Natural immunity increasing over time?

2,423 Views | 5 Replies | Last: 3 yr ago by dreyOO
Guy on a Buffalo
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AG
I was infected with Covid on July 20th and did the 8-10 day recovery that mirrored what I consider the most common course of the virus in someone who experiences significant symptoms (myalgias, eye pain, headaches, fever, loss of smell and taste, cough, etc).

I was never jabbed, and besides Tylenol I only took ivermectin as a therapeutic throughout the course of the infection.

Afterwards I joined the Texas Cares study and had my labs done on August 12. As you might expect, I was positive for Covid antibodies and out of the normal range for someone who would otherwise not have them. For the two proteins they test for, N and S, my values were 20.8 (normal <1) and 75.2 (normal <0.8) respectively.

Fast forward 3 months and I once again had my labs drawn yesterday. Interestingly enough, my values have significantly increased in both tests, to 75.5 and 188.

I'm not sure if this is an indication that my natural immunity is continually increasing, or if maybe I had my first labs drawn too soon after infection to properly quantify how strongly my blood would respond when exposed to the proteins. Perhaps I had not "fully" recovered at the time of the first test.

Texas Cares will do another lab panel in three months, so potentially the trend will confirm or deny this theory of increasing immunity. Just thought it was an interesting data point to share.

TLDR: Dear diary, I never got jabbed but I made my own vaccine and it seems to be more effective than Pfizer's or Moderna's.

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Truth without love is brutality. Love without truth is compromise.
Dad
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AG
The Texas Cares thread shows that antibodies increase for a while after infection and if you get the antibody test soon after infection like you did you will have higher numbers 3 months later. At some point, the numbers will start to drop off unless you get a natural booster by getting exposed again.
texan12
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Does this study consider T cell memory?

https://directorsblog.nih.gov/2020/07/28/immune-t-cells-may-offer-lasting-protection-against-covid-19/

Much of the study on the immune response to SARS-CoV-2, the novel coronavirus that causes COVID-19, has focused on the production of antibodies. But, in fact, immune cells known as memory T cells also play an important role in the ability of our immune systems to protect us against many viral infections, includingit now appearsCOVID-19.

An intriguing new study of these memory T cells suggests they might protect some people newly infected with SARS-CoV-2 by remembering past encounters with other human coronaviruses. This might potentially explain why some people seem to fend off the virus and may be less susceptible to becoming severely ill with COVID-19.

KidDoc
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AG
On your initial blood draw so close to acute infection your titers were likely still trending up and not at their ceiling yet. So you have not really increased over time you just had a draw too early before they peaked.

This graph is for vaccine but wild infection has a similar timing pattern. So takes 20-30 days to peak.
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Guy on a Buffalo
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AG
KidDoc said:

On your initial blood draw so close to acute infection your titers were likely still trending up and not at their ceiling yet. So you have not really increased over time you just had a draw too early before they peaked.

This graph is for vaccine but wild infection has a similar timing pattern. So takes 20-30 days to peak.


That makes a lot of sense, thanks for sharing.

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Truth without love is brutality. Love without truth is compromise.
dreyOO
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My wife is a teacher and my kids are in primary school. We beat covid down about 15mos ago and have constantly been re-exposed to it. I'm in sales and am out and about. Basically, we just went back to living our lives. I'll make platinum this year with Marriott for instance.

All that to say we get retested all the time for Covid and have never been reinfected. 15 mos of ongoing exposure. Been to AZ, TX, Wy, NM, MO, MT, MN, AR and Mexico multiple times since then. I know ppl like to blame us as being super spreaders, but the facts remain that we have been exposed to MANY covid positive ppl, and it never sticks with us again. Countless examples.

None of that matters I suppose because lord Fauci doesn't bless it.

ETA: my simpleton theory is that regular exposure with natural immunity is a good thing. Going outside in the sun, living a fun healthy life is a good thing. Worrying for illness is the opposite of what we should be doing with something like Covid.
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