Father in law went into ER last night for covid pneumonia. Wife went to see him today in ICU. It was her aunt that took him in and she found out they put him on Remdesivir amd she is freaking out. She's snuck in ivermectin to him to keep taking orally.

Wife got there today to take over as lead contact. Her aunt told her she has to fight as hard as she can to get him off Remdesivir and onto HCQ because he's diabetic and she's convinced he will have renal failure from it because of 3 doctors she will only listen to that go on Alex Jones.

Everything I can find seems to say there is no extra risk, or significant enough to be worth taking him off while he's fighting to get O2.

Anyone know if there is legitimate danger worth advocating taking him off?

Infection_Ag11 said:

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It's not so much that remdesivir causes kidney issues (I mean technically it can, as almost any drug can) but that it can be an issue if you already have underlying kidney issues. There are certain (largely theoretical) concerns about the accumulation of various metabolites that could cause problems elsewhere in those which existing severe renal impairment.

That being said, at the stage when most patients present to the hospital with hypoxia steroids do most of the heavy lifting.

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So, with the wife's step mom and aunt raising hell about getting him off of Remdesivir is it worth fighting with them to keep him on it? He is on a bipap and the doc said he needs to be on remdesivir for 3 more days.

Infection_Ag11 said:

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Texaggie7nine said:

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Infection_Ag11 said:

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It's not so much that remdesivir causes kidney issues (I mean technically it can, as almost any drug can) but that it can be an issue if you already have underlying kidney issues. There are certain (largely theoretical) concerns about the accumulation of various metabolites that could cause problems elsewhere in those which existing severe renal impairment.

That being said, at the stage when most patients present to the hospital with hypoxia steroids do most of the heavy lifting.

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So, with the wife's step mom and aunt raising hell about getting him off of Remdesivir is it worth fighting with them to keep him on it? He is on a bipap and the doc said he needs to be on remdesivir for 3 more days.

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I'd say the potential benefit outweighs the potential harm. But he really needs to be on high dose steroids, and probably needs to be considered for toci if it's available at the facility he's being treated at.

Maybe most importantly, if he's not retaining CO2 as well, he's likely better off on high flow nasal cannula than bipap. Covid patients do better the less positive airway pressure you apply generally speaking. It's one reason they do so poorly once they are intubated.

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Is that something we can advocate for to thr ICU doc?

Also, thr nurse said that off O2 they can't keep O2 over 79. On nasal cannula it gets around 90 and on bipap its up at 99. I think because he breaths mostly through his mouth.

Ok thank you

They took him off bipap wed. He seemed to be doing better on canula, but yesterday took a downturn and he's back on the bipap struggling to stay in high 80s. Finished remdisivere.

Prayers for a full recovery.

He's now been taken to ICU onto a vent and sedated. Thankfully wife got to go see him before they took him.

96AustinAg said:

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"sneaking in medicine" to the hospital is quite literally one of the dumbest ideas I've ever heard. Major hospital docs have a S-H-I-T---T-O-N of experience treating Covid and keeping people from dying. Let them drive the patient care. If you have a concern with something, bring it up to them.

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His aunt did it. He's asking for advice and seems to be taking it from docs. His dad was also just put on a ventilator. How about you follow along.