DVM Cara Campbell with the West Side Veterinary Hospital has been terrific for us. It's located on Broadway and Harkey, not far from Strickland Chevrolet. They also have a clinic nearer to 288.
The SPCA fixed our sheltie, and they have a fine reputation; no worries. My wife researched that route/option very thoroughly before going with them.
We've heard good things about Claws and Paws between Friendswood and Pearland if you are closer to them.
My wife owns Comfy Critters of Pearland, a pet-sitting service, should you need someone in the future.