I've got a 40 year old red oak with some limbs hanging really low. I trimmed about half (one side of the tree) of the low hanging limbs in February but still have another half to trim. Should I wait until winter or trim now? It's currently loaded with acorns. I'm also wondering if I could trim a few 2-3" diameter limbs for right now and do the rest in winter. Overall, wondering how much risk is there in trimming the tree now.

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Read up on Oak Wilt. They recommend not pruning Feb-June to avoid the risk of it. I'd do it now before it cools off.