ELOX

5,476 Views | 24 Replies | Last: 2 yr ago by La Bamba
La Bamba
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Figured OA mass accumulation names probably deserve their own thread as a way of consolidating information and updates about the aforementioned. I am going to drop a few key pieces of information below, state sources, and hopefully folks will build on it and the board can find it useful. If not, we can keep posting updates on the main thread if this is redundant.

The beginning excerpt below is actually from reddit (here's the full link https://www.reddit.com/r/pennystocks/comments/ok8idv/eloxx_pharmaceuticals_nasdaqelox_dd/). Before you dismiss it, below the excerpt are the Form 4/13D/13G filings from the company's website that validate the reddit post. To me, unless I read it in a filing or confirm it in a filing, it's not real.


Quote:

Insider/Institutional Buying:
The money pipeline drug, ELX-02, is currently in Stage 2, and the results were scheduled to be released in H1 2021. But, due to COVID-19, allegedly, management announced that the results would be heading towards H2 2021. If this reading goes well, the valuation will increase exponentially. So, obviously, most of the public is waiting on the results of this reading in order to decide whether to invest. However, what gets really interesting is that there has been quite a bit of signaling as to these results might be positive.
1. After announcing the delay of the Stage 2 reading, on May 18th, Eloxx completed a secondary private offering to avoid the public markets. On the surface, this may seem like a non-material point. However, is it likely that insiders would want the shares to get out to the public if they knew they had potentially strong phase 2 results incoming? The answer is unlikely. During this offering, institutions purchased 30% of the company. If you trace back who were the major purchasers of the aforementioned offering were, you find that it was Pontifax. Pontifax is an Israeli biopharma venture capital fund who have a strong history of great performance and exits. Additionally, Pontifax isn't just casting a wide spread with a lot of investments Pontifax put $0 into other public holdings in the past year; Elox was the exception not just a drop in the bucket.
However, if you dive further into this Pontifax purchase, Pontifax's CEO, Tomer Kariv, used to be the CEO and Founder of Eloxx. Kariv also currently still serves as the chairman of the board at Elox itself. So, Kariv, the former founder of Elox, who arguably knows more than anyone about the company, just purchased a large ownership in the company prior to the biggest reading in the company's history.
So, putting the above in simple terms, Elox delayed their Stage 2 reading. Elox insiders, who realistically have some idea how the Stage 2 is going, prevented Elox from going to the public markets and instead purchased 30% of the company for themselves.
2) Enter Roche Finance. Roche Finance is a unit of the Swiss pharma giant Roche Holdings ($330bn market cap). On June 14th, Roche Finance disclosed that they have purchased an ownership stake of 5.3% of Eloxx Pharmaceutical. If you want to look up Roche further, they have incredibly strong performance and a history of investing in winners.
So take another step back, following that 30% purchase from insiders, another major pharma player purchased an additional 5.3% of Elox.
3) Now, if that wasn't enough institutional and insider buying, I still have more for you. Enter Ernesto Bertarelli and Waypoint Holdings/Gurnet Point. I am sure hardly anybody has heard of Bertarelli, but Bertarelli is a billionaire with a strong biopharma background. Bertarelli was the CEO of Serono, which was a major producer of MS drug Rebif. The details of his specific background is not incredibly important. However, Bertarelli and his funds Waypoint/Gurnet purchased 5.7% of Eloxx Pharma announced on June 29th.



Here's the Pontifax May 17th Form 4 straight from the ELOX website (you can find this on sec.gov/edgar as well…). Seems like most of these guys purchased at $1.35.
https://investors.eloxxpharma.com/static-files/8499716f-859f-4b7b-9182-6d9b7897ff64
https://investors.eloxxpharma.com/static-files/97537033-f0bc-469f-b1f3-b1dfe9157df1 (Tomer Kariv, Pontifax CEO)
https://investors.eloxxpharma.com/static-files/81720933-58cc-4542-b17a-9c4ee6571e74 (Ran Nussbaum, Pontifax managing partner and co-founder)

Here's another list of filings from May 17th and May 20th of ELOX company officials and BoDs increasing their stake in the company:
https://investors.eloxxpharma.com/static-files/1774d4f6-e576-4944-84a3-d5726cc6db43 (Sumit Aggarwal, ELOX CEO)
https://investors.eloxxpharma.com/static-files/34fbff24-37ee-4041-b4a7-a713b6cf4638 (Parekh Rajesh, ELOX Board of Directors)
https://investors.eloxxpharma.com/static-files/9874c445-7dfe-4951-b39e-1fa2698d5f38 (Vijay Modur, ELOX head of R&D)
https://investors.eloxxpharma.com/static-files/1ddb84c7-8fbc-42f8-96ae-93ba8d5f466d (Avnur Zafrira, ELOX Board of Directors)

On May 20th, pretty much all the members of the board filed an increase in ownership with the SEC. You can find all of these on the ELOX website (won't post them all here, you get the point).

