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Home administration of ketamine

1,646 Views | 16 Replies | Last: 4 days ago by Max Power
General Jack D. Ripper
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I'm seeing this stuff advertised on Reddit for home use. I understand ketamine has potential benefits for depression, but home administration seems primed for abuse.

Does anyone know someone that used this home therapy? Is the amount provided insignificant enough to minimize abuse?

Doctors, what do you think?
But I know no matter what the waitress brings
I shall drink it and always be full, yeah I will drink it and always be full
bigtruckguy3500
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Sounds like fun. I know there are oral and nasal spray formulations of ketamine that can be prescribed. There probably is potential for abuse, but much harder than the IV formulation. I would hope no one is getting IV ketamine for home use.
Max Power
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AG
I just completed about 6 weeks of treatment with Mindbloom, which is one of the companies you can do this with. I started looking into it last year and found there's basically 3 different options for Ketamine. You can go to a clinic and receive it through an IV which costs $1k+ for a single session and not covered by insurance, you can go through a different kind of clinic where you get it administered via nasal spray which can be covered by insurance, or you can take it at home which isn't covered. I chose the third option in that I could do it at home and it wasn't cost prohibitive for the treatment I went through.

I've been suffering from depression for a long time, but anxiety only over the past few years. Here's the breakdown of my full experience. I've never taken any psychadelic drugs in my life just for reference.

I met with a doctor via a zoom session where you discuss how you're feeling and go through your medical history and then they make the decision as to whether or not to proceed. They approved me and sent me the medication. They do have to go through all your current medication to confirm you're not on anything that it can interact with which was mainly benzodiazepines. Before your first session you meet with a counselor to guide you through the process. The medication comes in the form of tablets that melt in your mouth, but you don't swallow it, you let it sit in there for 7:00 and then spit out what's left. Then you put on a face mask and listen to music through their app. The session takes about an hour from start to finish. The first session was really emotional for me, it helped me remember some really important things in my life, some very specific moments with my wife and my daughter and they were very vivid and just kept playing in my head. After the first session you meet with the counselor and doctor again to see about adjusting the medicine which we increased mine a bit.

The second session helped me figure out a big cause of anxiety is that I've associated very specific negative experiences soon after positive experiences. In my head it's like I'm always waiting for the other shoe to drop, especially if something good happens. I know that one doesn't cause the other, but in my mind it's happened so many times that negative follows positive. My anxiety really kicked off several years ago when I found out one of my friends died the same day as I got a promotion at work. But going back through my own personal history there's a lot of instances like that happening, it's difficult for me to accept positive experiences for what they are without worrying about the negative.

The third experience was also emotional. It was the most psychadelic experience I've had to date and part of it involved my dog. She died last year and it's been rough on everyone in our house, worst on me. During the trip I was on I could feel her laying next to me on the bed, I could feel her fur, her body along my right side which is where she would lay next to me on the couch. It was like someone you lost came to visit, it was an emotional roller coaster.

The fourth experience helped me to realize I need to get outside more. I've been working from home for a long time at a stressful job and I think it's made me tie my home and work together too much in my mind. I need a separation of those things. I'm changing jobs in about a month where I'll be getting out of the house and doing some travel from time to time which I'm looking forward to.

The last couple of times haven't been very intense but I haven't gone into them with anything specific in mind. Going into your session with an intent does matter in my experience.

I actually have my final consultation today to go over my experience. I haven't decided if I want to continue it or not but I would say it's been a positive experience as it helped me dig through my mind for positive things. I did not have a bad trip on any of them. The main thing on the negative side I realized is I don't have a lot of enjoyable experiences in my life to draw from whether that was childhood, college, or young adult life which reinforced those feelings of depression going back a long way. It wasn't cheap, but I think it was worth the cost. I never found myself feeling like I needed the drug again so it didn't feel addictive to me. You can't drive the rest of the day if you take that medicine but I tried to always take it toward the end of the day. You can't eat for at least 3 hours before so the medicine is the most effective.
I went into this to use the medication as a tool, and that's what it did. I can see how others would abuse this medication but I came in with a purpose and that's what it served.

