quote:
AN OVERDOSE CAN KILL YOUR DOG
YMMV, but people recommend 1/10cc of 1% pig or bovine solution per 10lbs of dog.
A vet at the big school told me they dilute the Ivomec with propylene glycol (10:1), to make measurement and administration easier and more accurate.
We use the 1.87% equine paste..I'll not share the calculated/correct quantity, but I used my reloading scale to measure it. It has worked for me for over 20yrs....YMMV. All of our dogs are 50+ lbs in weight, making dosing easier.
As for the precision of the dose: the Heartgard application range is 2x (weight range), plus the directions state "if you're not sure the dog consumed all of the dose, give them another". And regarding safety---
This from PetMD:
- 6 ug/kg for heartworm prevention
- 300 ug/kg for treatment of sarcoptic mange
- 400-600 ug/kg for treatment of demodectic mange
Non-sensitive breeds generally need to be exposed to more than 2,000 ug/kg before significant symptoms develop, but the potentially toxic dose in MDR1 positive individuals can be as low as 100 ug/kg. Take note that the incredibly low dose used for heartworm prevention is well below the toxic dose even for even the most sensitive dogs. Before using higher doses of ivermectin, however, at risk dogs can be tested for the MDR1 gene mutation. This is especially important for breeds like Collies, Shetland Sheepdogs (Shelties), Australian Shepherds, Old English Sheepdogs, English Shepherds, German Shepherds, Long-haired Whippets, Silken Windhounds, and mutts that might be derived from these breeds.