I have. I was having trouble with continued inflammation 6 months or so after a relatively minor rotator cuff repair.
The shot hurts. I walked out holding my arm like in the movie The Right Stuff.
Did it help? Maybe. It did get better, but it wasn't for another 3 months or so, during which time quit I PT'ing/exercising. Dr Carl Palumbo did my injection. This was in 2011.
I had my other shoulder scoped twice last year, with second being a major repair. Still hurts. Contemplating a stem cell injection.
My only advice: If you haven't taken 2 or 3 months off to see if the pain decreases significantly, try it.