Sorry if I overshared but I wanted to lay the whole thing out in the event it helps you.
rjhtamu
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AG
Ketamine therapy and psychedelics as well show promise. However, we still don't know how long therapy should last for the best benefits. 3 weeks, 6 weeks? 9 months? That isn't known.

The strongest benefit is also with guided therapy and counseling sessions.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
GeorgiAg
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AG
Still thinking about this.

Comedian Ron White discussed his trip to Cost Rica (?) or somewhere similar to a resort where he did psychedlic therapy and it helped him quit drinking. It was a good listen.
rjhtamu
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AG
Interestingly enough, yet another benefit to semaglutide (Ozempic) seems to be in addiction management.
People on these drugs also seem to have less cravings for cigarettes, alcohol, and other addictive substances.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
OasisMan
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AG
If you don't mind me asking,
What was the ~approx cost
Max Power
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AG
It doesn't bother me at all, it was between $1200-$1300 overall which included 6 sessions of medication as well as the doctor visits and counselor meetings. I actually was able to stretch that to 7 sessions of medication since I was able to take a bit less than directed for the last 3 sessions.

There are some other options online I see as well. There's one called betterucare which looks to be cheaper than Mindbloom. There's another company called Joyous that is for microdosing and it's $129/month and you take it daily.

Mindbloom is pretty pricey to me, but I got good results so I won't complain. If it was cheaper I'd just keep going but due to the cost I'm going to see how long how I'm feeling right now lasts. You can do a lot of research on your options online, including a lot of information on Reddit.
GeorgiAg
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AG
You said it lasts for about an hour. Is there any kind of hangover or residual effects?
AggieLAX
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AG
Have you looked into creatine supplementation?
rjhtamu
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AG
Some ER's are also considering ketamine infusions for acutely depressed and suicidal patients.

The typical process is to screen them in the ER and then hold them potentially for days while they wait for an inpatient psychiatric bed somewhere. There are not nearly enough beds for those needing them.

However, a ketamine infusion in the ER seems to curb the depression symptoms, lower their imminent risk for suicide drastically, allow discharge to home with ongoing outpatient therapy, and seems to have some long-lasting effects.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Max Power
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AG
GeorgiAg said:

You said it lasts for about an hour. Is there any kind of hangover or residual effects?
You feel a little woozy and light headed afterward, but nothing crazy. It's best to take it at night so you can go to bed a little later. You're not supposed to drive or do anything significant for the rest of the day. Some people take anti-nausea medication for it but I never felt it was needed. There's no residual side effects by the next morning, you're able to have a normal day.
CoolaidWade
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AG
Don't see how this is a good idea. The effects are very short lasting. You would have to constantly be taking this to have any real relief.
GeorgiAg
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AG
I think it's more about an intense mental experience giving perspective and insight.

Check out the Ron White video

Aggie Therapist
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AG
That would be great if effective!

Went I was at the mental health hospital, I was in the high acuity wing and 50% of my caseload was suicidal patients who came in on Emergency Detention from the ER/Police.

7-10 days was the standard stay for those who came in with SI. I would imagine we would have to be ready to administer the ketamine as well if they start it at the ER. Kind of like when people come in for chemical dependence and we have to start a taper.
rjhtamu
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AG
CoolaidWade said:

Don't see how this is a good idea. The effects are very short lasting. You would have to constantly be taking this to have any real relief.
There isn't great data yet, but multiple studies are in progress. Early anecdotes is that it is potentially long lasting. Long being weeks to months potentially.
No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. See full Medical Disclaimer.
Max Power
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AG
I just wanted to provide an update on how I'm feeling since I'm done with treatment and I'll try to periodically to track how long the treatment lasts.

I'm feeling really good currently, like a weight has been lifted and I'm kinda happy as well. My anxiety generally manifests as a feeling of carrying a weight on my chest and it's just not there right now. It's weird, but good weird. I'm still taking my other medications for depression and anxiety but I fell better than when I started the ketamine cycle. I don't have any cravings to take ketamine either, there continues to be no addictive side effects. I feel better now than when I did when I was taking it as well so there appears to be both short term benefits and ones that take a while to set in. I'm sleeping better as well, but I don't know whether that's from the ketamine experience or a cortisone shot I had in my shoulder, or a little of both.
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