It is being reported that a string immune reaction to one of the harmless coronaviruses is associated with stronger immune response to covid.

From https://scitechdaily.com/exposure-to-harmless-coronaviruses-boosts-covid-19-immunity/

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Infections with the novel coronavirus and vaccination lead to strong antibody responses against SARS-CoV-2. Immune responses to other human coronaviruses, which mostly only cause harmless colds, also provide some protection against SARS-CoV-2. This cross-reactive immune response is an important piece of the puzzle of how to achieve comprehensive coronavirus immunity, researchers at the University of Zurich have shown.



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The researchers were able to demonstrate that people who caught SARS-CoV-2 had lower levels of antibodies against coronaviruses that cause common colds compared to uninfected people. In addition, people with high levels of antibodies against harmless coronaviruses were less likely to have been hospitalized after catching SARS-CoV-2. "Our study shows that a strong antibody response to human coronaviruses increases the level of antibodies against SARS-CoV-2. So someone who has gained immunity to harmless coronaviruses is therefore also better protected against severe SARS-CoV-2 infections," says Trkola. This type of immune response is referred to as cross-reactivity, and it also occurs with T cell responses, the additional line of the immune system in the defense against infections.

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texan12 said:

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Unless you live in a bubble, who hasn't gotten the cold before?

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You could have had the cold many times without getting one caused by one of the non-dangerous coronaviruses. I think that the most common cold virus is a rhinovirus.

Full text of The Lancet article:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00674-5/fulltext

Kind of like getting cowpox to prevent smallpox?

I had wanted to reply to this a few days ago, but just have been too busy.

From my very unlearned and non-scientific, but very much 3rd world living, background there has to be something to certain groups having some kind of immunity or resistance. Look no further than Haiti and Nicaragua, the two poorest countries in this hemisphere and Africa as a whole continent. I lived in both Haiti and Nicaragua and can vouch that there is constant maladies making the rounds, many known and unknown.

Look at the death and cases statistics difference between Haiti and the DR, on the same island. My former Dominican coworkers and employees in Haiti opted to stay in Haiti instead of going to the DR during the height of the deal, there was that much of a perceived difference. There will be folks that say Haiti isn't counting or they don't test, etc. But they just actually never had the death runups that the DR did, nor the panic. Same in Nicaragua compared to Costa Rica. Both the Nicaraguan and Haitian populations are more unhealthy and exposed to a lot more viruses and stuff than their immediate neighbors. Why the difference? And it ain't closed borders.

The lower socio-economic class Mexicans that I work with also seemed to skate through the height of the pandemic fine. We never had any deaths, knock on wood and thank the Lord, but we did have 2 employees, one young man and another an older woman end up not being able to come back to work after being vaccinated. The young man, coincidence or not, developed some kind of heart issue and has real odd fluctuations. The older lady just got really, really sick and several weeks later tested positive for Covid. I had Covid early on, wife tested positive and then so did I, and had not one symptom other than loss of taste and smell (never really has come back).

Exposure, and maybe frequency of exposure, must have something to do with this family of viruses.