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In a written answer to a question posed by The Associated Press, the department said that all U.S. visa holders are subject to "continuous vetting" with an eye toward any indication that they could be ineligible for the document.
Should such information be found, the visa will be revoked and, if the visa holder is in the United States, he or she would be subject to deportation.
The department said it was looking for indicators of ineligibility, including visa overstays, criminal activity, threats to public safety, engaging in any form of terrorist activity, or providing support to a terrorist organization.
"We review all available information as part of our vetting, including law enforcement or immigration records or any other information that comes to light after visa issuance indicating a potential ineligibility," the department said.
Since President Donald Trump took office in January, his administration has thus far focused on deporting migrants illegally in the United States as well as holders of student and visitor exchange visas. The State Department's new language suggests that the re-vetting process, which officials acknowledge is time-consuming, is far more widespread.