I know quite a bit about this topic,
1) Addiction, certain types of depression, and PTSD rewire your brain so that it is difficult to make decisions that normal people can make.
2) The brain rewiring is not only psychological, it is physical in nature. Certain neural pathways decay, other new neural pathways are formed, and other neural pathways are strengthened. The result is that the wiring in your brain is physically changed in a way that is detrimental to some types of routine decision making. The physical re-wiring makes overcoming the problems with these diseases very difficult, as you have to physically re-wire again.
3) Psychedelics bathe your brain in serotonin, resulting in: 1) ChatGPT-1 level hallucinations (with more colors), and 2) a brain chemistry that encourages rapid and significant brain re-wiring. It is this re-re-wiring of the brain that has provided relief to people that suffer from hard to treat depression, addiction, and PTSD. The ability of your brain to re-wire in this way is called neuroplasticity. When I was in high-school this was thought to be impossible for adults. We have learned a ton about this subject over the last 3 decades.
4) Tons of clinical research on this, with clinical trials showing recovery from diseases that normally show recovery rates in the teens to have recovery rates between 80 percent and 90 percent, just unheard of, Godly good results. The most impactful study was by Johns Hopkins. It has been replicated by organizations such as Stanford, Mayo Clinic, etc. Respected research organizations.
5) The protocol for treatment is a combination of talk therapy / intentionality to use the treatment to fight the disease / psychedelic medicines. The talk therapy and prep seem to be very important to the positive results.
6) These are meant to be more of a cure than a treatment. The re-re-wiring hopefully happens in one to three big hero-level trips. The clinical trials for micro-dosing are still pretty young. It's less like insulin and more like chemo, but for diseases related to troublesome brain wiring.
7) Psychedelics are abused as party drugs, but they are not physically addictive, not toxic, and non-habit forming in the way that alcohol / opioids / nicotine / caffeine is. Just the opposite, they help people break bad habits and patterns of thinking.
8) Psychedelics can lead to people making really bad decisions while they are tripping. Taking them in a clinical setting where the patient is being monitored is designed to eliminate the risk of injury or harm during the treatment.
9) I think it more likely than not that we see this class of drugs become more mainstream within the next decade, with FDA approval of some of these drugs for medical treatments related to these psychoses.
Additional information:
https://www.hubermanlab.com/episode/how-psilocybin-can-rewire-our-brain-its-therapeutic-benefits-and-its-riskshttps://www.hopkinsmedicine.org/psychiatry/research/psychedelics-researchhttps://www.nature.com/articles/s44184-024-00068-9Feel free to DM me if you have any questions.
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