Anyone ever played some of the Jackbox games or other similar over Twitch? Does it work well?

lgb indeed

Most jackbox games, yes. The caveat would be that most games can only play up to 8 people.

For the games that work well, even if everyone isn't in the same room (ie twitch, zoom, etc):
Jackbox 3 has quiplash 2, trivia murder party and guesspionage. Jackbox 4 has fibbage 2, bracketeering and survive the internet
Jackbox 5 has split the room
Jackbox 6 has trivia murder party 2, push the button and dictionarium

I haven't enjoyed the jackbox games.

yes, plenty of times. Among us works well on twitch too if people aren't cheaters.

Do you have more questions about it?

You have to make sure you turn the broadcast delay off. We tried it several times during covid and couldn't get it to work well with timed responses and such. So, instead, we just initiated a zoom call in which the game screen was a separate participant in the call. That worked a lot better.

or use discord as a room

Thanks for the tip.
I'm not great with technology.