I didn't really answer your time question in regard to a commute. Depending on where you live in Helotes, you can probably make it to 151/Potranco in approximately 30 minutes. One other thing about Helotes. If you do move to the area, be absolutely sure you get a thorough inspection of the roof of the house you might buy. We had a horrendous hail storm in April of 2016 that affected thousands of houses. We had confirmed baseball-sized hail at our house, and had to get a whole new roof. Be careful what you buy, as more than one of my friends bought houses recently that ended up having workmanship issues with roofs put on in 2016/2017.
The next major intersection closer to your work is 1604 and Shaenfield. Mostly apartments and more affordable housing, and equidistant between the larger shopping areas at 1604/Bandera and 1604/Culebra.
Our son was in The Mustard Seed, a great daycare, several years ago. I'd highly recommend it if the owner is still the same. She's a former school administrator from Northside ISD.
The area has really exploded with new homes in the last decade, and once you get to know the backroads, you can mostly avoid 1604 depending on where you're wanting to go.
The next area down is Alamo Ranch (1604 and Culebra). I've spent enough time in the shopping center there (thank you, Freebirds), that I can tell you that to this day the area still needs better road infrastructure. You'll spend a lot of time in traffic on the weekends. The Alamo Ranch neighborhood farther back behind the shopping center is very nice, and just far enough away from 1604 that the neighborhood subdivisions are reportedly quiet (hoping someone that lives there can chime in). We were this close to purchasing a home there a few years ago. There's a newer movie theater (Casa Blanca), and newer H-E-B, along with a super Target and Lowe's. You can venture just inside 1604 for another H-E-B, a Home Depot, and more fast food.
As far as renting or owning, that's up to you. We rented for a year before buying. I wasn't really familiar with San Antonio when I moved here. I can tell you that there are enough neighborhoods around here that you'll probably end up finding that you want to move from wherever you initially settle.