Then the Roche Finance 13G:
https://investors.eloxxpharma.com/static-files/6912f5e4-9afe-41ad-8433-99945cfeb7d1

Then the Waypoint 13G
https://investors.eloxxpharma.com/static-files/4e0cf553-eaea-4954-893d-4dc567dc4404

As a further note, here are the following Institutional/Insider Ownership numbers from a few different sources:
Finviz: Insider Own is 9.37% and Inst Own is 34.40% …..so 43.77% of the float is owned by the big money
Yahoo Finance: Insider Own is 9.37% and Inst Own is 34.35% …..so 43.72% of the float is owned by the big money. Same numbers.

I like to short stocks while day trading (rarely go long unless swing/long term buys), especially small cap stocks that run on big news and have big dilution events on their hands. As a general rule, I stay away from names that have >40% insider buying because the remaining float just isn't big enough for retail to panic sell after buying the top and have a big enough move downwards. A smaller "retail" float also increases risk of getting taken for a ride upwards while short. Looking at it from that perspective, this is obviously bullish for me on this particular name.

Drug Candidate Validation
ELX-02 has received Orphan Drug Designation on April 30, 2018 and was recently granted Fast Track Designation from FDA on September 9, 2021. The latter has also coincided with big volume on the chart and a nice positive uptrend ever since.


The company has also received funding from the Cystic Fibrosis Foundation to the tune of 2.5 million dollars for novel treatments of CF. Recognition from the CF Foundation is indicative that this company is for real and validates its efforts in my eyes.

Quote:

Mr. Aggarwal continued, "In addition, the development of a Ribosome Modulating Agent for the treatment of CF with support from the Cystic Fibrosis Foundation complements our ongoing ELX-02 program, currently in Phase 2 clinical trials. Data from these Phase 2 trials is expected in the second half of this year."

Risks and Dilution
At the end of the day, the value here rests with the ELX-02 drug and positive phase 2 results. In addition, the company has a $200 million shelf from August 2021 where they can dilute more shares to raise money, as obviously they do not have a drug that currently produces them revenue to keep the lights on.
https://investors.eloxxpharma.com/static-files/2d116b1b-1f98-4ae1-adb4-6b33fcb64ca8

Summary
If the company can deliver on ELX-02, there is massive value to be gained here, as the drug is targeting a population of patients with no current treatment (different addressable market than Vertex). But to me, the insider buying at $1.35 and the chart supporting in and around that level, plus the validation from the FDA and CF Foundation, makes me like the risk/reward proposition.
Bird Poo
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Great post! Thank you.
PDEMDHC
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I just saw you did this. Thanks for the great information!
tam2002
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Do we think October will be a good month for elox? Should be some kind of run into results right?
BlueTaze
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I think the large vol of covered calls has to clear before this really runs. Lots of Oct and Nov $2.50 call premium to expire before this takes off IMO.

Hope I'm wrong!
La Bamba
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BlueTaze said:

I think the large vol of covered calls has to clear before this really runs. Lots of Oct and Nov $2.50 call premium to expire before this takes off IMO.

Hope I'm wrong!

Is that what you think happens or what you hope happens? I bet you have a few of those CC getting filled and hope aren't getting executed so you keep your shares.

I think OA (and I can look for the tweet) was thinking we could see $3.50 before the Phase 2 clinical results were revealed at end of the year. Sort of hard to see that happening right now with the macro market weakness but we shall see. S&P is already down 5% from highs and ELOX is at least holding up along that trend line.
La Bamba
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September 30, 2021 Update: ELOX files Form 424B5 announcing an "at-the-market" offering of upto $50 million dollars in new shares to be sold. Current outstanding shares at 86 million - assuming a sales price of $1.75 that could mean an additional 29 million shares in dilution to fund expenses, R&D, etc. This is a takedown of the $200 milly S-3 that they filed in August, so we knew at some point they were going to execute on that shelf.

They will probably wait until Phase 2 results are released, and we get a jump in share price and liquidity, to sell the new shares. Diluting at current prices with a few 100k in volume will completely decimate the share price. If they sell at higher prices will mean less dilution to get to the 50 mil. So once we get that spike, there is your chance to sell, do not hold thinking for a continuation move (just my opinion, maybe I'm wrong).

