Cypermethrin is moderately toxic through skin contact or ingestion. It may cause irritation to the skin and eyes. Symptoms of dermal exposure include numbness, tingling, itching, burning sensation, loss of bladder control, incoordination, seizures and possible death. Pyrethroids may adversely affect the central nervous system. Human volunteers given dermal doses of 130 ug/cm2 on the earlobe experienced local tingling and burning sensations. One man died after eating a meal cooked in a 10% cypermethrin concentrate that was mistakenly used for cooking oil.[url=https://en.wikipedia.org/wiki/Cypermethrin#cite_note-4][4][/url] Shortly after the meal, the victim experienced nausea, prolonged vomiting, stomach pains, and diarrhea which progressed to convulsions, unconsciousness and coma. Other family members exhibited milder symptoms and survived after hospital treatment. Cypermethrin is not a skin or eye irritant, but it may cause allergic skin reactions.[url=https://en.wikipedia.org/wiki/Cypermethrin#cite_note-5][5][/url] Excessive exposure can cause nausea, headache, muscle weakness, salivation, shortness of breath and seizures. In humans, cypermethrin is deactivated by enzymatic hydrolysis to several carboxylic acid metabolites, which are eliminated in the urine. Worker exposure to the chemical can be monitored by measurement of the urinary metabolites, while severe overdosage may be confirmed by quantitation of cypermethrin in blood or plasma.[url=https://en.wikipedia.org/wiki/Cypermethrin#cite_note-6][6][/url]
