Nobel for Discovery of Function for "Junk DNA" | Evolution News
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What's the biggest science story of the year? My vote goes to the 2024 Nobel Prize in Physiology or Medicine, awarded for the discovery of function for a type of "junk DNA" that produces microRNA (miRNA), a crucial molecule involved in gene regulation. That so-called genetic junk would turn out to be functional was a prediction of intelligent design going back to the 1990s. On that, ID has been vindicated over and over again, now by the Nobel Committee. Our colleagues Richard Sternberg and Bill Dembski were early predictors, as critics of what Jonathan Wells called in a 2011 book, The Myth of Junk DNA.
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Now the official Nobel Prize press release does not say that microRNAs are produced by a type of DNA once considered "junk." But leading scientists make this exact point. An article in Current Science about this year's Prize states:The Science Media Centre of Spain reports that a biochemist at the Autonomous University of Madrid remarked:Quote:
Although, by the early 1990s some non-coding 'genes' including the hsr in Drosophila, Xist, H19, etc. in mammals were known to be essential for organisms' normal lives, they remained exceptions without making any dent in the widespread text-book level strong belief in 'selfish' or 'junk' DNA. In this backdrop, Ambros and Ruvkun groups' discovery that the lin-4 gene of C. elegans produces a small non-coding RNA (ncRNA) that inhibits activity of the lin-14 gene through RNA interference decisively catalysed a widespread interest in ncRNAs that hitherto had remained rather 'ostracized'. RNA interference also explained the mystery of the earlier known phenomena like post-transcriptional gene silencing and 'quelling'.Quote:
This finding is of great importance, transforming our understanding of the regulation of gene expression and attributing critical functions to a fraction of the human genome that was previously considered 'junk DNA' because it does not code for proteins.