Depends on what your wife does and where y'all are willing to live while you get your degree.
There are some older, cheap quad plexes ($650/month for 2/2) behind the Hilton on spring loop. The area has a majority grad student population so it's pretty 'quiet' for how cheap it is.
Work wise, your wife will need to be able to work for the university, the service industry, or perfectly fit a technical opening.
There are a lot of wives in that area looking for work with roughly the same skill set. It can be hard to find a good job.