I've always had a problem with motion sickness and i've found that two Dramamine about an hour before the activity but right after eating is the best. I've also found that drinking beer while either boating or flying always helps. It allows you to burp and alcohol is a natural remedy for motion sickness believe it or not.
I do the same thing CS78 does and have never had any problems. I get motion sickness very easily too.
Dramimine when I go to bed, another once I get a bite to eat, but at least 30 minutes before getting on the boat.
We went on a cruise once and the first night the seas were really rough. People were losing their cookies left and right. I was just fine with the dramamine.
I've also had good luck with Bonine, but store brand dramamine is cheaper and works just fine for me.
The scope patch is wonderful, but you'll need a prescription for it.
I commercial fish in Alaska for months at a time and I'm always nervous about using dramamine, because I don't like the idea of something numbing my balance basically. Falling overboard up there is pretty much the end. Anyway I know this sounds like dark magic but I take a glob of vics vapor rub and put it in my belly button and slap a band-aid over it to keep it in. It keeps me feeling great, especially when I can't see the horizon for either constant working and looking down at fish, or being too deep in a trough.
I don't usually get motion sickness anyway. In fact, I never have... but then I usually have a beer in my hand when I'm on a boat. The data doesn't lie!
some people never outgrow it or get used to it. I remember an episode of the deadliest catch where one of the crew members was seasick. He'd been crab fishing for 10-15 years and he got sick at the begining of each crab season. Once for king and once for opies every year. He said he was fine after the first time as long as he didn't get back on land for a couple days. I don't know if I could do that knowing I'd get violently ill everytime.
Go to walgreens' pharmacy counter and ask for their 100 pack of meclazine. It's the same thing as non-drowsy dramamine except you get 100 for $5 instead of 7 for $10.
Start taking them 1-2 days before you hit the boat and every few hours once you get on the boat.
I crossed the atlantic ocean this past January. I took Dramamine once a day 3 days before I left, then one a day for the first 3 days. Didn't need one the rest of the trip.
Only time I got sick was in the Meditteranean, 27 feet swells get to you eventually no matter what.