was the co-author of a paper that supposedly got people concerned on this subject.

https://apnews.com/article/fact-checking-afs:Content:9889529642

Quote:

In an email, Morrow provided the AP with an article referring to a 2018 journal review on mRNA vaccines co-authored by Dr. Drew Weissman, who has studied mRNA for decades and participated in groundbreaking research on the molecule. Morrow noted that in the 2018 article on "mRNA vaccines a new era in vaccinology," a number of possible adverse effects for mRNA vaccines were listed, including concerns about autoimmunity.

Weissman said such concerns weren't applicable with the COVID-19 vaccines because they use a new kind RNA, which would not cause autoimmune disease.

Modified mRNA vaccines have since been given to people for five years now.

"There is no data that says an mRNA vaccine can cause an autoimmune disease," he said in an email. "I have not seen or heard of a single report that mRNA vaccines cause autoimmunity."

Another good red on your questions.

https://www.medpagetoday.com/infectiousdisease/covid19/89998

Quote:

While an mRNA vaccine has never been on the market anywhere in the world, mRNA vaccines have been tested in humans before, for at least four infectious diseases: rabies, influenza, cytomegalovirus, and Zika.

In 2017, German biotech CureVac published results in The Lancet for a phase I trial of its mRNA rabies vaccine, and in January of this year the company issued results via press release from a phase I trial of its low-dose rabies mRNA vaccine.

Last year, Moderna and German researchers published the phase I results of two mRNA vaccines against influenza. In January, Moderna announced results of its phase I study of an mRNA vaccine against cytomegalovirus, and just this past April as the pandemic raged, the company reported interim data from its mRNA vaccine against Zika.



FratboyLegend
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Windy City Ag said:

So I weighed these two and went and got the vaccine. I am sure others feel differently.
To each his own prerogative. Agreed.
#CertifiedSIP
chimpanzee
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Infection_Ag11 said:

TXTransplant said:

Infection_Ag11 said:

I disagree with much of what has been implemented in many states and at the national level since last May or so. And the mask debate is effectively a moot point because far too small a percentage of the public wears them correctly to actually assess efficacy.

For example, the claim that we don't know whether the vaccines decrease asymptomatic transmission is just not true. We know from international studies, most notably those in Israel and South Korea, that it dramatically decreases such transmission. And unless we assume this virus behaves distinctly differently from essentially every other RNA virus we've ever discovered, we already knew that would be the case.

Probably my biggest gripe overall has been this sort of intentionally obtuse mindset from many in the scientific community whereby we grant this virus magical powers that make it wholly unique among RNA respiratory viruses. There's just never been any evidence at any point along the way that the response to natural infection or vaccine would be unpredictable or different than to other similar viruses.


This right here is what's made me want to pull my hair out, especially the last few months since the vaccine was released.

I'm not a doctor, but I am an engineer with working knowledge of microbiology and biochemistry.

As an engineer, I live and die, not by the "science" but by the DATA - specifically the trends in the data (and NOT the outliers).

I understand doctors who treat individual patients being hesitant to use aggregate data. However, doctors and disease specialists who work in public policy have an obligation to look and the data and interpret it in a way that best benefits society as a whole.

I'm so disappointed and frustrated by the extreme narrative that's been pushed under the guise of "if it saves just one life..."

I definitely can see the light at the end of the tunnel with this virus, but I am afraid that the medical community and various government officials have set a very bad precedent for how we handle future situations similar to this.

And after that ridiculous press conference yesterday, I have lost all faith in the CDC. Prior to this, I often gave deference/the benefit of the doubt to doctors and researchers. I have a PhD, so I know what it takes to become an objective expert in your field. Sadly, over the last year, I have begun to question the motives of many people we call "experts" and "professionals".


Assuming we continue reigning this pandemic in, the biggest longterm consequence of COVID19 may end up being the irreparable harm done to the perception of and trust in medical science. Some of the things done/said have given the conspiracy theorists and those with a baseline distrust of modern medicine/general authority all the ammo they'll ever need.

I've always dealt with vaccine hesitancy/anti-vaccine stuff, but it's gone to a whole different level now. The suspicion so many patients have towards anything I try to do for them is getting really hard to overcome.
Appreciate your input, and I have many family members that are deeply suspicious of physicians following numerous encounters that reinforced the notion. Notably, when you're confidently told something is definitely true only for it to have been false, you feel like you're on your own.

There are many bad faith arguments against the current vaccines, but without arguing against those straw men, what would be the best argument in favor of the safety of these vaccines? Best I could gather is that they are not materially different mechanistically than many other very common vaccines with long safety records, but I don't know that for a fact myself.

Thanks.
jpb1999
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AG
Quote:

jpb1999 said:
I admit I skipped pages 2 and 3 of this thread, so forgive me if already covered, but (1) are you saying this mRNA type vaccine has been used before in other vaccines? If so, which ones and how long ago? (2) So is it not true that previous animal testing (on other mRNA type of vaccines) caused deaths in the animals that were re-exposed to the virus they were vaccinated for? (3) What about people with differing types of auto-immune disorders. Is there a risk there to trigger auto-immune reponses or are there still unknowns there?


I am just going to bump these questions as I had them myself - mainly 1 and 2. Thanks

When you get a chance, can you answer these questions if known? Much appreciated!

_________________________________________

Spane Bohem


hbc07
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AG
coolerguy12 said:

KidDoc said:

COVID-19 and Blood Type | Harvard Medical School


Does the statement below mean an O patient who has CV19 is less likely to show positive on a CV19 test, or an O patient is less likely to have CV19?

Quote:

An intriguing finding from the study was that there appeared to be a greater chance of people with blood types B and AB who were Rh positive testing positive for the virus. Even stronger evidence was assembled by the team that symptomatic people with blood type O were less likely to test positive.


I'm assuming that by clarifying "symptomatic people" that is assuming they have CV19 but the test is a false negative.

Would this hold true for antibody tests as well?
Did anyone ever answer this?
jpb1999
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AG
So nothing on my questions or the above questions?
_________________________________________

Spane Bohem


Guppy91
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AG
jpb1999 said:

I admit I skipped pages 2 and 3 of this thread, so forgive me if already covered, but (1) are you saying this mRNA type vaccine has been used before in other vaccines? If so, which ones and how long ago? (2) So is it not true that previous animal testing (on other mRNA type of vaccines) caused deaths in the animals that were re-exposed to the virus they were vaccinated for? (3) What about people with differing types of auto-immune disorders. Is there a risk there to trigger auto-immune reponses or are there still unknowns there?

Complete side question regarding UC/Crohns - Some meds like Stelara target certain proteins (IL-12 and IL-23) that may cause the inflamation. Could a mRNA vaccine be developed to target these inflammation proteins to treat UC/Crohns? Or is that what the autoimmune disease already does, that those proteins trigger the auto-immune response causing the inflammation?
Bump
bigtruckguy3500
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Another good video on vaccine development in general and in context of the COVID19 vaccine:

Trucker 96
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