Always seems to be some cardiologist hate on here. Maybe sometimes justified, but often exaggerated I think. But obviously I am biased. I typically steer clear of these discussions on message boards because I think most people already have their minds made up, and nothing I say will do much to change anything. Just some food for thought and then I'll hand it back over to the internet.
TLDR:
-Cardiovascular disease is complex and I caution against over simplifying it on either side.
Longer version:
-Everyone agrees that cardiovascular disease is a complex equation with many factors - some modifiable, some not. It is true that LDL is not the holy grail. But it's also incorrect to think that it doesn't matter at all. Saying LDL doesn't matter is the same over-simplification that many are upset at doctors for doing when they only look at their LDL and no other markers. The truth is always in the middle.
-Diet matters. Always has, always will. Whether you take statins or not.
-Statins are also not the holy grail. But the data is pretty clear that they help - particularly in the right patient population. The statin hate always confuses me, and is second only to anything related to COVID.
-There are so many factors that it's almost impossible to compare apples to apples. A lot of people post about their LDL and weight and calcium score and this and that. But it all has to be taken into context (age, risk factors, family history, etc.). Simply comparing lipid numbers and calcium scores or weights isn't equal.
-And finally I looked up the Ornish diet and the publication referenced about reversal of CAD because I wasn't familiar with this info. I'm not arguing for or against the diet, but a few take-home points just to consider:
--The study has 35 patients total
--Over 5 years, the % stenosis of lesions on cath reduced from 40% to 37% on the diet. The % stenosis in the control arm went from 41% to 51%. Of course, I'd much rather be in the reduction arm, but at this rate, with no dietary changes it would take roughly 15-20 years until the lesions became significant or obstructive. The average age was 62.
--Within the control arm, the patients that took statins, the % stenosis went from 46% to 51%. Patients that weren't on statins went from 41% to 60%.
---My summary would be that this is a small underpowered study, but is promising. I wish it would be validated on a larger scale, but of course there's no money in that so no one will pay for that study. Although I personally doubt the diet "reverses" CAD, it is feasible that it slows progression, which is about the best we have at this point. And even in this small study that I don't think is great, there is more evidence that statin use slows CAD progression.
OK board, fire away.