Obviously the name of the game with these hyper speculative names - get good news - they dilute - generate cash to keep business alive until they have a sellable product. Just is what it is.

https://investors.eloxxpharma.com/static-files/51f51d93-efc5-4d1f-806d-dc000f1f0c7a
PDEMDHC
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Great work.

From the positive trend line discussion, looks like it needs to close above $1.59 for this to hold the trend line...
PDEMDHC
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What happened after hours? That's a nearly 10% move down AH and no news/trading.
H-town ag
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Carlo4 said:

What happened after hours? That's a nearly 10% move down AH and no news/trading.
They announced an investor call next Tuesday ...

https://investors.eloxxpharma.com/news-releases/news-release-details/eloxx-pharmaceuticals-host-investor-and-analyst-call-and-webcast


"Eloxx Pharmaceuticals, Inc. (Nasdaq: ELOX), today announced that it will host anInvestor and Analyst call and webcast on Tuesday, October 12, 2021. The event will include an update on the company's cystic fibrosis programs and will feature Dr. Eitan Kerem, a globally renowned CF expert. The event is intended to provide insight into Eloxx' CF programs, as data from the ongoing Phase 2 trials in CF are expected in the fourth quarter of 2021."



Maybe there is disappointment that the data / report from the trials is not coming sooner.
tam2002
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I thought it was expected to come out in the 4th qrt?
La Bamba
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tam2002 said:

I thought it was expected to come out in the 4th qrt?
Well October is technically in the 4th qtr.

More info on Dr. Kerem below. Looks like he's been involved with ELOX for a while. This dude is major in the CF world.

https://www.globenewswire.com/news-release/2020/09/14/2093083/0/en/Globally-Renowned-Cystic-Fibrosis-Expert-Dr-Eitan-Kerem-Joins-Eloxx-Pharmaceuticals-as-a-Senior-Consultant.html

https://www.hadassahmagazine.org/2016/09/27/past-present-future-cystic-fibrosis/

https://www.cipp-meeting.org/en/faculty-members/id-7-eitan-kerem
tam2002
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La Bamba said:

tam2002 said:

I thought it was expected to come out in the 4th qrt?
Well October is technically in the 4th qtr.

More info on Dr. Kerem below. Looks like he's been involved with ELOX for a while. This dude is major in the CF world.

https://www.globenewswire.com/news-release/2020/09/14/2093083/0/en/Globally-Renowned-Cystic-Fibrosis-Expert-Dr-Eitan-Kerem-Joins-Eloxx-Pharmaceuticals-as-a-Senior-Consultant.html

https://www.hadassahmagazine.org/2016/09/27/past-present-future-cystic-fibrosis/

https://www.cipp-meeting.org/en/faculty-members/id-7-eitan-kerem


Well I'm at a loss to know what to think about this
La Bamba
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Bit of a non-event if you ask me. Participation from Dr. Kerem was solely to demonstrate demand for lack of therapies in Class 1 cases and show the global market for therapies in this space (I think they had 5billion potential). Perhaps having him join to go over this was more of a credibility thing to what ELOXX is doing rather than anything else cause I'm not sure it was new information.

Seemed very tight lipped on the Phase two results and kept alluding to disclosing the data later in the 4th quarter. Would not disclose any details as to number of patients in the trials or results with high doses versus low doses.

They did key in on their excitement with the combination therapy with Kalydeco and then eventually going from an IV delivery to inhaled delivery which is obviously a very common delivery type for other CF therapies.

Low volume today on the stock despite the conference and down 2%. Wish the presentation would have had more meat on the bones.

Link to presentation
Bird Poo
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Anyone buying at these levels?
PDEMDHC
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I bailed out back at $1.55/broke even. Debating on getting back in but it won't be my serious money.
willowratio
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Made a little earlier this year, but thinking the same.
KT 90
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PearlJammin said:

Anyone buying at these levels?

OA bought more today:



tam2002
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I averaged down pretty good. I'm holding a bag but I'm confident it'll work it's way back up. It really wasn't bad news today
JbKing45
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tam2002 said:

I averaged down pretty good. I'm holding a bag but I'm confident it'll work it's way back up. It really wasn't bad news today
when is the next major news release date? Phase 3 results in late 2022?
aggies4life
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Who else is still in this??? Nice movement
Diggity
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aggies4life said:

Who else is still in this??? Nice movement


Still in...and down 85%. Have a ways to go.
scoodogg
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WOOOOOOOOOOO

Now, I'm only down 80%.
taba82
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scoodogg said:

WOOOOOOOOOOO

Now, I'm only down 80%.
+1
Mike
Aggie Band '82
La Bamba
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I took my losses last year. Rough.
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